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Items: 1 to 20 of 259


Optimal contrast-enhanced MRI image thresholding for accurate prediction of ventricular tachycardia using ex-vivo high resolution models.

Deng D, Nikolov P, Arevalo HJ, Trayanova NA.

Comput Biol Med. 2018 Oct 3. pii: S0010-4825(18)30293-2. doi: 10.1016/j.compbiomed.2018.09.031. [Epub ahead of print]


The Fibrotic Substrate in Persistent Atrial Fibrillation Patients: Comparison Between Predictions From Computational Modeling and Measurements From Focal Impulse and Rotor Mapping.

Boyle PM, Hakim JB, Zahid S, Franceschi WH, Murphy MJ, Prakosa A, Aronis KN, Zghaib T, Balouch M, Ipek EG, Chrispin J, Berger RD, Ashikaga H, Marine JE, Calkins H, Nazarian S, Spragg DD, Trayanova NA.

Front Physiol. 2018 Aug 29;9:1151. doi: 10.3389/fphys.2018.01151. eCollection 2018.


Tropomyosin dynamics during cardiac muscle contraction as governed by a multi-well energy landscape.

Aboelkassem Y, Trayanova N.

Prog Biophys Mol Biol. 2018 Aug 22. pii: S0079-6107(18)30086-5. doi: 10.1016/j.pbiomolbio.2018.07.015. [Epub ahead of print]


Increased Thin Filament Activation Enhances Alternans in Human Chronic Atrial Fibrillation.

Zile MA, Trayanova NA.

Am J Physiol Heart Circ Physiol. 2018 Aug 24. doi: 10.1152/ajpheart.00658.2017. [Epub ahead of print]


Role of 3-Dimensional Architecture of Scar and Surviving Tissue in Ventricular Tachycardia: Insights From High-Resolution Ex Vivo Porcine Models.

Pashakhanloo F, Herzka DA, Halperin H, McVeigh ER, Trayanova NA.

Circ Arrhythm Electrophysiol. 2018 Jun;11(6):e006131. doi: 10.1161/CIRCEP.117.006131.


Field of view of mapping catheters quantified by electrogram associations with radius of myocardial attenuation on contrast-enhanced cardiac computed tomography.

Misra S, Zahid S, Prakosa A, Saju N, Tandri H, Berger RD, Marine JE, Calkins H, Zipunnikov V, Trayanova N, Zimmerman SL, Nazarian S.

Heart Rhythm. 2018 Jun 2. pii: S1547-5271(18)30564-2. doi: 10.1016/j.hrthm.2018.05.031. [Epub ahead of print]


Quantifying the uncertainty in model parameters using Gaussian process-based Markov chain Monte Carlo in cardiac electrophysiology.

Dhamala J, Arevalo HJ, Sapp J, Horácek BM, Wu KC, Trayanova NA, Wang L.

Med Image Anal. 2018 Aug;48:43-57. doi: 10.1016/ Epub 2018 May 17.


Cardiac Optogenetics: 2018.

Boyle PM, Karathanos TV, Trayanova NA.

JACC Clin Electrophysiol. 2018 Feb;4(2):155-167. doi: 10.1016/j.jacep.2017.12.006. Epub 2018 Feb 1. Review.


Comparing Reentrant Drivers Predicted by Image-Based Computational Modeling and Mapped by Electrocardiographic Imaging in Persistent Atrial Fibrillation.

Boyle PM, Hakim JB, Zahid S, Franceschi WH, Murphy MJ, Vigmond EJ, Dubois R, Haïssaguerre M, Hocini M, Jaïs P, Trayanova NA, Cochet H.

Front Physiol. 2018 Apr 19;9:414. doi: 10.3389/fphys.2018.00414. eCollection 2018.


Personalized Imaging and Modeling Strategies for Arrhythmia Prevention and Therapy.

Trayanova NA, Boyle PM, Nikolov PP.

Curr Opin Biomed Eng. 2018 Mar;5:21-28. doi: 10.1016/j.cobme.2017.11.007.


Effect of KCNQ1 G229D mutation on cardiac pumping efficacy and reentrant dynamics in ventricles: Computational study.

Yuniarti AR, Setianto F, Marcellinus A, Hwang HJ, Choi SW, Trayanova N, Lim KM.

