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Items: 1 to 20 of 122

1.

WWP1 Inhibition Rescues PTEN Tumor-Suppressive Activity.

[No authors listed]

Cancer Discov. 2019 May 24. doi: 10.1158/2159-8290.CD-RW2019-080. [Epub ahead of print]

PMID:
31126991
2.

Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway.

Lee YR, Chen M, Lee JD, Zhang J, Lin SY, Fu TM, Chen H, Ishikawa T, Chiang SY, Katon J, Zhang Y, Shulga YV, Bester AC, Fung J, Monteleone E, Wan L, Shen C, Hsu CH, Papa A, Clohessy JG, Teruya-Feldstein J, Jain S, Wu H, Matesic L, Chen RH, Wei W, Pandolfi PP.

Science. 2019 May 17;364(6441). pii: eaau0159. doi: 10.1126/science.aau0159.

PMID:
31097636
3.

A positive feedback loop of miR-30a-5p-WWP1-NF-κB in the regulation of glioma development.

Zhao P, Wang M, An J, Sun H, Li T, Li D.

Int J Biochem Cell Biol. 2019 Jul;112:39-49. doi: 10.1016/j.biocel.2019.04.003. Epub 2019 Apr 10.

PMID:
30978403
4.

Hyperglycemia induces skeletal muscle atrophy via a WWP1/KLF15 axis.

Hirata Y, Nomura K, Senga Y, Okada Y, Kobayashi K, Okamoto S, Minokoshi Y, Imamura M, Takeda S, Hosooka T, Ogawa W.

JCI Insight. 2019 Feb 21;4(4). pii: 124952. doi: 10.1172/jci.insight.124952. eCollection 2019 Feb 21.

5.

Identification of WWP1 as an obesity-associated E3 ubiquitin ligase with a protective role against oxidative stress in adipocytes.

Kobayashi M, Hoshino S, Abe T, Okita N, Tagawa R, Nagai W, Konno R, Suzuki Y, Furuya K, Ishikawa N, Okado H, Oku M, Iwamoto M, Miura Y, Sudo Y, Higami Y.

Biochem Biophys Res Commun. 2019 Jan 1;508(1):117-122. doi: 10.1016/j.bbrc.2018.11.127. Epub 2018 Nov 22.

6.

miR-129-5p and -3p co-target WWP1 to suppress gastric cancer proliferation and migration.

Ma L, Chen X, Li C, Cheng R, Gao Z, Meng X, Sun C, Liang C, Liu Y.

J Cell Biochem. 2018 Nov 11. doi: 10.1002/jcb.28027. [Epub ahead of print]

PMID:
30417502
7.

Polarity Acquisition in Cortical Neurons Is Driven by Synergistic Action of Sox9-Regulated Wwp1 and Wwp2 E3 Ubiquitin Ligases and Intronic miR-140.

Ambrozkiewicz MC, Schwark M, Kishimoto-Suga M, Borisova E, Hori K, Salazar-Lázaro A, Rusanova A, Altas B, Piepkorn L, Bessa P, Schaub T, Zhang X, Rabe T, Ripamonti S, Rosário M, Akiyama H, Jahn O, Kobayashi T, Hoshino M, Tarabykin V, Kawabe H.

Neuron. 2018 Dec 5;100(5):1097-1115.e15. doi: 10.1016/j.neuron.2018.10.008. Epub 2018 Nov 1.

PMID:
30392800
8.

WW domain-mediated regulation and activation of E3 ubiquitin ligase Suppressor of Deltex.

Yao W, Shan Z, Gu A, Fu M, Shi Z, Wen W.

J Biol Chem. 2018 Oct 26;293(43):16697-16708. doi: 10.1074/jbc.RA118.003781. Epub 2018 Sep 13.

PMID:
30213861
9.

Protein kinase CK2 activation is required for transforming growth factor β-induced epithelial-mesenchymal transition.

Kim S, Ham S, Yang K, Kim K.

