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Relaxin-2 May Suppress Endometriosis by Reducing Fibrosis, Scar Formation, and Inflammation.
Yoshino O, Ono Y, Honda M, Hattori K, Sato E, Hiraoka T, Ito M, Kobayashi M, Arai K, Katayama H, Tsuchida H, Yamada-Nomoto K, Iwahata S, Fukushi Y, Wada S, Iwase H, Koga K, Osuga Y, Iwaoka M, Unno N. Yoshino O, et al. Among authors: yamada nomoto k. Biomedicines. 2020 Oct 31;8(11):467. doi: 10.3390/biomedicines8110467. Biomedicines. 2020. PMID: 33142814 Free PMC article.
Oral contraceptive therapy reduces serum relaxin-2 in elite female athletes.
Nose-Ogura S, Yoshino O, Yamada-Nomoto K, Nakamura M, Harada M, Dohi M, Okuwaki T, Osuga Y, Kawahara T, Saito S. Nose-Ogura S, et al. Among authors: yamada nomoto k. J Obstet Gynaecol Res. 2017 Mar;43(3):530-535. doi: 10.1111/jog.13226. Epub 2016 Dec 27. J Obstet Gynaecol Res. 2017. PMID: 28026087
PAI-1 in granulosa cells is suppressed directly by statin and indirectly by suppressing TGF-β and TNF-α in mononuclear cells by insulin-sensitizing drugs.
Yamada-Nomoto K, Yoshino O, Akiyama I, Iwase A, Ono Y, Nakamura T, Harada M, Nakashima A, Shima T, Ushijima A, Osuga Y, Chang RJ, Shimasaki S, Saito S. Yamada-Nomoto K, et al. Am J Reprod Immunol. 2017 Jul;78(1):10.1111/aji.12669. doi: 10.1111/aji.12669. Epub 2017 Mar 24. Am J Reprod Immunol. 2017. PMID: 28337819 Free PMC article.