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Items: 1 to 20 of 408

1.

Selection of antimicrobial frog peptides and temporin-1DRa analogs for treatment of bacterial infections based on their cytotoxicity and differential activity against pathogens.

Gaiser RA, Ayerra Mangado J, Mechkarska M, Kaman WE, van Baarlen P, Conlon JM, Wells JM.

Chem Biol Drug Des. 2019 May 18. doi: 10.1111/cbdd.13569. [Epub ahead of print]

PMID:
31102497
2.

Fibroblast Growth Factor 23 is Associated with a Frequent Exacerbator Phenotype in COPD: A Cross-Sectional Pilot Study.

Gulati S, Wells JM, Urdaneta GP, Balestrini K, Vital I, Tovar K, Barnes JW, Bhatt SP, Campos M, Krick S.

Int J Mol Sci. 2019 May 9;20(9). pii: E2292. doi: 10.3390/ijms20092292.

3.

Differentiation of Human Pluripotent Stem Cells into Colonic Organoids via Transient Activation of BMP Signaling.

Múnera JO, Sundaram N, Rankin SA, Hill D, Watson C, Mahe M, Vallance JE, Shroyer NF, Sinagoga KL, Zarzoso-Lacoste A, Hudson JR, Howell JC, Chatuvedi P, Spence JR, Shannon JM, Zorn AM, Helmrath MA, Wells JM.

Cell Stem Cell. 2019 May 2;24(5):829. doi: 10.1016/j.stem.2019.04.002. No abstract available.

4.

Proline-Glycine-Proline Peptides Are Critical in the Development of Smoke-Induced Emphysema.

Abdul Roda M, Xu X, Abdalla TH, Sadik M, Szul T, Bratcher PE, Viera L, Solomon GM, Wells JM, McNicholas CM, Redegeld FA, Folkerts G, Blalock JE, Gaggar A.

Am J Respir Cell Mol Biol. 2019 Apr 8. doi: 10.1165/rcmb.2018-0216OC. [Epub ahead of print]

PMID:
30958968
5.

In vivo transcriptomes of Streptococcus suis reveal genes required for niche-specific adaptation and pathogenesis.

Arenas J, Bossers-de Vries R, Harders-Westerveen J, Buys H, Ruuls-van Stalle LMF, Stockhofe-Zurwieden N, Zaccaria E, Tommassen J, Wells JM, Smith HE, de Greeff A.

Virulence. 2019 Dec;10(1):334-351. doi: 10.1080/21505594.2019.1599669.

PMID:
30957693
6.

Pathotyping the Zoonotic Pathogen Streptococcus suis: Novel Genetic Markers to Differentiate Invasive Disease-Associated Isolates from Non-Disease Associated Isolates from England and Wales.

Wileman TM, Weinert LA, Howell KJ, Wang J, Peters SE, Williamson SM, Wells JM, Rycroft AN, Wren BW, Maskell DJ, Tucker AW; BRaDP1T Consortium.

J Clin Microbiol. 2019 Apr 3. pii: JCM.01712-18. doi: 10.1128/JCM.01712-18. [Epub ahead of print]

7.

From Discovery to Practice and Survivorship: Building a National Real-World Data Learning Healthcare Framework for Military and Veteran Cancer Patients.

Lee JSH, Darcy KM, Hu H, Casablanca Y, Conrads TP, Dalgard CL, Freymann JB, Hanlon SE, Huang GD, Kvecher L, Maxwell GL, Meng F, Moncur JT, Turner C, Wells JM, Wilkerson MD, Zhu K, Ramoni RB, Shriver CD.

Clin Pharmacol Ther. 2019 Mar 5. doi: 10.1002/cpt.1425. [Epub ahead of print] No abstract available.

PMID:
30838639
8.

Phenotype Detection Registry System (PheDRS) - Implementation of a Generalizable Single Institution Clinical Registry Architecture.

Osborne JD, Khare A, Dempsey DM, Wells JM, Wyatt M, Gordon G, Liang WH, Cimino J.

AMIA Annu Symp Proc. 2018 Dec 5;2018:847-856. eCollection 2018.

9.

Exopolysaccharides synthesized by Bifidobacterium animalis subsp. lactis interact with TLR4 in intestinal epithelial cells.

Castro-Bravo N, Margolles A, Wells JM, Ruas-Madiedo P.

Anaerobe. 2019 Apr;56:98-101. doi: 10.1016/j.anaerobe.2019.02.014. Epub 2019 Feb 20.

PMID:
30794874
10.

Arterial Vascular Pruning, Right Ventricular Size and Clinical Outcomes in COPD.

Washko GR, Nardelli P, Ash SY, Vegas Sanchez-Ferrero G, Rahaghi FN, Come CE, Dransfield MT, Kalhan R, Han MK, Bhatt S, Wells JM, Aaron CP, Diaz AA, Ross JC, Cuttica MJ, Labaki WW, Querejeta Roca G, Shah AM, Young K, Kinney GL, Hokanson JE, Agusti A, San José Estépar R; COPDGene Investigators.

Am J Respir Crit Care Med. 2019 Feb 13. doi: 10.1164/rccm.201811-2063OC. [Epub ahead of print]

PMID:
30758975
11.

