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Items: 1 to 20 of 152


Activity/exercise-induced changes in the liver transcriptome after chronic spinal cord injury.

Chariker JH, Ohri SS, Gomes C, Brabazon F, Harman KA, DeVeau KM, Magnuson DSK, Hetman M, Petruska JC, Whittemore SR, Rouchka EC.

Sci Data. 2019 Jun 13;6(1):88. doi: 10.1038/s41597-019-0087-5.


Transcriptome of dorsal root ganglia caudal to a spinal cord injury with modulated behavioral activity.

Chariker JH, Gomes C, Brabazon F, Harman KA, Ohri SS, Magnuson DSK, Whittemore SR, Petruska JC, Rouchka EC.

Sci Data. 2019 Jun 7;6(1):83. doi: 10.1038/s41597-019-0088-4.


Autophagy is essential for oligodendrocyte differentiation, survival, and proper myelination.

Bankston AN, Forston MD, Howard RM, Andres KR, Smith AE, Ohri SS, Bates ML, Bunge MB, Whittemore SR.

Glia. 2019 Sep;67(9):1745-1759. doi: 10.1002/glia.23646. Epub 2019 Jun 4.


Following spinal cord injury, PDE4B drives an acute, local inflammatory response and a chronic, systemic response exacerbated by gut dysbiosis and endotoxemia.

Myers SA, Gobejishvili L, Saraswat Ohri S, Garrett Wilson C, Andres KR, Riegler AS, Donde H, Joshi-Barve S, Barve S, Whittemore SR.

Neurobiol Dis. 2019 Apr;124:353-363. doi: 10.1016/j.nbd.2018.12.008. Epub 2018 Dec 14.


Blocking Autophagy in Oligodendrocytes Limits Functional Recovery after Spinal Cord Injury.

Saraswat Ohri S, Bankston AN, Mullins SA, Liu Y, Andres KR, Beare JE, Howard RM, Burke DA, Riegler AS, Smith AE, Hetman M, Whittemore SR.

J Neurosci. 2018 Jun 27;38(26):5900-5912. doi: 10.1523/JNEUROSCI.0679-17.2018. Epub 2018 May 23.


Reversible silencing of lumbar spinal interneurons unmasks a task-specific network for securing hindlimb alternation.

Pocratsky AM, Burke DA, Morehouse JR, Beare JE, Riegler AS, Tsoulfas P, States GJR, Whittemore SR, Magnuson DSK.

Nat Commun. 2017 Dec 6;8(1):1963. doi: 10.1038/s41467-017-02033-x.


Phosphodiesterase 4b expression plays a major role in alcohol-induced neuro-inflammation.

Avila DV, Myers SA, Zhang J, Kharebava G, McClain CJ, Kim HY, Whittemore SR, Gobejishvili L, Barve S.

Neuropharmacology. 2017 Oct;125:376-385. doi: 10.1016/j.neuropharm.2017.08.011. Epub 2017 Aug 12.


The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration.

Xiong G, Hindi SM, Mann AK, Gallot YS, Bohnert KR, Cavener DR, Whittemore SR, Kumar A.

Elife. 2017 Mar 23;6. pii: e22871. doi: 10.7554/eLife.22871.


Pharmacological inhibition of spinal cord injury-stimulated ribosomal biogenesis does not affect locomotor outcome.

Kilanczyk E, Andres KR, Hallgren J, Ohri SS, Laiho M, Whittemore SR, Hetman M.

Neurosci Lett. 2017 Mar 6;642:153-157. doi: 10.1016/j.neulet.2017.02.011. Epub 2017 Feb 7.


Histone deacetylase inhibition is cytotoxic to oligodendrocyte precursor cells in vitro and in vivo.

Dincman TA, Beare JE, Ohri SS, Gallo V, Hetman M, Whittemore SR.

