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Items: 5

1.

Crystal structure of the Frizzled 4 receptor in a ligand-free state.

Yang S, Wu Y, Xu TH, de Waal PW, He Y, Pu M, Chen Y, DeBruine ZJ, Zhang B, Zaidi SA, Popov P, Guo Y, Han GW, Lu Y, Suino-Powell K, Dong S, Harikumar KG, Miller LJ, Katritch V, Xu HE, Shui W, Stevens RC, Melcher K, Zhao S, Xu F.

Nature. 2018 Aug;560(7720):666-670. doi: 10.1038/s41586-018-0447-x. Epub 2018 Aug 22.

PMID:
30135577
2.

CUL5 is required for thalidomide-dependent inhibition of cellular proliferation.

Kunkler B, Salamango D, DeBruine ZJ, Ploch C, Dean S, Grossens D, Hledin MP, Marquez GA, Madden J, Schnell A, Short M, Burnatowska-Hledin MA.

PLoS One. 2018 May 10;13(5):e0196760. doi: 10.1371/journal.pone.0196760. eCollection 2018.

3.

Assembly and architecture of the Wnt/β-catenin signalosome at the membrane.

DeBruine ZJ, Xu HE, Melcher K.

Br J Pharmacol. 2017 Dec;174(24):4564-4574. doi: 10.1111/bph.14048. Epub 2017 Oct 18. Review.

4.

Wnt5a promotes Frizzled-4 signalosome assembly by stabilizing cysteine-rich domain dimerization.

DeBruine ZJ, Ke J, Harikumar KG, Gu X, Borowsky P, Williams BO, Xu W, Miller LJ, Xu HE, Melcher K.

Genes Dev. 2017 May 1;31(9):916-926. doi: 10.1101/gad.298331.117. Epub 2017 May 25.

5.

Nuclear localization signal sequence is required for VACM-1/CUL5-dependent regulation of cellular growth.

Willis AN, Dean SE, Habbouche JA, Kempers BT, Ludwig ML, Sayfie AD, Lewis SP, Harrier S, DeBruine ZJ, Garrett R, Burnatowska-Hledin MA.

Cell Tissue Res. 2017 Apr;368(1):105-114. doi: 10.1007/s00441-016-2522-7. Epub 2016 Nov 11.

PMID:
27834018

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