Lactobacillus mucosae DPC 6426 as a bile-modifying and immunomodulatory microbe.

Ryan PM, Stolte EH, London LEE, Wells JM, Long SL, Joyce SA, Gahan CGM, Fitzgerald GF, Ross RP, Caplice NM, Stanton C.

BMC Microbiol. 2019 Feb 8;19(1):33. doi: 10.1186/s12866-019-1403-0.

12.

Anemia and Adverse Outcomes in a Chronic Obstructive Pulmonary Disease Population with a High Burden of Comorbidities. An Analysis from SPIROMICS.

Putcha N, Fawzy A, Paul GG, Lambert AA, Psoter KJ, Sidhaye VK, Woo J, Wells JM, Labaki WW, Doerschuk CM, Kanner RE, Han MK, Martinez C, Paulin LM, Martinez FJ, Wise RA, O'Neal WK, Barr RG, Hansel NN; SPIROMICS investigators.

Ann Am Thorac Soc. 2018 Jun;15(6):710-717. doi: 10.1513/AnnalsATS.201708-687OC.

PMID:
30726108
13.

Age-associated Impairment of the Mucus Barrier Function is Associated with Profound Changes in Microbiota and Immunity.

Sovran B, Hugenholtz F, Elderman M, Van Beek AA, Graversen K, Huijskes M, Boekschoten MV, Savelkoul HFJ, De Vos P, Dekker J, Wells JM.

Sci Rep. 2019 Feb 5;9(1):1437. doi: 10.1038/s41598-018-35228-3.

14.

Increased Programmed Death-Ligand 1 is an Early Epithelial Cell Response to Helicobacter pylori Infection.

Holokai L, Chakrabarti J, Broda T, Chang J, Hawkins JA, Sundaram N, Wroblewski LE, Peek RM Jr, Wang J, Helmrath M, Wells JM, Zavros Y.

PLoS Pathog. 2019 Jan 31;15(1):e1007468. doi: 10.1371/journal.ppat.1007468. eCollection 2019 Jan.

15.

Safety and Tolerability of Comprehensive Research Bronchoscopy in Chronic Obstructive Pulmonary Disease. Results from the SPIROMICS Bronchoscopy Substudy.

Wells JM, Arenberg DA, Barjaktarevic I, Bhatt SP, Bowler RP, Christenson SA, Couper DJ, Dransfield MT, Han MK, Hoffman EA, Kaner RJ, Kim V, Kleerup E, Martinez FJ, Moore WC, O'Beirne SL, Paine R 3rd, Putcha N, Raman SM, Barr RG, Rennard SI, Woodruff PG, Curtis JL.

Ann Am Thorac Soc. 2019 Apr;16(4):439-446. doi: 10.1513/AnnalsATS.201807-441OC.

PMID:
30653926
16.

Activated PMN Exosomes: Pathogenic Entities Causing Matrix Destruction and Disease in the Lung.

Genschmer KR, Russell DW, Lal C, Szul T, Bratcher PE, Noerager BD, Abdul Roda M, Xu X, Rezonzew G, Viera L, Dobosh BS, Margaroli C, Abdalla TH, King RW, McNicholas CM, Wells JM, Dransfield MT, Tirouvanziam R, Gaggar A, Blalock JE.

Cell. 2019 Jan 10;176(1-2):113-126.e15. doi: 10.1016/j.cell.2018.12.002.

PMID:
30633902
17.

Generation of human antral and fundic gastric organoids from pluripotent stem cells.

Broda TR, McCracken KW, Wells JM.

Nat Protoc. 2019 Jan;14(1):28-50. doi: 10.1038/s41596-018-0080-z.

PMID:
30470820
18.

Inflammation and endothelial activation in early adulthood are associated with future emphysema: the CARDIA Lung Study.

Wells JM, Colangelo LA, Sivarajan L, Thyagarajan B, Dransfield MT, Iribarren C, Reyfman PA, Jacobs DR, Washko GR, Kalhan R.

Eur Respir J. 2019 Jan 17;53(1). pii: 1801532. doi: 10.1183/13993003.01532-2018. Print 2019 Jan. No abstract available.

PMID:
30464011
19.

Polyphenols and Tryptophan Metabolites Activate the Aryl Hydrocarbon Receptor in an in vitro Model of Colonic Fermentation.

Koper JEB, Loonen LMP, Wells JM, Troise AD, Capuano E, Fogliano V.

Mol Nutr Food Res. 2019 Feb;63(3):e1800722. doi: 10.1002/mnfr.201800722. Epub 2018 Nov 28.

PMID:
30443985
20.

Elevated circulating MMP-9 is linked to increased COPD exacerbation risk in SPIROMICS and COPDGene.

Wells JM, Parker MM, Oster RA, Bowler RP, Dransfield MT, Bhatt SP, Cho MH, Kim V, Curtis JL, Martinez FJ, Paine R 3rd, O'Neal W, Labaki WW, Kaner RJ, Barjaktarevic I, Han MK, Silverman EK, Crapo JD, Barr RG, Woodruff P, Castaldi PJ, Gaggar A, Investigators TSAC.

JCI Insight. 2018 Nov 15;3(22). pii: 123614. doi: 10.1172/jci.insight.123614.

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