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Items: 1 to 20 of 40

1.

Small-Angle X-Ray Scattering for the Study of Proteins in the Ubiquitin Pathway.

Trempe JF, Gehring K.

Methods Mol Biol. 2018;1844:197-208. doi: 10.1007/978-1-4939-8706-1_13.

PMID:
30242711
2.

New insights into the structure of PINK1 and the mechanism of ubiquitin phosphorylation.

Rasool S, Trempe JF.

Crit Rev Biochem Mol Biol. 2018 Oct;53(5):515-534. doi: 10.1080/10409238.2018.1491525. Epub 2018 Sep 21.

PMID:
30238821
3.

Publisher Correction: Mechanism of parkin activation by phosphorylation.

Sauvé V, Sung G, Soya N, Kozlov G, Blaimschein N, Miotto LS, Trempe JF, Lukacs GL, Gehring K.

Nat Struct Mol Biol. 2018 Aug;25(8):744. doi: 10.1038/s41594-018-0105-x.

PMID:
30026521
4.

Mechanism of parkin activation by phosphorylation.

Sauvé V, Sung G, Soya N, Kozlov G, Blaimschein N, Miotto LS, Trempe JF, Lukacs GL, Gehring K.

Nat Struct Mol Biol. 2018 Jul;25(7):623-630. doi: 10.1038/s41594-018-0088-7. Epub 2018 Jul 2. Erratum in: Nat Struct Mol Biol. 2018 Aug;25(8):744.

PMID:
29967542
5.

Structures of ubiquitin-like (Ubl) and Hsp90-like domains of sacsin provide insight into pathological mutations.

Ménade M, Kozlov G, Trempe JF, Pande H, Shenker S, Wickremasinghe S, Li X, Hojjat H, Dicaire MJ, Brais B, McPherson PS, Wong MJH, Young JC, Gehring K.

J Biol Chem. 2018 Aug 17;293(33):12832-12842. doi: 10.1074/jbc.RA118.003939. Epub 2018 Jun 26.

PMID:
29945973
6.

The GBA p.Trp378Gly mutation is a probable French-Canadian founder mutation causing Gaucher disease and synucleinopathies.

Ruskey JA, Zhou S, Santiago R, Franche LA, Alam A, Roncière L, Spiegelman D, Fon EA, Trempe JF, Kalia LV, Postuma RB, Dupre N, Rivard GE, Assouline S, Amato D, Gan-Or Z.

Clin Genet. 2018 Oct;94(3-4):339-345. doi: 10.1111/cge.13405. Epub 2018 Jul 16.

PMID:
29920646
7.

Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy.

McLelland GL, Goiran T, Yi W, Dorval G, Chen CX, Lauinger ND, Krahn AI, Valimehr S, Rakovic A, Rouiller I, Durcan TM, Trempe JF, Fon EA.

Elife. 2018 Apr 20;7. pii: e32866. doi: 10.7554/eLife.32866.

8.

PINK1 autophosphorylation is required for ubiquitin recognition.

Rasool S, Soya N, Truong L, Croteau N, Lukacs GL, Trempe JF.

EMBO Rep. 2018 Apr;19(4). pii: e44981. doi: 10.15252/embr.201744981. Epub 2018 Feb 23.

PMID:
29475881
9.

Structure-guided mutagenesis reveals a hierarchical mechanism of Parkin activation.

Tang MY, Vranas M, Krahn AI, Pundlik S, Trempe JF, Fon EA.

Nat Commun. 2017 Mar 9;8:14697. doi: 10.1038/ncomms14697.

10.

Structural studies of the yeast DNA damage-inducible protein Ddi1 reveal domain architecture of this eukaryotic protein family.

Trempe JF, Šašková KG, Sivá M, Ratcliffe CD, Veverka V, Hoegl A, Ménade M, Feng X, Shenker S, Svoboda M, Kožíšek M, Konvalinka J, Gehring K.

