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Items: 1 to 20 of 58

1.

Prolactin Receptor Signaling Regulates a Pregnancy-Specific Transcriptional Program in Mouse Islets.

Pepin ME, Bickerton HH, Bethea M, Hunter CS, Wende AR, Banerjee RR.

Endocrinology. 2019 May 1;160(5):1150-1163. doi: 10.1210/en.2018-00991.

PMID:
31004482
2.

Epigenetics in the development of diabetic cardiomyopathy.

Pepin ME, Wende AR.

Epigenomics. 2019 Apr;11(5):469-472. doi: 10.2217/epi-2019-0027. Epub 2019 Mar 21. No abstract available.

3.

The Growing Case for Use of SGLT2i in Heart Failure: Additional Benefits of Empagliflozin in a HFpEF Rodent Model.

Ha CM, Wende AR.

JACC Basic Transl Sci. 2019 Feb 25;4(1):38-40. doi: 10.1016/j.jacbts.2019.01.003. eCollection 2019 Feb. No abstract available.

4.

Resident macrophages reprogram toward a developmental state after acute kidney injury.

Lever JM, Hull TD, Boddu R, Pepin ME, Black LM, Adedoyin OO, Yang Z, Traylor AM, Jiang Y, Li Z, Peabody JE, Eckenrode HE, Crossman DK, Crowley MR, Bolisetty S, Zimmerman KA, Wende AR, Mrug M, Yoder BK, Agarwal A, George JF.

JCI Insight. 2019 Jan 24;4(2). pii: 125503. doi: 10.1172/jci.insight.125503. [Epub ahead of print]

5.

Mitoquinone ameliorates pressure overload-induced cardiac fibrosis and left ventricular dysfunction in mice.

Goh KY, He L, Song J, Jinno M, Rogers AJ, Sethu P, Halade GV, Rajasekaran NS, Liu X, Prabhu SD, Darley-Usmar V, Wende AR, Zhou L.

Redox Biol. 2019 Feb;21:101100. doi: 10.1016/j.redox.2019.101100. Epub 2019 Jan 8.

6.

Novel role of the ER/SR Ca2+ sensor STIM1 in the regulation of cardiac metabolism.

Collins HE, Pat BM, Zou L, Litovsky SH, Wende AR, Young ME, Chatham JC.

Am J Physiol Heart Circ Physiol. 2019 May 1;316(5):H1014-H1026. doi: 10.1152/ajpheart.00544.2018. Epub 2018 Dec 21.

PMID:
30575437
7.

Genome-wide DNA methylation encodes cardiac transcriptional reprogramming in human ischemic heart failure.

Pepin ME, Ha CM, Crossman DK, Litovsky SH, Varambally S, Barchue JP, Pamboukian SV, Diakos NA, Drakos SG, Pogwizd SM, Wende AR.

Lab Invest. 2019 Mar;99(3):371-386. doi: 10.1038/s41374-018-0104-x. Epub 2018 Aug 8.

8.

Glucagon Receptor Signaling Regulates Energy Metabolism via Hepatic Farnesoid X Receptor and Fibroblast Growth Factor 21.

Kim T, Nason S, Holleman C, Pepin M, Wilson L, Berryhill TF, Wende AR, Steele C, Young ME, Barnes S, Drucker DJ, Finan B, DiMarchi R, Perez-Tilve D, Tschöp M, Habegger KM.

Diabetes. 2018 Sep;67(9):1773-1782. doi: 10.2337/db17-1502. Epub 2018 Jun 20.

9.

Antiretroviral therapy potentiates high-fat diet induced obesity and glucose intolerance.

Pepin ME, Padgett LE, McDowell RE, Burg AR, Brahma MK, Holleman C, Kim T, Crossman D, Kutsch O, Tse HM, Wende AR, Habegger KM.

Mol Metab. 2018 Jun;12:48-61. doi: 10.1016/j.molmet.2018.04.006. Epub 2018 Apr 20.

10.

Temporal partitioning of adaptive responses of the murine heart to fasting.

Brewer RA, Collins HE, Berry RD, Brahma MK, Tirado BA, Peliciari-Garcia RA, Stanley HL, Wende AR, Taegtmeyer H, Rajasekaran NS, Darley-Usmar V, Zhang J, Frank SJ, Chatham JC, Young ME.

