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Items: 1 to 20 of 47


Lessons from (pre-)mRNA Imaging.

Adivarahan S, Zenklusen D.

Adv Exp Med Biol. 2019;1203:247-284. doi: 10.1007/978-3-030-31434-7_9. Review.


Live-Cell Imaging of mRNP-NPC Interactions in Budding Yeast.

Lari A, Farzam F, Bensidoun P, Oeffinger M, Zenklusen D, Grunwald D, Montpetit B.

Methods Mol Biol. 2019;2038:131-150. doi: 10.1007/978-1-4939-9674-2_9.


Spatial Organization of Single mRNPs at Different Stages of the Gene Expression Pathway.

Adivarahan S, Livingston N, Nicholson B, Rahman S, Wu B, Rissland OS, Zenklusen D.

Mol Cell. 2018 Nov 15;72(4):727-738.e5. doi: 10.1016/j.molcel.2018.10.010. Epub 2018 Nov 8.


Senescence-associated ribosome biogenesis defects contributes to cell cycle arrest through the Rb pathway.

Lessard F, Igelmann S, Trahan C, Huot G, Saint-Germain E, Mignacca L, Del Toro N, Lopes-Paciencia S, Le CalvĂ© B, Montero M, DeschĂȘnes-Simard X, Bury M, Moiseeva O, Rowell MC, Zorca CE, Zenklusen D, Brakier-Gingras L, Bourdeau V, Oeffinger M, Ferbeyre G.

Nat Cell Biol. 2018 Jul;20(7):789-799. doi: 10.1038/s41556-018-0127-y. Epub 2018 Jun 25.


Visualization of Arenavirus RNA Species in Individual Cells by Single-Molecule Fluorescence In Situ Hybridization Suggests a Model of Cyclical Infection and Clearance during Persistence.

King BR, Samacoits A, Eisenhauer PL, Ziegler CM, Bruce EA, Zenklusen D, Zimmer C, Mueller F, Botten J.

J Virol. 2018 May 29;92(12). pii: e02241-17. doi: 10.1128/JVI.02241-17. Print 2018 Jun 15.


Measuring mRNA Decay in Budding Yeast Using Single Molecule FISH.

Trcek T, Rahman S, Zenklusen D.

Methods Mol Biol. 2018;1720:35-54. doi: 10.1007/978-1-4939-7540-2_4.


Nol12 is a multifunctional RNA binding protein at the nexus of RNA and DNA metabolism.

Scott DD, Trahan C, Zindy PJ, Aguilar LC, Delubac MY, Van Nostrand EL, Adivarahan S, Wei KE, Yeo GW, Zenklusen D, Oeffinger M.

Nucleic Acids Res. 2017 Dec 1;45(21):12509-12528. doi: 10.1093/nar/gkx963.


Visualization of the lymphocytic choriomeningitis mammarenavirus (LCMV) genome reveals the early endosome as a possible site for genome replication and viral particle  pre-assembly.

King BR, Kellner S, Eisenhauer PL, Bruce EA, Ziegler CM, Zenklusen D, Botten JW.

J Gen Virol. 2017 Oct;98(10):2454-2460. doi: 10.1099/jgv.0.000930.


Single-cell profiling reveals that eRNA accumulation at enhancer-promoter loops is not required to sustain transcription.

Rahman S, Zorca CE, Traboulsi T, Noutahi E, Krause MR, Mader S, Zenklusen D.

Nucleic Acids Res. 2017 Apr 7;45(6):3017-3030. doi: 10.1093/nar/gkw1220.


Structure and Function of the Nuclear Pore Complex Cytoplasmic mRNA Export Platform.

Fernandez-Martinez J, Kim SJ, Shi Y, Upla P, Pellarin R, Gagnon M, Chemmama IE, Wang J, Nudelman I, Zhang W, Williams R, Rice WJ, Stokes DL, Zenklusen D, Chait BT, Sali A, Rout MP.

Cell. 2016 Nov 17;167(5):1215-1228.e25. doi: 10.1016/j.cell.2016.10.028. Epub 2016 Nov 10.


Imaging single mRNAs to study dynamics of mRNA export in the yeast Saccharomyces cerevisiae.

Bensidoun P, Raymond P, Oeffinger M, Zenklusen D.

Methods. 2016 Apr 1;98:104-114. doi: 10.1016/j.ymeth.2016.01.006. Epub 2016 Jan 16.


The nuclear basket mediates perinuclear mRNA scanning in budding yeast.

Saroufim MA, Bensidoun P, Raymond P, Rahman S, Krause MR, Oeffinger M, Zenklusen D.

J Cell Biol. 2015 Dec 21;211(6):1131-40. doi: 10.1083/jcb.201503070.


In vivo single-particle imaging of nuclear mRNA export in budding yeast demonstrates an essential role for Mex67p.

Smith C, Lari A, Derrer CP, Ouwehand A, Rossouw A, Huisman M, Dange T, Hopman M, Joseph A, Zenklusen D, Weis K, Grunwald D, Montpetit B.

J Cell Biol. 2015 Dec 21;211(6):1121-30. doi: 10.1083/jcb.201503135.


Promoter-Autonomous Functioning in a Controlled Environment using Single Molecule FISH.

Hocine S, Vera M, Zenklusen D, Singer RH.

Sci Rep. 2015 May 28;5:9934. doi: 10.1038/srep09934.


Myosin VI regulates gene pairing and transcriptional pause release in T cells.

Zorca CE, Kim LK, Kim YJ, Krause MR, Zenklusen D, Spilianakis CG, Flavell RA.

Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):E1587-93. doi: 10.1073/pnas.1502461112. Epub 2015 Mar 13.


Single-molecule resolution fluorescent in situ hybridization (smFISH) in the yeast S. cerevisiae.

Rahman S, Zenklusen D.

Methods Mol Biol. 2013;1042:33-46. doi: 10.1007/978-1-62703-526-2_3.


Bimodal expression of PHO84 is modulated by early termination of antisense transcription.

Castelnuovo M, Rahman S, Guffanti E, Infantino V, Stutz F, Zenklusen D.

Nat Struct Mol Biol. 2013 Jul;20(7):851-8. doi: 10.1038/nsmb.2598. Epub 2013 Jun 16.


A nutrient-responsive pathway that determines M phase timing through control of B-cyclin mRNA stability.

Messier V, Zenklusen D, Michnick SW.

Cell. 2013 May 23;153(5):1080-93. doi: 10.1016/j.cell.2013.04.035.


Single-molecule analysis of gene expression using two-color RNA labeling in live yeast.

Hocine S, Raymond P, Zenklusen D, Chao JA, Singer RH.

Nat Methods. 2013 Feb;10(2):119-21. doi: 10.1038/nmeth.2305. Epub 2012 Dec 23.


To the pore and through the pore: a story of mRNA export kinetics.

Oeffinger M, Zenklusen D.

Biochim Biophys Acta. 2012 Jun;1819(6):494-506. doi: 10.1016/j.bbagrm.2012.02.011. Epub 2012 Feb 22. Review.

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