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Kras(G12D) and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung.
J Clin Invest. 2012 Dec;122(12):4388-400. doi: 10.1172/JCI64048. Epub 2012 Nov 12.
J Clin Invest. 2012.
PMID: 23143308
Free PMC article.
Sox2 activates cell proliferation and differentiation in the respiratory epithelium.
Tompkins DH, Besnard V, Lange AW, Keiser AR, Wert SE, Bruno MD, Whitsett JA.
Tompkins DH, et al.
Am J Respir Cell Mol Biol. 2011 Jul;45(1):101-10. doi: 10.1165/rcmb.2010-0149OC. Epub 2010 Sep 20.
Am J Respir Cell Mol Biol. 2011.
PMID: 20855650
Free PMC article.
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Sox2 is required for maintenance and differentiation of bronchiolar Clara, ciliated, and goblet cells.
Tompkins DH, Besnard V, Lange AW, Wert SE, Keiser AR, Smith AN, Lang R, Whitsett JA.
Tompkins DH, et al.
PLoS One. 2009 Dec 14;4(12):e8248. doi: 10.1371/journal.pone.0008248.
PLoS One. 2009.
PMID: 20011520
Free PMC article.
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