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Items: 1 to 20 of 299

1.

Immune Checkpoint Ligand PD-L1 is Upregulated in Pulmonary Lymphangioleiomyomatosis (LAM).

Maisel K, Merrilees MJ, Atochina-Vasserman EN, Lian L, Obraztsova K, Rue R, Vasserman AN, Zuo N, Angel LF, Gow AJ, Kang I, Wight TN, Eruslanov E, Swartz MA, Krymskaya VP.

Am J Respir Cell Mol Biol. 2018 Aug 10. doi: 10.1165/rcmb.2018-0123OC. [Epub ahead of print]

PMID:
30095976
2.

Asthmatic bronchial epithelial cells promote the establishment of a Hyaluronan-enriched, leukocyte-adhesive extracellular matrix by lung fibroblasts.

Reeves SR, Kang I, Chan CK, Barrow KA, Kolstad TK, White MP, Ziegler SF, Wight TN, Debley JS.

Respir Res. 2018 Aug 2;19(1):146. doi: 10.1186/s12931-018-0849-1.

3.

Clinical factors that influence the cellular responses of saphenous veins used for arterial bypass.

Sobel M, Kikuchi S, Chen L, Tang GL, Wight TN, Kenagy RD.

J Vasc Surg. 2018 Jun 15. pii: S0741-5214(18)31029-2. doi: 10.1016/j.jvs.2018.03.436. [Epub ahead of print]

PMID:
29914830
4.

Smooth muscle glucose metabolism promotes monocyte recruitment and atherosclerosis in a mouse model of metabolic syndrome.

Wall VZ, Barnhart S, Kanter JE, Kramer F, Shimizu-Albergine M, Adhikari N, Wight TN, Hall JL, Bornfeldt KE.

JCI Insight. 2018 Jun 7;3(11). pii: 96544. doi: 10.1172/jci.insight.96544. [Epub ahead of print]

5.

A role for proteoglycans in vascular disease.

Wight TN.

Matrix Biol. 2018 Feb 27. pii: S0945-053X(18)30037-4. doi: 10.1016/j.matbio.2018.02.019. [Epub ahead of print] Review.

PMID:
29499356
6.

Proteoglycans as Immunomodulators of the Innate Immune Response to Lung Infection.

Kang I, Chang MY, Wight TN, Frevert CW.

J Histochem Cytochem. 2018 Apr;66(4):241-259. doi: 10.1369/0022155417751880. Epub 2018 Jan 12.

PMID:
29328866
7.

The biochemistry and immunohistochemistry of versican.

Evanko SP, Chan CK, Johnson PY, Frevert CW, Wight TN.

Methods Cell Biol. 2018;143:261-279. doi: 10.1016/bs.mcb.2017.08.015. Epub 2017 Nov 26.

PMID:
29310782
8.

Hyaluronan content governs tissue stiffness in pancreatic islet inflammation.

Nagy N, de la Zerda A, Kaber G, Johnson PY, Hu KH, Kratochvil MJ, Yadava K, Zhao W, Cui Y, Navarro G, Annes JP, Wight TN, Heilshorn SC, Bollyky PL, Butte MJ.

J Biol Chem. 2018 Jan 12;293(2):567-578. doi: 10.1074/jbc.RA117.000148. Epub 2017 Nov 28.

PMID:
29183997
9.

Versican is produced by Trif- and type I interferon-dependent signaling in macrophages and contributes to fine control of innate immunity in lungs.

Chang MY, Kang I, Gale M Jr, Manicone AM, Kinsella MG, Braun KR, Wigmosta T, Parks WC, Altemeier WA, Wight TN, Frevert CW.

Am J Physiol Lung Cell Mol Physiol. 2017 Dec 1;313(6):L1069-L1086. doi: 10.1152/ajplung.00353.2017. Epub 2017 Sep 14.

PMID:
28912382
10.

Smooth muscle cells of human veins show an increased response to injury at valve sites.

Kikuchi S, Chen L, Xiong K, Saito Y, Azuma N, Tang G, Sobel M, Wight TN, Kenagy RD.

J Vasc Surg. 2018 May;67(5):1556-1570.e9. doi: 10.1016/j.jvs.2017.03.447. Epub 2017 Jun 21.

PMID:
28647196
11.