Mol Oncol. 2018 Oct;12(10):1811-1826. doi: 10.1002/1878-0261.12378. Epub 2018 Sep 21.

10.
11.

β-dystroglycan is regulated by a balance between WWP1-mediated degradation and protection from WWP1 by dystrophin and utrophin.

Cho EB, Yoo W, Yoon SK, Yoon JB.

Biochim Biophys Acta Mol Basis Dis. 2018 Jun;1864(6 Pt A):2199-2213. doi: 10.1016/j.bbadis.2018.04.001. Epub 2018 Apr 7.

12.

Selection and Characterization of a DNA Aptamer Specifically Targeting Human HECT Ubiquitin Ligase WWP1.

Tucker WO, Kinghorn AB, Fraser LA, Cheung YW, Tanner JA.

Int J Mol Sci. 2018 Mar 7;19(3). pii: E763. doi: 10.3390/ijms19030763.

13.
14.

The E3 ubiquitin ligase WWP1 sustains the growth of acute myeloid leukaemia.

Sanarico AG, Ronchini C, Croce A, Memmi EM, Cammarata UA, De Antoni A, Lavorgna S, Divona M, Giacò L, Melloni GEM, Brendolan A, Simonetti G, Martinelli G, Mancuso P, Bertolini F, Coco FL, Melino G, Pelicci PG, Bernassola F.

Leukemia. 2018 Apr;32(4):911-919. doi: 10.1038/leu.2017.342. Epub 2017 Dec 6.

15.

Ubiquitin Ligase WWP1 Interacts with Ebola Virus VP40 To Regulate Egress.

Han Z, Sagum CA, Takizawa F, Ruthel G, Berry CT, Kong J, Sunyer JO, Freedman BD, Bedford MT, Sidhu SS, Sudol M, Harty RN.

J Virol. 2017 Sep 27;91(20). pii: e00812-17. doi: 10.1128/JVI.00812-17. Print 2017 Oct 15.

16.

The muscular dystrophic chicken is hypernatremic.

Saito N, Hirayama H, Yoshimura K, Atsumi Y, Mizutani M, Kinoshita K, Fujiwara A, Namikawa T.

Br Poult Sci. 2017 Oct;58(5):506-511. doi: 10.1080/00071668.2017.1354356. Epub 2017 Jul 17.

PMID:
28692350
17.

Controlled and sustained delivery of siRNA/NPs from hydrogels expedites bone fracture healing.

Wang Y, Malcolm DW, Benoit DSW.

Biomaterials. 2017 Sep;139:127-138. doi: 10.1016/j.biomaterials.2017.06.001. Epub 2017 Jun 4.

18.

A Tunable Brake for HECT Ubiquitin Ligases.

Chen Z, Jiang H, Xu W, Li X, Dempsey DR, Zhang X, Devreotes P, Wolberger C, Amzel LM, Gabelli SB, Cole PA.

Mol Cell. 2017 May 4;66(3):345-357.e6. doi: 10.1016/j.molcel.2017.03.020.

19.

Mechanism of ubiquitin chain synthesis employed by a HECT domain ubiquitin ligase.

French ME, Klosowiak JL, Aslanian A, Reed SI, Yates JR 3rd, Hunter T.

J Biol Chem. 2017 Jun 23;292(25):10398-10413. doi: 10.1074/jbc.M117.789479. Epub 2017 May 1.

20.

Overexpression of miR-584-5p inhibits proliferation and induces apoptosis by targeting WW domain-containing E3 ubiquitin protein ligase 1 in gastric cancer.

Li Q, Li Z, Wei S, Wang W, Chen Z, Zhang L, Chen L, Li B, Sun G, Xu J, Li Q, Wang L, Xu Z, Xia Y, Zhang D, Xu H, Xu Z.

J Exp Clin Cancer Res. 2017 Apr 21;36(1):59. doi: 10.1186/s13046-017-0532-2.

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