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Items: 1 to 20 of 144

1.

Changes of dimension of EEG/ECoG nonlinear dynamics predict epileptogenesis and therapy outcomes.

Rizzi M, Brandt C, Weissberg I, Milikovsky DZ, Pauletti A, Terrone G, Salamone A, Frigerio F, Löscher W, Friedman A, Vezzani A.

Neurobiol Dis. 2018 Dec 24;124:373-378. doi: 10.1016/j.nbd.2018.12.014. [Epub ahead of print]

PMID:
30590177
2.

Pharmacological targeting of brain inflammation in epilepsy: Therapeutic perspectives from experimental and clinical studies.

Ravizza T, Vezzani A.

Epilepsia Open. 2018 Jul 16;3(Suppl Suppl 2):133-142. doi: 10.1002/epi4.12242. eCollection 2018 Dec.

3.

n-3 Docosapentaenoic acid-derived protectin D1 promotes resolution of neuroinflammation and arrests epileptogenesis.

Frigerio F, Pasqualini G, Craparotta I, Marchini S, van Vliet EA, Foerch P, Vandenplas C, Leclercq K, Aronica E, Porcu L, Pistorius K, Colas RA, Hansen TV, Perretti M, Kaminski RM, Dalli J, Vezzani A.

Brain. 2018 Nov 1;141(11):3130-3143. doi: 10.1093/brain/awy247.

4.

Oxidative stress and inflammation in a spectrum of epileptogenic cortical malformations: molecular insights into their interdependence.

Arena A, Zimmer TS, van Scheppingen J, Korotkov A, Anink JJ, Mühlebner A, Jansen FE, van Hecke W, Spliet WG, van Rijen PC, Vezzani A, Baayen JC, Idema S, Iyer AM, Perluigi M, Mills JD, van Vliet EA, Aronica E.

Brain Pathol. 2018 Oct 10. doi: 10.1111/bpa.12661. [Epub ahead of print]

PMID:
30303592
5.

Epilepsy.

Devinsky O, Vezzani A, O'Brien TJ, Jette N, Scheffer IE, de Curtis M, Perucca P.

Nat Rev Dis Primers. 2018 May 3;4:18024. doi: 10.1038/nrdp.2018.24. Review.

PMID:
29722352
6.

Intrinsic Inflammation Is a Potential Anti-Epileptogenic Target in the Organotypic Hippocampal Slice Model.

Chong SA, Balosso S, Vandenplas C, Szczesny G, Hanon E, Claes K, Van Damme X, Danis B, Van Eyll J, Wolff C, Vezzani A, Kaminski RM, Niespodziany I.

Neurotherapeutics. 2018 Apr;15(2):470-488. doi: 10.1007/s13311-018-0607-6.

7.

Neuroinflammation Alters Integrative Properties of Rat Hippocampal Pyramidal Cells.

Frigerio F, Flynn C, Han Y, Lyman K, Lugo JN, Ravizza T, Ghestem A, Pitsch J, Becker A, Anderson AE, Vezzani A, Chetkovich D, Bernard C.

Mol Neurobiol. 2018 Sep;55(9):7500-7511. doi: 10.1007/s12035-018-0915-1. Epub 2018 Feb 9.

8.

miR147b: A novel key regulator of interleukin 1 beta-mediated inflammation in human astrocytes.

van Scheppingen J, Mills JD, Zimmer TS, Broekaart DWM, Iori V, Bongaarts A, Anink JJ, Iyer AM, Korotkov A, Jansen FE, van Hecke W, Spliet WG, van Rijen PC, Baayen JC, Vezzani A, van Vliet EA, Aronica E.

Glia. 2018 May;66(5):1082-1097. doi: 10.1002/glia.23302. Epub 2018 Jan 31.

PMID:
29384235
9.

Structural brain abnormalities in the common epilepsies assessed in a worldwide ENIGMA study.

Whelan CD, Altmann A, Botía JA, Jahanshad N, Hibar DP, Absil J, Alhusaini S, Alvim MKM, Auvinen P, Bartolini E, Bergo FPG, Bernardes T, Blackmon K, Braga B, Caligiuri ME, Calvo A, Carr SJ, Chen J, Chen S, Cherubini A, David P, Domin M, Foley S, França W, Haaker G, Isaev D, Keller SS, Kotikalapudi R, Kowalczyk MA, Kuzniecky R, Langner S, Lenge M, Leyden KM, Liu M, Loi RQ, Martin P, Mascalchi M, Morita ME, Pariente JC, Rodríguez-Cruces R, Rummel C, Saavalainen T, Semmelroch MK, Severino M, Thomas RH, Tondelli M, Tortora D, Vaudano AE, Vivash L, von Podewils F, Wagner J, Weber B, Yao Y, Yasuda CL, Zhang G, Bargalló N, Bender B, Bernasconi N, Bernasconi A, Bernhardt BC, Blümcke I, Carlson C, Cavalleri GL, Cendes F, Concha L, Delanty N, Depondt C, Devinsky O, Doherty CP, Focke NK, Gambardella A, Guerrini R, Hamandi K, Jackson GD, Kälviäinen R, Kochunov P, Kwan P, Labate A, McDonald CR, Meletti S, O'Brien TJ, Ourselin S, Richardson MP, Striano P, Thesen T, Wiest R, Zhang J, Vezzani A, Ryten M, Thompson PM, Sisodiya SM.