Microvasculature of the Mouse Cerebral Cortex Exhibits Increased Accumulation and Synthesis of Hyaluronan With Aging.

Reed MJ, Vernon RB, Damodarasamy M, Chan CK, Wight TN, Bentov I, Banks WA.

J Gerontol A Biol Sci Med Sci. 2017 Jun 1;72(6):740-746. doi: 10.1093/gerona/glw213.

12.

A pilot randomised clinical trial of mepolizumab in COPD with eosinophilic bronchitis.

Dasgupta A, Kjarsgaard M, Capaldi D, Radford K, Aleman F, Boylan C, Altman LC, Wight TN, Parraga G, O'Byrne PM, Nair P.

Eur Respir J. 2017 Mar 15;49(3). pii: 1602486. doi: 10.1183/13993003.02486-2016. Print 2017 Mar. No abstract available.

PMID:
28298405
13.

Interplay of extracellular matrix and leukocytes in lung inflammation.

Wight TN, Frevert CW, Debley JS, Reeves SR, Parks WC, Ziegler SF.

Cell Immunol. 2017 Feb;312:1-14. doi: 10.1016/j.cellimm.2016.12.003. Epub 2016 Dec 23. Review.

14.

Crosstalk Between T Lymphocytes and Lung Fibroblasts: Generation of a Hyaluronan-Enriched Extracellular Matrix Adhesive for Monocytes.

Gaucherand L, Falk BA, Evanko SP, Workman G, Chan CK, Wight TN.

J Cell Biochem. 2017 Aug;118(8):2118-2130. doi: 10.1002/jcb.25842. Epub 2017 Apr 18.

15.

Provisional matrix: A role for versican and hyaluronan.

Wight TN.

Matrix Biol. 2017 Jul;60-61:38-56. doi: 10.1016/j.matbio.2016.12.001. Epub 2016 Dec 6. Review.

16.

Interleukin-10-mediated regenerative postnatal tissue repair is dependent on regulation of hyaluronan metabolism via fibroblast-specific STAT3 signaling.

Balaji S, Wang X, King A, Le LD, Bhattacharya SS, Moles CM, Butte MJ, de Jesus Perez VA, Liechty KW, Wight TN, Crombleholme TM, Bollyky PL, Keswani SG.

FASEB J. 2017 Mar;31(3):868-881. doi: 10.1096/fj.201600856R. Epub 2016 Nov 30.

17.

Versican Deficiency Significantly Reduces Lung Inflammatory Response Induced by Polyinosine-Polycytidylic Acid Stimulation.

Kang I, Harten IA, Chang MY, Braun KR, Sheih A, Nivison MP, Johnson PY, Workman G, Kaber G, Evanko SP, Chan CK, Merrilees MJ, Ziegler SF, Kinsella MG, Frevert CW, Wight TN.

J Biol Chem. 2017 Jan 6;292(1):51-63. doi: 10.1074/jbc.M116.753186. Epub 2016 Nov 28.

18.

Versican accumulates in vascular lesions in pulmonary arterial hypertension.

Chang YT, Chan CK, Eriksson I, Johnson PY, Cao X, Westöö C, Norvik C, Andersson-Sjöland A, Westergren-Thorsson G, Johansson S, Hedin U, Kjellén L, Wight TN, Tran-Lundmark K.

Pulm Circ. 2016 Sep;6(3):347-59. doi: 10.1086/686994.

19.

Enhanced T cell responses to IL-6 in type 1 diabetes are associated with early clinical disease and increased IL-6 receptor expression.

Hundhausen C, Roth A, Whalen E, Chen J, Schneider A, Long SA, Wei S, Rawlings R, Kinsman M, Evanko SP, Wight TN, Greenbaum CJ, Cerosaletti K, Buckner JH.

Sci Transl Med. 2016 Sep 14;8(356):356ra119. doi: 10.1126/scitranslmed.aad9943.

20.

The pharmacokinetics and dosing of oral 4-methylumbelliferone for inhibition of hyaluronan synthesis in mice.

Kuipers HF, Nagy N, Ruppert SM, Sunkari VG, Marshall PL, Gebe JA, Ishak HD, Keswani SG, Bollyky J, Frymoyer AR, Wight TN, Steinman L, Bollyky PL.

Clin Exp Immunol. 2016 Sep;185(3):372-81. doi: 10.1111/cei.12815.

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