Int J Numer Method Biomed Eng. 2018 Jun;34(6):e2970. doi: 10.1002/cnm.2970. Epub 2018 Apr 11.


Relationship Between Fibrosis Detected on Late Gadolinium-Enhanced Cardiac Magnetic Resonance and Re-Entrant Activity Assessed With Electrocardiographic Imaging in Human Persistent Atrial Fibrillation.

Cochet H, Dubois R, Yamashita S, Al Jefairi N, Berte B, Sellal JM, Hooks D, Frontera A, Amraoui S, Zemoura A, Denis A, Derval N, Sacher F, Corneloup O, Latrabe V, Clément-Guinaudeau S, Relan J, Zahid S, Boyle PM, Trayanova NA, Bernus O, Montaudon M, Laurent F, Hocini M, Haïssaguerre M, Jaïs P.

JACC Clin Electrophysiol. 2018 Jan;4(1):17-29. doi: 10.1016/j.jacep.2017.07.019. Epub 2017 Nov 6.


Termination of re-entrant atrial tachycardia via optogenetic stimulation with optimized spatial targeting: insights from computational models.

Boyle PM, Murphy MJ, Karathanos TV, Zahid S, Blake RC 3rd, Trayanova NA.

J Physiol. 2018 Jan 15;596(2):181-196. doi: 10.1113/JP275264. Epub 2017 Dec 28.


β-adrenergic stimulation augments transmural dispersion of repolarization via modulation of delayed rectifier currents IKs and IKr in the human ventricle.

Kang C, Badiceanu A, Brennan JA, Gloschat C, Qiao Y, Trayanova NA, Efimov IR.

Sci Rep. 2017 Nov 21;7(1):15922. doi: 10.1038/s41598-017-16218-3.


Influence of LVAD function on mechanical unloading and electromechanical delay: a simulation study.

Heikhmakhtiar AK, Ryu AJ, Shim EB, Song KS, Trayanova NA, Lim KM.

Med Biol Eng Comput. 2018 May;56(5):911-921. doi: 10.1007/s11517-017-1730-y. Epub 2017 Nov 3.


Computational analysis of the effect of mitral and aortic regurgitation on the function of ventricular assist devices using 3D cardiac electromechanical model.

Kim YS, Yuniarti AR, Song KS, Trayanova NA, Shim EB, Lim KM.

Med Biol Eng Comput. 2018 May;56(5):889-898. doi: 10.1007/s11517-017-1727-6. Epub 2017 Oct 28.


Computational prediction of the effects of the intra-aortic balloon pump on heart failure with valvular regurgitation using a 3D cardiac electromechanical model.

Kim CH, Song KS, Trayanova NA, Lim KM.

Med Biol Eng Comput. 2018 May;56(5):853-863. doi: 10.1007/s11517-017-1731-x. Epub 2017 Oct 23.


Sensitivity of reentrant driver localization to electrophysiological parameter variability in image-based computational models of persistent atrial fibrillation sustained by a fibrotic substrate.

Deng D, Murphy MJ, Hakim JB, Franceschi WH, Zahid S, Pashakhanloo F, Trayanova NA, Boyle PM.

Chaos. 2017 Sep;27(9):093932. doi: 10.1063/1.5003340.


Plakophilin-2 is required for transcription of genes that control calcium cycling and cardiac rhythm.

Cerrone M, Montnach J, Lin X, Zhao YT, Zhang M, Agullo-Pascual E, Leo-Macias A, Alvarado FJ, Dolgalev I, Karathanos TV, Malkani K, Van Opbergen CJM, van Bavel JJA, Yang HQ, Vasquez C, Tester D, Fowler S, Liang F, Rothenberg E, Heguy A, Morley GE, Coetzee WA, Trayanova NA, Ackerman MJ, van Veen TAB, Valdivia HH, Delmar M.

Nat Commun. 2017 Jul 24;8(1):106. doi: 10.1038/s41467-017-00127-0.


Imaging-Based Simulations for Predicting Sudden Death and Guiding Ventricular Tachycardia Ablation.

Trayanova NA, Pashakhanloo F, Wu KC, Halperin HR.

Circ Arrhythm Electrophysiol. 2017 Jul;10(7). pii: e004743. doi: 10.1161/CIRCEP.117.004743. Review. No abstract available.

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