Life Sci. 2018 Mar 15;197:30-39. doi: 10.1016/j.lfs.2018.01.031. Epub 2018 Feb 1.

11.

Gene expression analysis to identify mechanisms underlying heart failure susceptibility in mice and humans.

Koentges C, Pepin ME, Müsse C, Pfeil K, Alvarez SVV, Hoppe N, Hoffmann MM, Odening KE, Sossalla S, Zirlik A, Hein L, Bode C, Wende AR, Bugger H.

Basic Res Cardiol. 2017 Dec 29;113(1):8. doi: 10.1007/s00395-017-0666-6. Print 2018 Jan 8.

12.

Mitochondrial Reactive Oxygen Species in Lipotoxic Hearts Induce Post-Translational Modifications of AKAP121, DRP1, and OPA1 That Promote Mitochondrial Fission.

Tsushima K, Bugger H, Wende AR, Soto J, Jenson GA, Tor AR, McGlauflin R, Kenny HC, Zhang Y, Souvenir R, Hu XX, Sloan CL, Pereira RO, Lira VA, Spitzer KW, Sharp TL, Shoghi KI, Sparagna GC, Rog-Zielinska EA, Kohl P, Khalimonchuk O, Schaffer JE, Abel ED.

Circ Res. 2018 Jan 5;122(1):58-73. doi: 10.1161/CIRCRESAHA.117.311307. Epub 2017 Nov 1.

13.

Metabolic Origins of Heart Failure.

Wende AR, Brahma MK, McGinnis GR, Young ME.

JACC Basic Transl Sci. 2017 Jun;2(3):297-310. doi: 10.1016/j.jacbts.2016.11.009.

14.

Glucose transporter 4-deficient hearts develop maladaptive hypertrophy in response to physiological or pathological stresses.

Wende AR, Kim J, Holland WL, Wayment BE, O'Neill BT, Tuinei J, Brahma MK, Pepin ME, McCrory MA, Luptak I, Halade GV, Litwin SE, Abel ED.

Am J Physiol Heart Circ Physiol. 2017 Dec 1;313(6):H1098-H1108. doi: 10.1152/ajpheart.00101.2017. Epub 2017 Aug 19.

15.

Genetic disruption of the cardiomyocyte circadian clock differentially influences insulin-mediated processes in the heart.

McGinnis GR, Tang Y, Brewer RA, Brahma MK, Stanley HL, Shanmugam G, Rajasekaran NS, Rowe GC, Frank SJ, Wende AR, Abel ED, Taegtmeyer H, Litovsky S, Darley-Usmar V, Zhang J, Chatham JC, Young ME.

J Mol Cell Cardiol. 2017 Sep;110:80-95. doi: 10.1016/j.yjmcc.2017.07.005. Epub 2017 Jul 20.

16.

Diabetes-Related Cardiac Dysfunction.

Williams LJ, Nye BG, Wende AR.

Endocrinol Metab (Seoul). 2017 Jun;32(2):171-179. doi: 10.3803/EnM.2017.32.2.171. Review.

17.

O-GlcNAcylation and cardiovascular disease.

Wright JN, Collins HE, Wende AR, Chatham JC.

Biochem Soc Trans. 2017 Apr 15;45(2):545-553. doi: 10.1042/BST20160164. Review.

18.

My Sweetheart Is Broken: Role of Glucose in Diabetic Cardiomyopathy.

Brahma MK, Pepin ME, Wende AR.

Diabetes Metab J. 2017 Feb;41(1):1-9. doi: 10.4093/dmj.2017.41.1.1. Review.

19.

Redox biology and the interface between bioenergetics, autophagy and circadian control of metabolism.

Wende AR, Young ME, Chatham J, Zhang J, Rajasekaran NS, Darley-Usmar VM.

Free Radic Biol Med. 2016 Nov;100:94-107. doi: 10.1016/j.freeradbiomed.2016.05.022. Epub 2016 May 27. Review.

20.

Phosphoinositide dependent protein kinase 1 is required for exercise-induced cardiac hypertrophy but not the associated mitochondrial adaptations.

Noh J, Wende AR, Olsen CD, Kim B, Bevins J, Zhu Y, Zhang QJ, Riehle C, Abel ED.

J Mol Cell Cardiol. 2015 Dec;89(Pt B):297-305. doi: 10.1016/j.yjmcc.2015.10.015. Epub 2015 Oct 22.

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