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Items: 1 to 20 of 48

1.

Genetic architecture of gene expression traits across diverse populations.

Mogil LS, Andaleon A, Badalamenti A, Dickinson SP, Guo X, Rotter JI, Johnson WC, Im HK, Liu Y, Wheeler HE.

PLoS Genet. 2018 Aug 10;14(8):e1007586. doi: 10.1371/journal.pgen.1007586. eCollection 2018 Aug.

2.

Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function.

Wyss AB, Sofer T, Lee MK, Terzikhan N, Nguyen JN, Lahousse L, Latourelle JC, Smith AV, Bartz TM, Feitosa MF, Gao W, Ahluwalia TS, Tang W, Oldmeadow C, Duan Q, de Jong K, Wojczynski MK, Wang XQ, Noordam R, Hartwig FP, Jackson VE, Wang T, Obeidat M, Hobbs BD, Huan T, Gui H, Parker MM, Hu D, Mogil LS, Kichaev G, Jin J, Graff M, Harris TB, Kalhan R, Heckbert SR, Paternoster L, Burkart KM, Liu Y, Holliday EG, Wilson JG, Vonk JM, Sanders JL, Barr RG, de Mutsert R, Menezes AMB, Adams HHH, van den Berge M, Joehanes R, Levin AM, Liberto J, Launer LJ, Morrison AC, Sitlani CM, Celedón JC, Kritchevsky SB, Scott RJ, Christensen K, Rotter JI, Bonten TN, Wehrmeister FC, Bossé Y, Xiao S, Oh S, Franceschini N, Brody JA, Kaplan RC, Lohman K, McEvoy M, Province MA, Rosendaal FR, Taylor KD, Nickle DC, Williams LK, Burchard EG, Wheeler HE, Sin DD, Gudnason V, North KE, Fornage M, Psaty BM, Myers RH, O'Connor G, Hansen T, Laurie CC, Cassano PA, Sung J, Kim WJ, Attia JR, Lange L, Boezen HM, Thyagarajan B, Rich SS, Mook-Kanamori DO, Horta BL, Uitterlinden AG, Im HK, Cho MH, Brusselle GG, Gharib SA, Dupuis J, Manichaikul A, London SJ.

Nat Commun. 2018 Jul 30;9(1):2976. doi: 10.1038/s41467-018-05369-0.

3.

Integration of genetic and functional genomics data to uncover chemotherapeutic induced cytotoxicity.

Li R, Kim D, Wheeler HE, Dudek SM, Dolan ME, Ritchie MD.

Pharmacogenomics J. 2018 May 25. doi: 10.1038/s41397-018-0024-6. [Epub ahead of print]

PMID:
29795408
4.

Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics.

Barbeira AN, Dickinson SP, Bonazzola R, Zheng J, Wheeler HE, Torres JM, Torstenson ES, Shah KP, Garcia T, Edwards TL, Stahl EA, Huckins LM; GTEx Consortium, Nicolae DL, Cox NJ, Im HK.

Nat Commun. 2018 May 8;9(1):1825. doi: 10.1038/s41467-018-03621-1.

5.

Gene-based association study for lipid traits in diverse cohorts implicates BACE1 and SIDT2 regulation in triglyceride levels.

Andaleon A, Mogil LS, Wheeler HE.

PeerJ. 2018 Jan 29;6:e4314. doi: 10.7717/peerj.4314. eCollection 2018.

6.

Application of stem cell derived neuronal cells to evaluate neurotoxic chemotherapy.

Wing C, Komatsu M, Delaney SM, Krause M, Wheeler HE, Dolan ME.

Stem Cell Res. 2017 Jul;22:79-88. doi: 10.1016/j.scr.2017.06.006. Epub 2017 Jun 15.

7.

Clinical and Genome-Wide Analysis of Cisplatin-Induced Peripheral Neuropathy in Survivors of Adult-Onset Cancer.

Dolan ME, El Charif O, Wheeler HE, Gamazon ER, Ardeshir-Rouhani-Fard S, Monahan P, Feldman DR, Hamilton RJ, Vaughn DJ, Beard CJ, Fung C, Kim J, Fossa SD, Hertz DL, Mushiroda T, Kubo M, Einhorn LH, Cox NJ, Travis LB; Platinum Study Group.

Clin Cancer Res. 2017 Oct 1;23(19):5757-5768. doi: 10.1158/1078-0432.CCR-16-3224. Epub 2017 Jun 13.

8.

Genetic Variants Contributing to Colistin Cytotoxicity: Identification of TGIF1 and HOXD10 Using a Population Genomics Approach.

Eadon MT, Hause RJ, Stark AL, Cheng YH, Wheeler HE, Burgess KS, Benson EA, Cunningham PN, Bacallao RL, Dagher PC, Skaar TC, Dolan ME.

Int J Mol Sci. 2017 Mar 18;18(3). pii: E661. doi: 10.3390/ijms18030661.

9.

Variants in WFS1 and Other Mendelian Deafness Genes Are Associated with Cisplatin-Associated Ototoxicity.

Wheeler HE, Gamazon ER, Frisina RD, Perez-Cervantes C, El Charif O, Mapes B, Fossa SD, Feldman DR, Hamilton RJ, Vaughn DJ, Beard CJ, Fung C, Kollmannsberger C, Kim J, Mushiroda T, Kubo M, Ardeshir-Rouhani-Fard S, Einhorn LH, Cox NJ, Dolan ME, Travis LB.

