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Items: 1 to 20 of 25

1.

Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress.

Hagen TM, Liu J, Lykkesfeldt J, Wehr CM, Ingersoll RT, Vinarsky V, Bartholomew JC, Ames BN.

Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):1870-5. Erratum in: Proc Natl Acad Sci U S A 2002 May 14;99(10):7184.

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3.

Micronucleated erythrocyte frequency in peripheral blood of B6C3F(1) mice from short-term, prechronic, and chronic studies of the NTP carcinogenesis bioassay program.

Witt KL, Knapton A, Wehr CM, Hook GJ, Mirsalis J, Shelby MD, MacGregor JT.

Environ Mol Mutagen. 2000;36(3):163-94.

PMID:
11044899
4.

(R)-alpha-lipoic acid-supplemented old rats have improved mitochondrial function, decreased oxidative damage, and increased metabolic rate.

Hagen TM, Ingersoll RT, Lykkesfeldt J, Liu J, Wehr CM, Vinarsky V, Bartholomew JC, Ames AB.

FASEB J. 1999 Feb;13(2):411-8.

PMID:
9973329
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6.

Acetyl-L-carnitine fed to old rats partially restores mitochondrial function and ambulatory activity.

Hagen TM, Ingersoll RT, Wehr CM, Lykkesfeldt J, Vinarsky V, Bartholomew JC, Song MH, Ames BN.

Proc Natl Acad Sci U S A. 1998 Aug 4;95(16):9562-6.

7.

'Spontaneous' genetic damage in man: evaluation of interindividual variability, relationship among markers of damage, and influence of nutritional status.

MacGregor JT, Wehr CM, Hiatt RA, Peters B, Tucker JD, Langlois RG, Jacob RA, Jensen RH, Yager JW, Shigenaga MK, Frei B, Eynon BP, Ames BN.

Mutat Res. 1997 Jun 9;377(1):125-35.

PMID:
9219587
8.

Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal damage.

Blount BC, Mack MM, Wehr CM, MacGregor JT, Hiatt RA, Wang G, Wickramasinghe SN, Everson RB, Ames BN.

Proc Natl Acad Sci U S A. 1997 Apr 1;94(7):3290-5.

9.

Mitochondrial decay in hepatocytes from old rats: membrane potential declines, heterogeneity and oxidants increase.

Hagen TM, Yowe DL, Bartholomew JC, Wehr CM, Do KL, Park JY, Ames BN.

Proc Natl Acad Sci U S A. 1997 Apr 1;94(7):3064-9.

10.

Extensive oxidative DNA damage in hepatocytes of transgenic mice with chronic active hepatitis destined to develop hepatocellular carcinoma.

Hagen TM, Huang S, Curnutte J, Fowler P, Martinez V, Wehr CM, Ames BN, Chisari FV.

Proc Natl Acad Sci U S A. 1994 Dec 20;91(26):12808-12.

11.

Assay of excised oxidative DNA lesions: isolation of 8-oxoguanine and its nucleoside derivatives from biological fluids with a monoclonal antibody column.

Park EM, Shigenaga MK, Degan P, Korn TS, Kitzler JW, Wehr CM, Kolachana P, Ames BN.

Proc Natl Acad Sci U S A. 1992 Apr 15;89(8):3375-9.

12.

Cytogenetic damage induced by folate deficiency in mice is enhanced by caffeine.

MacGregor JT, Schlegel R, Wehr CM, Alperin P, Ames BN.

Proc Natl Acad Sci U S A. 1990 Dec;87(24):9962-5.

13.

Micronucleated erythrocytes as an index of cytogenetic damage in humans: demographic and dietary factors associated with micronucleated erythrocytes in splenectomized subjects.

Smith DF, MacGregor JT, Hiatt RA, Hooper NK, Wehr CM, Peters B, Goldman LR, Yuan LA, Smith PA, Becker CE.

Cancer Res. 1990 Aug 15;50(16):5049-54.

14.

Effect of repeated benzene inhalation exposures on benzene metabolism, binding to hemoglobin, and induction of micronuclei.

Sabourin PJ, Sun JD, MacGregor JT, Wehr CM, Birnbaum LS, Lucier G, Henderson RF.

Toxicol Appl Pharmacol. 1990 May;103(3):452-62.

PMID:
2339418
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16.

Non-clastogenicity in mouse bone marrow of fructose/lysine and other sugar/amino acid browning products with in vitro genotoxicity.

MacGregor JT, Tucker JD, Ziderman II, Wehr CM, Wilson RE, Friedman M.

Food Chem Toxicol. 1989 Nov;27(11):715-21.

PMID:
2515134
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19.

1,3-Butadiene: induction of micronucleated erythrocytes in the peripheral blood of B6C3F1 mice exposed by inhalation for 13 weeks.

Jauhar PP, Henika PR, MacGregor JT, Wehr CM, Shelby MD, Murphy SA, Margolin BH.

Mutat Res. 1988 Nov-Dec;209(3-4):171-6. No abstract available.

PMID:
3193981
20.

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