Sci Rep. 2016 Sep 20;6:33671. doi: 10.1038/srep33671.

11.

Human DNA-Damage-Inducible 2 Protein Is Structurally and Functionally Distinct from Its Yeast Ortholog.

Sivá M, Svoboda M, Veverka V, Trempe JF, Hofmann K, Kožíšek M, Hexnerová R, Sedlák F, Belza J, Brynda J, Šácha P, Hubálek M, Starková J, Flaisigová I, Konvalinka J, Šašková KG.

Sci Rep. 2016 Jul 27;6:30443. doi: 10.1038/srep30443.

12.

A Ubl/ubiquitin switch in the activation of Parkin.

Sauvé V, Lilov A, Seirafi M, Vranas M, Rasool S, Kozlov G, Sprules T, Wang J, Trempe JF, Gehring K.

EMBO J. 2015 Oct 14;34(20):2492-505. doi: 10.15252/embj.201592237. Epub 2015 Aug 7.

13.

The E3 ubiquitin ligase parkin is recruited to the 26 S proteasome via the proteasomal ubiquitin receptor Rpn13.

Aguileta MA, Korac J, Durcan TM, Trempe JF, Haber M, Gehring K, Elsasser S, Waidmann O, Fon EA, Husnjak K.

J Biol Chem. 2015 Mar 20;290(12):7492-505. doi: 10.1074/jbc.M114.614925. Epub 2015 Feb 9.

14.

Ubiquitin is phosphorylated by PINK1 to activate parkin.

Koyano F, Okatsu K, Kosako H, Tamura Y, Go E, Kimura M, Kimura Y, Tsuchiya H, Yoshihara H, Hirokawa T, Endo T, Fon EA, Trempe JF, Saeki Y, Tanaka K, Matsuda N.

Nature. 2014 Jun 5;510(7503):162-6. doi: 10.1038/nature13392. Epub 2014 Jun 4.

PMID:
24784582
15.

Family of phenylacetyl-CoA monooxygenases differs in subunit organization from other monooxygenases.

Grishin AM, Ajamian E, Tao L, Bostina M, Zhang L, Trempe JF, Menard R, Rouiller I, Cygler M.

J Struct Biol. 2013 Nov;184(2):147-54. doi: 10.1016/j.jsb.2013.09.012. Epub 2013 Sep 20.

PMID:
24055609
16.

Structure of parkin reveals mechanisms for ubiquitin ligase activation.

Trempe JF, Sauvé V, Grenier K, Seirafi M, Tang MY, Ménade M, Al-Abdul-Wahid S, Krett J, Wong K, Kozlov G, Nagar B, Fon EA, Gehring K.

Science. 2013 Jun 21;340(6139):1451-5. doi: 10.1126/science.1237908. Epub 2013 May 9.

17.

Structure and Function of Parkin, PINK1, and DJ-1, the Three Musketeers of Neuroprotection.

Trempe JF, Fon EA.

Front Neurol. 2013 Apr 19;4:38. doi: 10.3389/fneur.2013.00038. eCollection 2013.

18.

Reading the ubiquitin postal code.

Trempe JF.

Curr Opin Struct Biol. 2011 Dec;21(6):792-801. doi: 10.1016/j.sbi.2011.09.009. Epub 2011 Oct 27. Review.

PMID:
22036065
19.

Self-association studies of the bifunctional N-acetylglucosamine-1-phosphate uridyltransferase from Escherichia coli.

Trempe JF, Shenker S, Kozlov G, Gehring K.

Protein Sci. 2011 Apr;20(4):745-52. doi: 10.1002/pro.608. Epub 2011 Mar 11.

20.

A new crystal form of Lys48-linked diubiquitin.

Trempe JF, Brown NR, Noble ME, Endicott JA.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Sep 1;66(Pt 9):994-8. doi: 10.1107/S1744309110027600. Epub 2010 Aug 21.

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