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Discovery of Novel Small Molecule Inhibitors of LIM Domain Kinase for Inhibiting HIV-1.

Yi F, Guo J, Dabbagh D, Spear M, He S, Kehn-Hall K, Fontenot J, Yin Y, Bibian M, Park CM, Zheng K, Park H, Soloveva V, Gharaibeh D, Retterer C, Zamani R, Pitt ML, Naughton J, Jiang Y, Shang H, Hakami RM, Ling B, Young JA, Bavari S, Xu X, Feng Y, Wu Y.

J Virol. 2017 Apr 5. pii: JVI.02418-16. doi: 10.1128/JVI.02418-16. [Epub ahead of print]


Infection of rhesus macaques with a pool of simian immunodeficiency virus with the envelope genes from acute HIV-1 infections.

Krebs KC, Tian M, Asmal M, Ling B, Nelson K, Henry K, Gibson R, Li Y, Han W, Shattock RJ, Veazey RS, Letvin N, Arts EJ, Gao Y.

AIDS Res Ther. 2016 Nov 25;13(1):41.


Effects of treatment with suppressive combination antiretroviral drug therapy and the histone deacetylase inhibitor suberoylanilide hydroxamic acid; (SAHA) on SIV-infected Chinese rhesus macaques.

Ling B, Piatak M Jr, Rogers L, Johnson AM, Russell-Lodrigue K, Hazuda DJ, Lifson JD, Veazey RS.

PLoS One. 2014 Jul 17;9(7):e102795. doi: 10.1371/journal.pone.0102795. eCollection 2014.


Genistein interferes with SDF-1- and HIV-mediated actin dynamics and inhibits HIV infection of resting CD4 T cells.

Guo J, Xu X, Rasheed TK, Yoder A, Yu D, Liang H, Yi F, Hawley T, Jin T, Ling B, Wu Y.

Retrovirology. 2013 Jun 19;10:62. doi: 10.1186/1742-4690-10-62.


Effect of combination antiretroviral therapy on Chinese rhesus macaques of simian immunodeficiency virus infection.

Ling B, Rogers L, Johnson AM, Piatak M, Lifson J, Veazey RS.

AIDS Res Hum Retroviruses. 2013 Nov;29(11):1465-74. doi: 10.1089/AID.2012.0378. Epub 2013 Mar 8.


The large intestine as a major reservoir for simian immunodeficiency virus in macaques with long-term, nonprogressing infection.

Ling B, Mohan M, Lackner AA, Green LC, Marx PA, Doyle LA, Veazey RS.

J Infect Dis. 2010 Dec 15;202(12):1846-54. doi: 10.1086/657413. Epub 2010 Nov 4.


The most common Chinese rhesus macaque MHC class I molecule shares peptide binding repertoire with the HLA-B7 supertype.

Solomon C, Southwood S, Hoof I, Rudersdorf R, Peters B, Sidney J, Pinilla C, Marcondes MC, Ling B, Marx P, Sette A, Mothé BR.

Immunogenetics. 2010 Jul;62(7):451-64. doi: 10.1007/s00251-010-0450-3. Epub 2010 May 18.


The level of monocyte turnover predicts disease progression in the macaque model of AIDS.

Hasegawa A, Liu H, Ling B, Borda JT, Alvarez X, Sugimoto C, Vinet-Oliphant H, Kim WK, Williams KC, Ribeiro RM, Lackner AA, Veazey RS, Kuroda MJ.

Blood. 2009 Oct 1;114(14):2917-25. doi: 10.1182/blood-2009-02-204263. Epub 2009 Apr 21.


Topically applied recombinant chemokine analogues fully protect macaques from vaginal simian-human immunodeficiency virus challenge.

Veazey RS, Ling B, Green LC, Ribka EP, Lifson JD, Piatak M Jr, Lederman MM, Mosier D, Offord R, Hartley O.

J Infect Dis. 2009 May 15;199(10):1525-7. doi: 10.1086/598685.


Control of viremia and maintenance of intestinal CD4(+) memory T cells in SHIV(162P3) infected macaques after pathogenic SIV(MAC251) challenge.

Pahar B, Lackner AA, Piatak M Jr, Lifson JD, Wang X, Das A, Ling B, Montefiori DC, Veazey RS.

Virology. 2009 May 10;387(2):273-84. doi: 10.1016/j.virol.2009.02.014. Epub 2009 Mar 18.


Copy number variation of CCL3-like genes affects rate of progression to simian-AIDS in Rhesus Macaques (Macaca mulatta).

Degenhardt JD, de Candia P, Chabot A, Schwartz S, Henderson L, Ling B, Hunter M, Jiang Z, Palermo RE, Katze M, Eichler EE, Ventura M, Rogers J, Marx P, Gilad Y, Bustamante CD.

PLoS Genet. 2009 Jan;5(1):e1000346. doi: 10.1371/journal.pgen.1000346. Epub 2009 Jan 23.


Differential CD4+ T-lymphocyte apoptosis and bystander T-cell activation in rhesus macaques and sooty mangabeys during acute simian immunodeficiency virus infection.

Meythaler M, Martinot A, Wang Z, Pryputniewicz S, Kasheta M, Ling B, Marx PA, O'Neil S, Kaur A.

J Virol. 2009 Jan;83(2):572-83. doi: 10.1128/JVI.01715-08. Epub 2008 Nov 5.


Nonpathogenic CCR2-tropic SIVrcm after serial passage and its effect on SIVmac infection of Indian rhesus macaques.

Ling B, Veazey RS, Marx PA.

Virology. 2008 Sep 15;379(1):38-44. doi: 10.1016/j.virol.2008.06.012. Epub 2008 Jul 26.


Early restoration of mucosal CD4 memory CCR5 T cells in the gut of SIV-infected rhesus predicts long term non-progression.

Ling B, Veazey RS, Hart M, Lackner AA, Kuroda M, Pahar B, Marx PA.

AIDS. 2007 Nov 30;21(18):2377-85.


Detection and partial characterization of simian immunodeficiency virus SIVsm strains from bush meat samples from rural Sierra Leone.

Apetrei C, Metzger MJ, Richardson D, Ling B, Telfer PT, Reed P, Robertson DL, Marx PA.

J Virol. 2005 Feb;79(4):2631-6.


A link between SIVsm in sooty mangabeys (SM) in wild-living monkeys in Sierra Leone and SIVsm in an American-based SM colony.

Ling B, Telfer P, Reed P, Robertson DL, Marx PA.

AIDS Res Hum Retroviruses. 2004 Dec;20(12):1348-51.


Classic AIDS in a sooty mangabey after an 18-year natural infection.

Ling B, Apetrei C, Pandrea I, Veazey RS, Lackner AA, Gormus B, Marx PA.

J Virol. 2004 Aug;78(16):8902-8.


Decreased CCR5 expression on CD4+ T cells of SIV-infected sooty mangabeys.

Veazey R, Ling B, Pandrea I, McClure H, Lackner A, Marx P.

AIDS Res Hum Retroviruses. 2003 Mar;19(3):227-33.


Boosting of SIV-specific T cell responses in rhesus macaques that resist repeated intravaginal challenge with SIVmac251.

Shacklett BL, Ling B, Veazey RS, Luckay A, Moretto WJ, Wilkens DT, Hu J, Israel ZR, Nixon DF, Marx PA.

AIDS Res Hum Retroviruses. 2002 Sep 20;18(14):1081-8.


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