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Items: 1 to 20 of 144


The optoelectronic microrobot: A versatile toolbox for micromanipulation.

Zhang S, Scott EY, Singh J, Chen Y, Zhang Y, Elsayed M, Chamberlain MD, Shakiba N, Adams K, Yu S, Morshead CM, Zandstra PW, Wheeler AR.

Proc Natl Acad Sci U S A. 2019 Jul 23;116(30):14823-14828. doi: 10.1073/pnas.1903406116. Epub 2019 Jul 9.


Human Embryonic Stem Cell-Derived Cardiomyocytes Regenerate the Infarcted Pig Heart but Induce Ventricular Tachyarrhythmias.

Romagnuolo R, Masoudpour H, Porta-Sánchez A, Qiang B, Barry J, Laskary A, Qi X, Massé S, Magtibay K, Kawajiri H, Wu J, Valdman Sadikov T, Rothberg J, Panchalingam KM, Titus E, Li RK, Zandstra PW, Wright GA, Nanthakumar K, Ghugre NR, Keller G, Laflamme MA.

Stem Cell Reports. 2019 May 14;12(5):967-981. doi: 10.1016/j.stemcr.2019.04.005. Epub 2019 May 2.


Cell competition during reprogramming gives rise to dominant clones.

Shakiba N, Fahmy A, Jayakumaran G, McGibbon S, David L, Trcka D, Elbaz J, Puri MC, Nagy A, van der Kooy D, Goyal S, Wrana JL, Zandstra PW.

Science. 2019 Apr 26;364(6438). pii: eaan0925. doi: 10.1126/science.aan0925. Epub 2019 Mar 21.


Identifying Extrinsic versus Intrinsic Drivers of Variation in Cell Behavior in Human iPSC Lines from Healthy Donors.

Vigilante A, Laddach A, Moens N, Meleckyte R, Leha A, Ghahramani A, Culley OJ, Kathuria A, Hurling C, Vickers A, Wiseman E, Tewary M, Zandstra PW; HipSci Consortium, Durbin R, Fraternali F, Stegle O, Birney E, Luscombe NM, Danovi D, Watt FM.

Cell Rep. 2019 Feb 19;26(8):2078-2087.e3. doi: 10.1016/j.celrep.2019.01.094.


Context-explorer: Analysis of spatially organized protein expression in high-throughput screens.

Ostblom J, Nazareth EJP, Tewary M, Zandstra PW.

PLoS Comput Biol. 2019 Jan 2;15(1):e1006384. doi: 10.1371/journal.pcbi.1006384. eCollection 2019 Jan.


Patterned Optoelectronic Tweezers: A New Scheme for Selecting, Moving, and Storing Dielectric Particles and Cells.

Zhang S, Shakiba N, Chen Y, Zhang Y, Tian P, Singh J, Chamberlain MD, Satkauskas M, Flood AG, Kherani NP, Yu S, Zandstra PW, Wheeler AR.

Small. 2018 Nov;14(45):e1803342. doi: 10.1002/smll.201803342. Epub 2018 Oct 11.


Stem cell bioengineering: building from stem cell biology.

Tewary M, Shakiba N, Zandstra PW.

Nat Rev Genet. 2018 Oct;19(10):595-614. doi: 10.1038/s41576-018-0040-z. Review.


Mechanics-guided developmental fate patterning.

Tewary M, Zandstra PW.

Nat Mater. 2018 Jul;17(7):571-572. doi: 10.1038/s41563-018-0121-6. No abstract available.


Modulating cell state to enhance suspension expansion of human pluripotent stem cells.

Lipsitz YY, Woodford C, Yin T, Hanna JH, Zandstra PW.

Proc Natl Acad Sci U S A. 2018 Jun 19;115(25):6369-6374. doi: 10.1073/pnas.1714099115. Epub 2018 Jun 4.


Author Correction: A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies.

Bahr C, von Paleske L, Uslu VV, Remeseiro S, Takayama N, Ng SW, Murison A, Langenfeld K, Petretich M, Scognamiglio R, Zeisberger P, Benk AS, Amit I, Zandstra PW, Lupien M, Dick JE, Trumpp A, Spitz F.

