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Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.
Müller PM, Rademacher J, Bagshaw RD, Wortmann C, Barth C, van Unen J, Alp KM, Giudice G, Eccles RL, Heinrich LE, Pascual-Vargas P, Sanchez-Castro M, Brandenburg L, Mbamalu G, Tucholska M, Spatt L, Czajkowski MT, Welke RW, Zhang S, Nguyen V, Rrustemi T, Trnka P, Freitag K, Larsen B, Popp O, Mertins P, Gingras AC, Roth FP, Colwill K, Bakal C, Pertz O, Pawson T, Petsalaki E, Rocks O. Müller PM, et al. Among authors: welke rw. Nat Cell Biol. 2020 Apr;22(4):498-511. doi: 10.1038/s41556-020-0488-x. Epub 2020 Mar 23. Nat Cell Biol. 2020. PMID: 32203420
RNAi-based small molecule repositioning reveals clinically approved urea-based kinase inhibitors as broadly active antivirals.
Lesch M, Luckner M, Meyer M, Weege F, Gravenstein I, Raftery M, Sieben C, Martin-Sancho L, Imai-Matsushima A, Welke RW, Frise R, Barclay W, Schönrich G, Herrmann A, Meyer TF, Karlas A. Lesch M, et al. Among authors: welke rw. PLoS Pathog. 2019 Mar 18;15(3):e1007601. doi: 10.1371/journal.ppat.1007601. eCollection 2019 Mar. PLoS Pathog. 2019. PMID: 30883607 Free PMC article.
Genetic characterization of an adapted pandemic 2009 H1N1 influenza virus that reveals improved replication rates in human lung epithelial cells.
Wörmann X, Lesch M, Welke RW, Okonechnikov K, Abdurishid M, Sieben C, Geissner A, Brinkmann V, Kastner M, Karner A, Zhu R, Hinterdorfer P, Anish C, Seeberger PH, Herrmann A, Meyer TF, Karlas A. Wörmann X, et al. Among authors: welke rw. Virology. 2016 May;492:118-29. doi: 10.1016/j.virol.2016.02.002. Epub 2016 Feb 23. Virology. 2016. PMID: 26914510 Free article.