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See 1 citation in Urology 2005:

Urology. 2005 Sep;66(3):597-601.

Relationship between serum sex steroids and Aging Male Symptoms score and International Index of Erectile Function.

Author information

1
Department of Urology, University of Kirikkale, Kirikkale, Turkey. mmbasar@hotmail.com

Abstract

OBJECTIVES:

To determine the relationship between the total and subscale scores of the Aging Male Symptoms (AMS) and International Index of Erectile Function (IIEF) questionnaires, age, and serum sex steroids levels.

METHODS:

A total of 348 patients enrolled in the study answered the AMS and IIEF questionnaires. Hormonal analysis, including total testosterone, free testosterone (FT), estradiol (E2), and dehydroepiandrosterone-sulphate (DHEA-S) measurement, were performed. The patients with a total AMS score of 29 were considered to have aging male symptoms and the patients with an IIEF score of less than 26 were considered to have sexual dysfunction.

RESULTS:

Although DHEA-S levels were significantly lower and E2 levels were greater in the men with aging male symptoms according to the AMS, the DHEA-S and FT levels were significantly lower in the men with sexual dysfunction, as determined by the IIEF score. Serum DHEA-S and FT levels and age correlated significantly with the IIEF scores. The total AMS score correlated significantly only with age. Although serum total testosterone, FT, and DHEA-S levels correlated significantly with the andrologic symptoms of AMS, the serum E2 levels correlated with psychological symptoms of AMS.

CONCLUSIONS:

Although aging male symptoms and the effects of hormonal changes on these symptoms have been controversial, DHEA-S and E2 might play some important roles in the symptoms of aging men.

PMID:
16140085
DOI:
10.1016/j.urology.2005.03.060
[Indexed for MEDLINE]

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