Brain. 2018 Feb 1;141(2):391-408. doi: 10.1093/brain/awx341.

10.

Commonalities in epileptogenic processes from different acute brain insults: Do they translate?

Klein P, Dingledine R, Aronica E, Bernard C, Blümcke I, Boison D, Brodie MJ, Brooks-Kayal AR, Engel J Jr, Forcelli PA, Hirsch LJ, Kaminski RM, Klitgaard H, Kobow K, Lowenstein DH, Pearl PL, Pitkänen A, Puhakka N, Rogawski MA, Schmidt D, Sillanpää M, Sloviter RS, Steinhäuser C, Vezzani A, Walker MC, Löscher W.

Epilepsia. 2018 Jan;59(1):37-66. doi: 10.1111/epi.13965. Epub 2017 Dec 15. Review.

11.

Inhibition of monoacylglycerol lipase terminates diazepam-resistant status epilepticus in mice and its effects are potentiated by a ketogenic diet.

Terrone G, Pauletti A, Salamone A, Rizzi M, Villa BR, Porcu L, Sheehan MJ, Guilmette E, Butler CR, Piro JR, Samad TA, Vezzani A.

Epilepsia. 2018 Jan;59(1):79-91. doi: 10.1111/epi.13950. Epub 2017 Nov 24.

12.

High Mobility Group Box 1 is a novel pathogenic factor and a mechanistic biomarker for epilepsy.

Ravizza T, Terrone G, Salamone A, Frigerio F, Balosso S, Antoine DJ, Vezzani A.

Brain Behav Immun. 2018 Aug;72:14-21. doi: 10.1016/j.bbi.2017.10.008. Epub 2017 Oct 13.

PMID:
29031614
13.

Inflammation and Epilepsy: Preclinical Findings and Potential Clinical Translation.

Terrone G, Salamone A, Vezzani A.

Curr Pharm Des. 2017;23(37):5569-5576. doi: 10.2174/1381612823666170926113754.

PMID:
28950818
14.

Inhibition of IL-1β Signaling Normalizes NMDA-Dependent Neurotransmission and Reduces Seizure Susceptibility in a Mouse Model of Creutzfeldt-Jakob Disease.

Bertani I, Iori V, Trusel M, Maroso M, Foray C, Mantovani S, Tonini R, Vezzani A, Chiesa R.

J Neurosci. 2017 Oct 25;37(43):10278-10289. doi: 10.1523/JNEUROSCI.1301-17.2017. Epub 2017 Sep 18.

15.

Neuroinflammatory targets and treatments for epilepsy validated in experimental models.

Aronica E, Bauer S, Bozzi Y, Caleo M, Dingledine R, Gorter JA, Henshall DC, Kaufer D, Koh S, Löscher W, Louboutin JP, Mishto M, Norwood BA, Palma E, Poulter MO, Terrone G, Vezzani A, Kaminski RM.

Epilepsia. 2017 Jul;58 Suppl 3:27-38. doi: 10.1111/epi.13783. Review.

16.

Introduction to the 2nd Meeting on Immunity and Inflammation in Epilepsy (IIE2016).

Vezzani A, Rüegg S.

Epilepsia. 2017 Jul;58 Suppl 3:7-10. doi: 10.1111/epi.13780.

17.

Development of In Vivo Imaging Tools for Investigating Astrocyte Activation in Epileptogenesis.

Kostoula C, Pascente R, Ravizza T, McCown T, Schoch S, Vezzani A, Becker AJ, van Loo KMJ.

Mol Neurobiol. 2018 May;55(5):4463-4472. doi: 10.1007/s12035-017-0660-x. Epub 2017 Jul 1.

PMID:
28669125
18.

Epigenetic control of epileptogenesis by miR-146a.

Iori V, Aronica E, Vezzani A.

Oncotarget. 2017 Jul 11;8(28):45040-45041. doi: 10.18632/oncotarget.18364. No abstract available.

19.

Targeting oxidative stress improves disease outcomes in a rat model of acquired epilepsy.

Pauletti A, Terrone G, Shekh-Ahmad T, Salamone A, Ravizza T, Rizzi M, Pastore A, Pascente R, Liang LP, Villa BR, Balosso S, Abramov AY, van Vliet EA, Del Giudice E, Aronica E, Antoine DJ, Patel M, Walker MC, Vezzani A.

Brain. 2017 Jul 1;140(7):1885-1899. doi: 10.1093/brain/awx117.

20.

Molecular isoforms of high-mobility group box 1 are mechanistic biomarkers for epilepsy.

Walker LE, Frigerio F, Ravizza T, Ricci E, Tse K, Jenkins RE, Sills GJ, Jorgensen A, Porcu L, Thippeswamy T, Alapirtti T, Peltola J, Brodie MJ, Park BK, Marson AG, Antoine DJ, Vezzani A, Pirmohamed M.

J Clin Invest. 2017 Jun 1;127(6):2118-2132. doi: 10.1172/JCI92001. Epub 2017 May 15.

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