Int J Dev Neurosci. 2016 Nov;54:53-61. doi: 10.1016/j.ijdevneu.2016.08.006. Epub 2016 Aug 29.


Antioxidant Protection of NADPH-Depleted Oligodendrocyte Precursor Cells Is Dependent on Supply of Reduced Glutathione.

Kilanczyk E, Saraswat Ohri S, Whittemore SR, Hetman M.

ASN Neuro. 2016 Jul 21;8(4). pii: 1759091416660404. doi: 10.1177/1759091416660404. Print 2016 Aug.


Does the preclinical evidence for functional remyelination following myelinating cell engraftment into the injured spinal cord support progression to clinical trials?

Myers SA, Bankston AN, Burke DA, Ohri SS, Whittemore SR.

Exp Neurol. 2016 Sep;283(Pt B):560-72. doi: 10.1016/j.expneurol.2016.04.009. Epub 2016 Apr 13. Review.


Remyelinating Oligodendrocyte Precursor Cell miRNAs from the Sfmbt2 Cluster Promote Cell Cycle Arrest and Differentiation.

Kuypers NJ, Bankston AN, Howard RM, Beare JE, Whittemore SR.

J Neurosci. 2016 Feb 3;36(5):1698-710. doi: 10.1523/JNEUROSCI.1240-15.2016.


Activating Transcription Factor-6α Deletion Modulates the Endoplasmic Reticulum Stress Response after Spinal Cord Injury but Does Not Affect Locomotor Recovery.

Saraswat Ohri S, Mullins A, Hetman M, Whittemore SR.

J Neurotrauma. 2018 Feb 1;35(3):486-491. doi: 10.1089/neu.2015.3993. Epub 2017 Nov 1.


Inhibition of GADD34, the stress-inducible regulatory subunit of the endoplasmic reticulum stress response, does not enhance functional recovery after spinal cord injury.

Ohri SS, Mullins A, Hetman M, Whittemore SR.

PLoS One. 2014 Nov 11;9(11):e109703. doi: 10.1371/journal.pone.0109703. eCollection 2014.


Development of a database for translational spinal cord injury research.

Nielson JL, Guandique CF, Liu AW, Burke DA, Lash AT, Moseanko R, Hawbecker S, Strand SC, Zdunowski S, Irvine KA, Brock JH, Nout-Lomas YS, Gensel JC, Anderson KD, Segal MR, Rosenzweig ES, Magnuson DS, Whittemore SR, McTigue DM, Popovich PG, Rabchevsky AG, Scheff SW, Steward O, Courtine G, Edgerton VR, Tuszynski MH, Beattie MS, Bresnahan JC, Ferguson AR.

J Neurotrauma. 2014 Nov 1;31(21):1789-99. doi: 10.1089/neu.2014.3399. Epub 2014 Jul 31.


CD36 deletion improves recovery from spinal cord injury.

Myers SA, Andres KR, Hagg T, Whittemore SR.

Exp Neurol. 2014 Jun;256:25-38. doi: 10.1016/j.expneurol.2014.03.016. Epub 2014 Mar 30.


Restoring endoplasmic reticulum homeostasis improves functional recovery after spinal cord injury.

Ohri SS, Hetman M, Whittemore SR.

Neurobiol Dis. 2013 Oct;58:29-37. doi: 10.1016/j.nbd.2013.04.021. Epub 2013 May 6.


Functional consequences of ethidium bromide demyelination of the mouse ventral spinal cord.

Kuypers NJ, James KT, Enzmann GU, Magnuson DS, Whittemore SR.

Exp Neurol. 2013 Sep;247:615-22. doi: 10.1016/j.expneurol.2013.02.014. Epub 2013 Mar 4.


Consequences of common data analysis inaccuracies in CNS trauma injury basic research.

Burke DA, Whittemore SR, Magnuson DS.

J Neurotrauma. 2013 May 15;30(10):797-805. doi: 10.1089/neu.2012.2704.

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