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Items: 1 to 20 of 155


Context-explorer: Analysis of spatially organized protein expression in high-throughput screens.

Ostblom J, Nazareth EJP, Tewary M, Zandstra PW.

PLoS Comput Biol. 2019 Jan 2;15(1):e1006384. doi: 10.1371/journal.pcbi.1006384. eCollection 2019 Jan.


Patterned Optoelectronic Tweezers: A New Scheme for Selecting, Moving, and Storing Dielectric Particles and Cells.

Zhang S, Shakiba N, Chen Y, Zhang Y, Tian P, Singh J, Chamberlain MD, Satkauskas M, Flood AG, Kherani NP, Yu S, Zandstra PW, Wheeler AR.

Small. 2018 Nov;14(45):e1803342. doi: 10.1002/smll.201803342. Epub 2018 Oct 11.


Stem cell bioengineering: building from stem cell biology.

Tewary M, Shakiba N, Zandstra PW.

Nat Rev Genet. 2018 Oct;19(10):595-614. doi: 10.1038/s41576-018-0040-z. Review.


Mechanics-guided developmental fate patterning.

Tewary M, Zandstra PW.

Nat Mater. 2018 Jul;17(7):571-572. doi: 10.1038/s41563-018-0121-6. No abstract available.


Modulating cell state to enhance suspension expansion of human pluripotent stem cells.

Lipsitz YY, Woodford C, Yin T, Hanna JH, Zandstra PW.

Proc Natl Acad Sci U S A. 2018 Jun 19;115(25):6369-6374. doi: 10.1073/pnas.1714099115. Epub 2018 Jun 4.


Author Correction: A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies.

Bahr C, von Paleske L, Uslu VV, Remeseiro S, Takayama N, Ng SW, Murison A, Langenfeld K, Petretich M, Scognamiglio R, Zeisberger P, Benk AS, Amit I, Zandstra PW, Lupien M, Dick JE, Trumpp A, Spitz F.

Nature. 2018 Jun;558(7711):E4. doi: 10.1038/s41586-018-0113-3.


Chemically controlled aggregation of pluripotent stem cells.

Lipsitz YY, Tonge PD, Zandstra PW.

Biotechnol Bioeng. 2018 Aug;115(8):2061-2066. doi: 10.1002/bit.26719. Epub 2018 May 1.


Convenience versus Biological Significance: Are PMA-Differentiated THP-1 Cells a Reliable Substitute for Blood-Derived Macrophages When Studying in Vitro Polarization?

Tedesco S, De Majo F, Kim J, Trenti A, Trevisi L, Fadini GP, Bolego C, Zandstra PW, Cignarella A, Vitiello L.

Front Pharmacol. 2018 Feb 22;9:71. doi: 10.3389/fphar.2018.00071. eCollection 2018.


Modeling signaling-dependent pluripotency with Boolean logic to predict cell fate transitions.

Yachie-Kinoshita A, Onishi K, Ostblom J, Langley MA, Posfai E, Rossant J, Zandstra PW.

Mol Syst Biol. 2018 Jan 29;14(1):e7952. doi: 10.15252/msb.20177952.


A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies.

Bahr C, von Paleske L, Uslu VV, Remeseiro S, Takayama N, Ng SW, Murison A, Langenfeld K, Petretich M, Scognamiglio R, Zeisberger P, Benk AS, Amit I, Zandstra PW, Lupien M, Dick JE, Trumpp A, Spitz F.

Nature. 2018 Jan 25;553(7689):515-520. doi: 10.1038/nature25193. Epub 2018 Jan 17. Erratum in: Nature. 2018 May 16;:.


Enhanced human hematopoietic stem and progenitor cell engraftment by blocking donor T cell-mediated TNFα signaling.

Wang W, Fujii H, Kim HJ, Hermans K, Usenko T, Xie S, Luo ZJ, Ma J, Celso CL, Dick JE, Schroeder T, Krueger J, Wall D, Egeler RM, Zandstra PW.