Clin Cancer Res. 2017 Jul 1;23(13):3325-3333. doi: 10.1158/1078-0432.CCR-16-2809. Epub 2016 Dec 30.

10.

Survey of the Heritability and Sparse Architecture of Gene Expression Traits across Human Tissues.

Wheeler HE, Shah KP, Brenner J, Garcia T, Aquino-Michaels K; GTEx Consortium, Cox NJ, Nicolae DL, Im HK.

PLoS Genet. 2016 Nov 11;12(11):e1006423. doi: 10.1371/journal.pgen.1006423. eCollection 2016 Nov.

11.

Comprehensive Audiometric Analysis of Hearing Impairment and Tinnitus After Cisplatin-Based Chemotherapy in Survivors of Adult-Onset Cancer.

Frisina RD, Wheeler HE, Fossa SD, Kerns SL, Fung C, Sesso HD, Monahan PO, Feldman DR, Hamilton R, Vaughn DJ, Beard CJ, Budnick A, Johnson EM, Ardeshir-Rouhani-Fard S, Einhorn LH, Lipshultz SE, Dolan ME, Travis LB.

J Clin Oncol. 2016 Aug 10;34(23):2712-20. doi: 10.1200/JCO.2016.66.8822. Epub 2016 Jun 27.

12.

Pharmacogenetic Discovery in CALGB (Alliance) 90401 and Mechanistic Validation of a VAC14 Polymorphism that Increases Risk of Docetaxel-Induced Neuropathy.

Hertz DL, Owzar K, Lessans S, Wing C, Jiang C, Kelly WK, Patel J, Halabi S, Furukawa Y, Wheeler HE, Sibley AB, Lassiter C, Weisman L, Watson D, Krens SD, Mulkey F, Renn CL, Small EJ, Febbo PG, Shterev I, Kroetz DL, Friedman PN, Mahoney JF, Carducci MA, Kelley MJ, Nakamura Y, Kubo M, Dorsey SG, Dolan ME, Morris MJ, Ratain MJ, McLeod HL.

Clin Cancer Res. 2016 Oct 1;22(19):4890-4900. Epub 2016 May 3.

13.

A gene-based association method for mapping traits using reference transcriptome data.

Gamazon ER, Wheeler HE, Shah KP, Mozaffari SV, Aquino-Michaels K, Carroll RJ, Eyler AE, Denny JC; GTEx Consortium, Nicolae DL, Cox NJ, Im HK.

Nat Genet. 2015 Sep;47(9):1091-8. doi: 10.1038/ng.3367. Epub 2015 Aug 10.

14.

Pharmacoethnicity in Paclitaxel-Induced Sensory Peripheral Neuropathy.

Komatsu M, Wheeler HE, Chung S, Low SK, Wing C, Delaney SM, Gorsic LK, Takahashi A, Kubo M, Kroetz DL, Zhang W, Nakamura Y, Dolan ME.

Clin Cancer Res. 2015 Oct 1;21(19):4337-46. doi: 10.1158/1078-0432.CCR-15-0133. Epub 2015 May 26.

15.

Association of an inherited genetic variant with vincristine-related peripheral neuropathy in children with acute lymphoblastic leukemia.

Diouf B, Crews KR, Lew G, Pei D, Cheng C, Bao J, Zheng JJ, Yang W, Fan Y, Wheeler HE, Wing C, Delaney SM, Komatsu M, Paugh SW, McCorkle JR, Lu X, Winick NJ, Carroll WL, Loh ML, Hunger SP, Devidas M, Pui CH, Dolan ME, Relling MV, Evans WE.

JAMA. 2015 Feb 24;313(8):815-23. doi: 10.1001/jama.2015.0894.

16.

Modeling chemotherapeutic neurotoxicity with human induced pluripotent stem cell-derived neuronal cells.

Wheeler HE, Wing C, Delaney SM, Komatsu M, Dolan ME.

PLoS One. 2015 Feb 17;10(2):e0118020. doi: 10.1371/journal.pone.0118020. eCollection 2015.

17.

Pharmacokinetics and pharmacogenomics of daunorubicin in children: a report from the Children's Oncology Group.

Thompson P, Wheeler HE, Delaney SM, Lorier R, Broeckel U, Devidas M, Reaman GH, Scorsone K, Sung L, Dolan ME, Berg SL.

Cancer Chemother Pharmacol. 2014 Oct;74(4):831-8. doi: 10.1007/s00280-014-2535-4. Epub 2014 Aug 14.

18.

Poly-omic prediction of complex traits: OmicKriging.

Wheeler HE, Aquino-Michaels K, Gamazon ER, Trubetskoy VV, Dolan ME, Huang RS, Cox NJ, Im HK.

Genet Epidemiol. 2014 Jul;38(5):402-15. doi: 10.1002/gepi.21808. Epub 2014 May 2.

19.

Identification of genetic variants associated with capecitabine-induced hand-foot syndrome through integration of patient and cell line genomic analyses.

Wheeler HE, González-Neira A, Pita G, de la Torre-Montero JC, Alonso R, Lopez-Fernandez LA, Alba E, Martín M, Dolan ME.

Pharmacogenet Genomics. 2014 May;24(5):231-7. doi: 10.1097/FPC.0000000000000037.

20.

EPS8 inhibition increases cisplatin sensitivity in lung cancer cells.

Gorsic LK, Stark AL, Wheeler HE, Wong SS, Im HK, Dolan ME.

PLoS One. 2013 Dec 19;8(12):e82220. doi: 10.1371/journal.pone.0082220. eCollection 2013.

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