Nature. 2018 Jun;558(7711):E4. doi: 10.1038/s41586-018-0113-3.


Chemically controlled aggregation of pluripotent stem cells.

Lipsitz YY, Tonge PD, Zandstra PW.

Biotechnol Bioeng. 2018 Aug;115(8):2061-2066. doi: 10.1002/bit.26719. Epub 2018 May 1.


Convenience versus Biological Significance: Are PMA-Differentiated THP-1 Cells a Reliable Substitute for Blood-Derived Macrophages When Studying in Vitro Polarization?

Tedesco S, De Majo F, Kim J, Trenti A, Trevisi L, Fadini GP, Bolego C, Zandstra PW, Cignarella A, Vitiello L.

Front Pharmacol. 2018 Feb 22;9:71. doi: 10.3389/fphar.2018.00071. eCollection 2018.


Modeling signaling-dependent pluripotency with Boolean logic to predict cell fate transitions.

Yachie-Kinoshita A, Onishi K, Ostblom J, Langley MA, Posfai E, Rossant J, Zandstra PW.

Mol Syst Biol. 2018 Jan 29;14(1):e7952. doi: 10.15252/msb.20177952.


A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies.

Bahr C, von Paleske L, Uslu VV, Remeseiro S, Takayama N, Ng SW, Murison A, Langenfeld K, Petretich M, Scognamiglio R, Zeisberger P, Benk AS, Amit I, Zandstra PW, Lupien M, Dick JE, Trumpp A, Spitz F.

Nature. 2018 Jan 25;553(7689):515-520. doi: 10.1038/nature25193. Epub 2018 Jan 17. Erratum in: Nature. 2018 May 16;:.


Enhanced human hematopoietic stem and progenitor cell engraftment by blocking donor T cell-mediated TNFα signaling.

Wang W, Fujii H, Kim HJ, Hermans K, Usenko T, Xie S, Luo ZJ, Ma J, Celso CL, Dick JE, Schroeder T, Krueger J, Wall D, Egeler RM, Zandstra PW.

Sci Transl Med. 2017 Dec 20;9(421). pii: eaag3214. doi: 10.1126/scitranslmed.aag3214.


FZD4 Marks Lateral Plate Mesoderm and Signals with NORRIN to Increase Cardiomyocyte Induction from Pluripotent Stem Cell-Derived Cardiac Progenitors.

Yoon C, Song H, Yin T, Bausch-Fluck D, Frei AP, Kattman S, Dubois N, Witty AD, Hewel JA, Guo H, Emili A, Wollscheid B, Keller G, Zandstra PW.

Stem Cell Reports. 2018 Jan 9;10(1):87-100. doi: 10.1016/j.stemcr.2017.11.008. Epub 2017 Dec 14.


A stepwise model of reaction-diffusion and positional information governs self-organized human peri-gastrulation-like patterning.

Tewary M, Ostblom J, Prochazka L, Zulueta-Coarasa T, Shakiba N, Fernandez-Gonzalez R, Zandstra PW.

Development. 2017 Dec 1;144(23):4298-4312. doi: 10.1242/dev.149658. Epub 2017 Sep 4.


Steric Hindrance Assay for Secreted Factors in Stem Cell Culture.

Zhou W, Mahshid SS, Wang W, Vallée-Bélisle A, Zandstra PW, Sargent EH, Kelley SO.

ACS Sens. 2017 Apr 28;2(4):495-500. doi: 10.1021/acssensors.7b00136. Epub 2017 Apr 17.


Engineering cell fitness: lessons for regenerative medicine.

Shakiba N, Zandstra PW.

Curr Opin Biotechnol. 2017 Oct;47:7-15. doi: 10.1016/j.copbio.2017.05.005. Epub 2017 May 25. Review.


Engineering the haemogenic niche mitigates endogenous inhibitory signals and controls pluripotent stem cell-derived blood emergence.

Rahman N, Brauer PM, Ho L, Usenko T, Tewary M, Zúñiga-Pflücker JC, Zandstra PW.

Nat Commun. 2017 May 25;8:15380. doi: 10.1038/ncomms15380.

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