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Human somatic PTPN11 mutations induce hematopoietic-cell hypersensitivity to granulocyte-macrophage colony-stimulating factor.
Blood. 2005 May 1;105(9):3737-42. doi: 10.1182/blood-2004-10-4002. Epub 2005 Jan 11.
Blood. 2005.
PMID: 15644411
Free PMC article.
Shp-2 heterozygous hematopoietic stem cells have deficient repopulating ability due to diminished self-renewal.
Chan RJ, Li Y, Hass MN, Walter A, Voorhorst CS, Shelley WC, Yang Z, Orschell CM, Yoder MC.
Chan RJ, et al. Among authors: voorhorst cs.
Exp Hematol. 2006 Sep;34(9):1230-9. doi: 10.1016/j.exphem.2006.04.017.
Exp Hematol. 2006.
PMID: 16939816
Free article.
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Increased c-Jun expression and reduced GATA2 expression promote aberrant monocytic differentiation induced by activating PTPN11 mutants.
Yang Z, Kondo T, Voorhorst CS, Nabinger SC, Ndong L, Yin F, Chan EM, Yu M, Würstlin O, Kratz CP, Niemeyer CM, Flotho C, Hashino E, Chan RJ.
Yang Z, et al. Among authors: voorhorst cs.
Mol Cell Biol. 2009 Aug;29(16):4376-93. doi: 10.1128/MCB.01330-08. Epub 2009 Jun 15.
Mol Cell Biol. 2009.
PMID: 19528235
Free PMC article.
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