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Items: 1 to 20 of 1373

1.

Subacute combined degeneration of the spinal cord is associated with tripterygium glycoside tablet usage.

Zhuang W, Sun N, Chan C, Huang L, Gao L, Song J, Lin X.

Neurol Sci. 2019 Mar 21. doi: 10.1007/s10072-019-03845-z. [Epub ahead of print]

PMID:
30903417
2.

Friedelane-type triterpene cyclase in celastrol biosynthesis from Tripterygium wilfordii and its application for triterpenes biosynthesis in yeast.

Zhou J, Hu T, Gao L, Su P, Zhang Y, Zhao Y, Chen S, Tu L, Song Y, Wang X, Huang L, Gao W.

New Phytol. 2019 Mar 21. doi: 10.1111/nph.15809. [Epub ahead of print]

PMID:
30895623
3.

Celastrol Reduces Obesity in MC4R Deficiency and Stimulates Sympathetic Nerve Activity Affecting Metabolic and Cardiovascular Functions.

Saito K, Davis KC, Morgan DA, Toth BA, Jiang J, Singh U, Berglund ED, Grobe JL, Rahmouni K, Cui H.

Diabetes. 2019 Mar 20. pii: db181167. doi: 10.2337/db18-1167. [Epub ahead of print]

PMID:
30894367
4.

The plant triterpenoid celastrol blocks PINK1-dependent mitophagy by disrupting PINK1's association with the mitochondrial protein TOM20.

Zhang C, Wang R, Liu Z, Bunker E, Lee S, Giuntini M, Chapnick D, Liu X.

J Biol Chem. 2019 Mar 18. pii: jbc.RA118.006506. doi: 10.1074/jbc.RA118.006506. [Epub ahead of print]

5.
6.

Simultaneous determination of seven effective components of Tripterygium glycosides in human biological matrices by ultra performance liquid chromatography-triple quadrupole mass spectrometry.

Du X, He X, Huang Y, Fu B, Liang B, Lv C, Li Y, Gao X, Wang Y.

J Chromatogr B Analyt Technol Biomed Life Sci. 2019 Feb 25;1113:1-13. doi: 10.1016/j.jchromb.2019.02.024. [Epub ahead of print]

PMID:
30877981
7.

Triptolide ameliorates lupus via the induction of miR-125a-5p mediating Treg upregulation.

Zhao X, Tang X, Yan Q, Song H, Li Z, Wang D, Chen H, Sun L.

Int Immunopharmacol. 2019 Mar 9;71:14-21. doi: 10.1016/j.intimp.2019.02.047. [Epub ahead of print]

PMID:
30861393
8.

Tripterygium glycoside fraction n2: Alleviation of DSS-induced colitis by modulating immune homeostasis in mice.

Yang YQ, Wu YF, Xu FF, Deng JB, Wu LL, Han XD, Liang J, Guo DA, Liu B.

Phytomedicine. 2019 Jan 30;58:152855. doi: 10.1016/j.phymed.2019.152855. [Epub ahead of print]

PMID:
30851581
9.

MicroRNA expression, targeting, release dynamics and early-warning biomarkers in acute cardiotoxicity induced by triptolide in rats.

Wang SR, Chen X, Ling S, Ni RZ, Guo H, Xu JW.

Biomed Pharmacother. 2019 Mar;111:1467-1477. doi: 10.1016/j.biopha.2018.12.109. Epub 2019 Jan 31.

10.

Tripterygium glycoside protects diabetic kidney disease mouse serum-induced podocyte injury by upregulating autophagy and downregulating β-arrestin-1.

Zhan H, Jin J, Liang S, Zhao L, Gong J, He Q.

Histol Histopathol. 2019 Mar 6:18097. doi: 10.14670/HH-18-097. [Epub ahead of print]

PMID:
30839094
11.

The study of cellular mechanism of triptolide in the treatment of cancer, bone loss and cardiovascular disease and triptolide's toxicity.

Wang Y, Wang B, Yang X.

Curr Stem Cell Res Ther. 2019 Mar 1. doi: 10.2174/1574888X14666190301155810. [Epub ahead of print]

PMID:
30834841
12.

Reproductive Systemic Toxicity and Mechanism of Glucosides of Tripterygium wilfordii Hook. F. (GTW).

Guo J, Huang Y, Lei X, Zhang H, Xiao B, Han Z, Liang C, Yang W.

Ann Clin Lab Sci. 2019 Jan;49(1):36-49.

PMID:
30814076
13.

Rapid identification of triptolide in Tripterygium wilfordii products by gold immunochromatographic assay.

Duan Y, Luo J, Liu C, Shan L, Dou X, Yang S, Yang M.

J Pharm Biomed Anal. 2019 May 10;168:102-112. doi: 10.1016/j.jpba.2019.02.020. Epub 2019 Feb 14.

PMID:
30802749
14.

Tripterine up-regulates miR-223 to alleviate lipopolysaccharide-induced damage in murine chondrogenic ATDC5 cells.

Li X, Wei W, Zhao Z, Lv S.

Int J Immunopathol Pharmacol. 2019 Jan-Dec;33:2058738418824521. doi: 10.1177/2058738418824521.

15.

Celastrol suppresses nitric oxide synthases and the angiogenesis pathway in colorectal cancer.

Gao Y, Zhou S, Pang L, Yang J, Li HJ, Huo X, Qian SY.

Free Radic Res. 2019 Feb 18:1-11. doi: 10.1080/10715762.2019.1575512. [Epub ahead of print]

PMID:
30773944
16.

Celastrol attenuates renal injury in diabetic rats via MAPK/NF-κB pathway.

Zhang M, Chen Y, Yang MJ, Fan XR, Xie H, Zhang L, Nie YS, Yan M.

Phytother Res. 2019 Feb 15. doi: 10.1002/ptr.6314. [Epub ahead of print]

PMID:
30768745
17.

Treatment with celastrol protects against obesity through suppression of galanin-induced fat intake and activation of PGC-1α/GLUT4 axis-mediated glucose consumption.

Fang P, He B, Yu M, Shi M, Zhu Y, Zhang Z, Bo P.

Biochim Biophys Acta Mol Basis Dis. 2019 Feb 10. pii: S0925-4439(19)30045-6. doi: 10.1016/j.bbadis.2019.02.002. [Epub ahead of print]

PMID:
30742994
18.

Demethylzeylasteral (T-96) inhibits triple-negative breast cancer invasion by blocking the canonical and non-canonical TGF-β signaling pathways.

Li L, Ji Y, Fan J, Li F, Li Y, Wu M, Cheng H, Xu C.

Naunyn Schmiedebergs Arch Pharmacol. 2019 Feb 6. doi: 10.1007/s00210-019-01614-5. [Epub ahead of print]

PMID:
30729271
19.

Modulation of Lipid Metabolism by Celastrol.

Zhang T, Zhao Q, Xiao X, Yang R, Hu D, Zhu X, Gonzalez FJ, Li F.

J Proteome Res. 2019 Mar 1;18(3):1133-1144. doi: 10.1021/acs.jproteome.8b00797. Epub 2019 Feb 12.

PMID:
30706713
20.

New Terpenoids And Lignans From The Twigs Of Tripterygium Hypoglaucum.

Zheng H, Wang L, Yang T, Liu D, Li HM, Chen XQ, Li RT.

Nat Prod Res. 2019 Jan 29:1-9. doi: 10.1080/14786419.2018.1564297. [Epub ahead of print]

PMID:
30691300

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