Sci Transl Med. 2017 Dec 20;9(421). pii: eaag3214. doi: 10.1126/scitranslmed.aag3214.


FZD4 Marks Lateral Plate Mesoderm and Signals with NORRIN to Increase Cardiomyocyte Induction from Pluripotent Stem Cell-Derived Cardiac Progenitors.

Yoon C, Song H, Yin T, Bausch-Fluck D, Frei AP, Kattman S, Dubois N, Witty AD, Hewel JA, Guo H, Emili A, Wollscheid B, Keller G, Zandstra PW.

Stem Cell Reports. 2018 Jan 9;10(1):87-100. doi: 10.1016/j.stemcr.2017.11.008. Epub 2017 Dec 14.


A stepwise model of reaction-diffusion and positional information governs self-organized human peri-gastrulation-like patterning.

Tewary M, Ostblom J, Prochazka L, Zulueta-Coarasa T, Shakiba N, Fernandez-Gonzalez R, Zandstra PW.

Development. 2017 Dec 1;144(23):4298-4312. doi: 10.1242/dev.149658. Epub 2017 Sep 4.


Steric Hindrance Assay for Secreted Factors in Stem Cell Culture.

Zhou W, Mahshid SS, Wang W, Vallée-Bélisle A, Zandstra PW, Sargent EH, Kelley SO.

ACS Sens. 2017 Apr 28;2(4):495-500. doi: 10.1021/acssensors.7b00136. Epub 2017 Apr 17.


Engineering cell fitness: lessons for regenerative medicine.

Shakiba N, Zandstra PW.

Curr Opin Biotechnol. 2017 Oct;47:7-15. doi: 10.1016/j.copbio.2017.05.005. Epub 2017 May 25. Review.


Engineering the haemogenic niche mitigates endogenous inhibitory signals and controls pluripotent stem cell-derived blood emergence.

Rahman N, Brauer PM, Ho L, Usenko T, Tewary M, Zúñiga-Pflücker JC, Zandstra PW.

Nat Commun. 2017 May 25;8:15380. doi: 10.1038/ncomms15380.


Progenitor T-cell differentiation from hematopoietic stem cells using Delta-like-4 and VCAM-1.

Shukla S, Langley MA, Singh J, Edgar JM, Mohtashami M, Zúñiga-Pflücker JC, Zandstra PW.

Nat Methods. 2017 May;14(5):531-538. doi: 10.1038/nmeth.4258. Epub 2017 Apr 10.


Engineering a humanized bone organ model in mice to study bone metastases.

Martine LC, Holzapfel BM, McGovern JA, Wagner F, Quent VM, Hesami P, Wunner FM, Vaquette C, De-Juan-Pardo EM, Brown TD, Nowlan B, Wu DJ, Hutmacher CO, Moi D, Oussenko T, Piccinini E, Zandstra PW, Mazzieri R, Lévesque JP, Dalton PD, Taubenberger AV, Hutmacher DW.

Nat Protoc. 2017 Apr;12(4):639-663. doi: 10.1038/nprot.2017.002. Epub 2017 Mar 2.


Achieving Efficient Manufacturing and Quality Assurance through Synthetic Cell Therapy Design.

Lipsitz YY, Bedford P, Davies AH, Timmins NE, Zandstra PW.

Cell Stem Cell. 2017 Jan 5;20(1):13-17. doi: 10.1016/j.stem.2016.12.003.


A 17-gene stemness score for rapid determination of risk in acute leukaemia.

Ng SW, Mitchell A, Kennedy JA, Chen WC, McLeod J, Ibrahimova N, Arruda A, Popescu A, Gupta V, Schimmer AD, Schuh AC, Yee KW, Bullinger L, Herold T, Görlich D, Büchner T, Hiddemann W, Berdel WE, Wörmann B, Cheok M, Preudhomme C, Dombret H, Metzeler K, Buske C, Löwenberg B, Valk PJ, Zandstra PW, Minden MD, Dick JE, Wang JC.

Nature. 2016 Dec 15;540(7633):433-437. doi: 10.1038/nature20598. Epub 2016 Dec 7.


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