Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2009 1
2011 2
2012 2
2013 2
2014 1
2015 1
2017 1
2018 3
2019 4
2020 3
2021 8
2022 3
2023 1
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

29 results

Results by year

Filters applied: . Clear all
Page 1
UBAC2 promotes bladder cancer proliferation through BCRC-3/miRNA-182-5p/p27 axis.
Gu C, Zhao K, Zhou N, Liu F, Xie F, Yu S, Feng Y, Chen L, Yang J, Tian F, Jiang G. Gu C, et al. Cell Death Dis. 2020 Sep 10;11(9):733. doi: 10.1038/s41419-020-02935-7. Cell Death Dis. 2020. PMID: 32913183 Free PMC article.
However, the functions and underlying molecular mechanisms of UBAC2 in bladder cancer (BC) development have not been defined. In this study, we found that both UBAC2 mRNA and protein levels were upregulated in BC tissues and cell lines, and knockdown of UBAC2 …
However, the functions and underlying molecular mechanisms of UBAC2 in bladder cancer (BC) development have not been defined. In this …
Association between UBAC2 gene polymorphism and the risk of noise-induced hearing loss: a cross-sectional study.
Wan L, Zhang L, Sun P, Han L, Zhang H, Zhu B, Wang B. Wan L, et al. Environ Sci Pollut Res Int. 2022 May;29(22):32947-32958. doi: 10.1007/s11356-021-18360-y. Epub 2022 Jan 12. Environ Sci Pollut Res Int. 2022. PMID: 35020141

The results of the luciferase reporter assays showed that the fluorescence intensity of CTCF-OE + UBAC2 WT + TK was significantly higher than that of CTCF-NC + UBAC2 WT + TK and CTCF-OE + UBAC2 MT + TK (all P < 0.01). ...UBAC2 gene polymorphism is r

…
The results of the luciferase reporter assays showed that the fluorescence intensity of CTCF-OE + UBAC2 WT + TK was significantly hig …
HYPK coordinates degradation of polyneddylated proteins by autophagy.
Ghosh DK, Ranjan A. Ghosh DK, et al. Autophagy. 2022 Aug;18(8):1763-1784. doi: 10.1080/15548627.2021.1997053. Epub 2021 Nov 26. Autophagy. 2022. PMID: 34836490 Free PMC article.
Thus, we propose an indispensable and additive role of neddylation and HYPK in clearance of protein aggregates by autophagy, resulting in cytoprotective effect during proteotoxic stress.Abbreviations: ATG5, autophagy related 5; ATG12, autophagy related 12; ATG14, autophagy relate …
Thus, we propose an indispensable and additive role of neddylation and HYPK in clearance of protein aggregates by autophagy, resulting in cy …
Arabidopsis Endoplasmic Reticulum-Localized UBAC2 Proteins Interact with PAMP-INDUCED COILED-COIL to Regulate Pathogen-Induced Callose Deposition and Plant Immunity.
Wang Z, Li X, Wang X, Liu N, Xu B, Peng Q, Guo Z, Fan B, Zhu C, Chen Z. Wang Z, et al. Plant Cell. 2019 Jan;31(1):153-171. doi: 10.1105/tpc.18.00334. Epub 2019 Jan 3. Plant Cell. 2019. PMID: 30606781 Free PMC article.
The ubac2 mutants showed normal PRR biogenesis, MAPK activation, ROS burst, and PTI-associated gene expression. Pathogen- and PAMP-induced callose deposition, however, was compromised in ubac2 mutants. UBAC2 proteins interact with the plant-specific long coil …
The ubac2 mutants showed normal PRR biogenesis, MAPK activation, ROS burst, and PTI-associated gene expression. Pathogen- and PAMP-in …
Comprehensive analysis of the association between UBAC2 polymorphisms and Behcet's disease in a Japanese population.
Yamazoe K, Meguro A, Takeuchi M, Shibuya E, Ohno S, Mizuki N. Yamazoe K, et al. Sci Rep. 2017 Apr 7;7(1):742. doi: 10.1038/s41598-017-00877-3. Sci Rep. 2017. PMID: 28389674 Free PMC article.
Behcet's disease (BD) is reportedly associated with polymorphisms of the ubiquitin-associated domain containing 2 (UBAC2) gene in Turkish, Italian, and Chinese populations. Here we investigated whether UBAC2 polymorphisms were associated with BD in a Japanese popula …
Behcet's disease (BD) is reportedly associated with polymorphisms of the ubiquitin-associated domain containing 2 (UBAC2) gene in Tur …
A putative functional variant within the UBAC2 gene is associated with increased risk of Behcet's disease.
Sawalha AH, Hughes T, Nadig A, Yılmaz V, Aksu K, Keser G, Cefle A, Yazıcı A, Ergen A, Alarcón-Riquelme ME, Salvarani C, Casali B, Direskeneli H, Saruhan-Direskeneli G. Sawalha AH, et al. Arthritis Rheum. 2011 Nov;63(11):3607-12. doi: 10.1002/art.30604. Arthritis Rheum. 2011. PMID: 21918955 Free PMC article.
Genotyping of 14 single-nucleotide polymorphisms (SNPs) within and around UBAC2 was performed using TaqMan SNP genotyping assays. RESULTS: The genetic association between Behcet's disease and UBAC2 was established, replicated, and confirmed (meta-analysis odds ratio …
Genotyping of 14 single-nucleotide polymorphisms (SNPs) within and around UBAC2 was performed using TaqMan SNP genotyping assays. RES …
PS-341 alleviates chronic low-grade inflammation and improves insulin sensitivity through the inhibition of TM4 (UBAC2) degradation.
Chen L, Ye K, Feng X, Li L, Li Q, Huang Y, Wang X, Li R, Hu C, Yang Z, Lu B, Yang Y, Wen J, Zhang Z, He M, Wang Q, Zhou W, Li Y, Liu N, Huang J, Shen Q, Yao Q, Hu R. Chen L, et al. Nutr Metab (Lond). 2021 Jun 1;18(1):54. doi: 10.1186/s12986-021-00579-8. Nutr Metab (Lond). 2021. PMID: 34074311 Free PMC article.
BACKGROUND: The TM4 (UBAC2) protein, which contains 4 transmembrane domains and one ubiquitin binding domain, is mainly expressed in cell and nuclear membranes. ...
BACKGROUND: The TM4 (UBAC2) protein, which contains 4 transmembrane domains and one ubiquitin binding domain, is mainly expressed in …
The oxysterol receptor GPR183 in inflammatory bowel diseases.
Misselwitz B, Wyss A, Raselli T, Cerovic V, Sailer AW, Krupka N, Ruiz F, Pot C, Pabst O. Misselwitz B, et al. Br J Pharmacol. 2021 Aug;178(16):3140-3156. doi: 10.1111/bph.15311. Epub 2021 Jan 12. Br J Pharmacol. 2021. PMID: 33145756 Free article. Review.
GPR183 has been mapped to an IBD risk locus, however another gene, Ubac2 is encoded on the reverse strand and associated with Behcet's disease, therefore the role of GPR183 as a genetic risk factor requires validation. ...
GPR183 has been mapped to an IBD risk locus, however another gene, Ubac2 is encoded on the reverse strand and associated with Behcet' …
Replication study confirms the association between UBAC2 and Behcet's disease in two independent Chinese sets of patients and controls.
Hou S, Shu Q, Jiang Z, Chen Y, Li F, Chen F, Kijlstra A, Yang P. Hou S, et al. Arthritis Res Ther. 2012 Mar 29;14(2):R70. doi: 10.1186/ar3789. Arthritis Res Ther. 2012. PMID: 22455605 Free PMC article.
The mRNA expression of UBAC2 transcript variant 2 was significantly increased in skin of BD patients as compared with controls (P = 0.004). CONCLUSIONS: This study replicates a predisposition gene to BD, UBAC2, and suggests that UBAC2 may be involved in the d …
The mRNA expression of UBAC2 transcript variant 2 was significantly increased in skin of BD patients as compared with controls (P = 0 …
Dicot-specific ATG8-interacting ATI3 proteins interact with conserved UBAC2 proteins and play critical roles in plant stress responses.
Zhou J, Wang Z, Wang X, Li X, Zhang Z, Fan B, Zhu C, Chen Z. Zhou J, et al. Autophagy. 2018;14(3):487-504. doi: 10.1080/15548627.2017.1422856. Epub 2018 Feb 21. Autophagy. 2018. PMID: 29313416 Free PMC article.
The ati3 and ubac2 mutants are significantly compromised in sensitivity to tunicamycin, an ER stress-inducing agent, but are fully competent in autophagy-dependent ER degradation under conditions of ER stress when using an ER lumenal marker for detection. We propose that A …
The ati3 and ubac2 mutants are significantly compromised in sensitivity to tunicamycin, an ER stress-inducing agent, but are fully co …
29 results