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Items: 1 to 20 of 67

1.

Pyruvate secreted from patient-derived cancer-associated fibroblasts supports survival of primary lymphoma cells.

Sakamoto A, Kunou S, Shimada K, Tsunoda M, Aoki T, Iriyama C, Tomita A, Nakamura S, Hayakawa F, Kiyoi H.

Cancer Sci. 2018 Nov 13. doi: 10.1111/cas.13873. [Epub ahead of print]

2.

T cell-intrinsic prostaglandin E2-EP2/EP4 signaling is critical in pathogenic TH17 cell-driven inflammation.

Lee J, Aoki T, Thumkeo D, Siriwach R, Yao C, Narumiya S.

J Allergy Clin Immunol. 2018 Jun 20. pii: S0091-6749(18)30896-0. doi: 10.1016/j.jaci.2018.05.036. [Epub ahead of print]

3.

Targeting macrophages to treat intracranial aneurysm.

Aoki T, Yamamoto R, Narumiya S.

Oncotarget. 2017 Sep 28;8(62):104704-104705. doi: 10.18632/oncotarget.21368. eCollection 2017 Dec 1. No abstract available.

4.

Prostaglandin E2-EP2 signaling as a node of chronic inflammation in the colon tumor microenvironment.

Aoki T, Narumiya S.

Inflamm Regen. 2017 Mar 1;37:4. doi: 10.1186/s41232-017-0036-7. eCollection 2017. Review.

5.

Macrophage Imaging of Cerebral Aneurysms with Ferumoxytol: an Exploratory Study in an Animal Model and in Patients.

Aoki T, Saito M, Koseki H, Tsuji K, Tsuji A, Murata K, Kasuya H, Morita A, Narumiya S, Nozaki K; MR Macrophage Imaging Study Investigators.

J Stroke Cerebrovasc Dis. 2017 Oct;26(10):2055-2064. doi: 10.1016/j.jstrokecerebrovasdis.2016.10.026. Epub 2017 Jul 31.

PMID:
28774792
6.

Dipeptidyl Peptidase-4 Inhibitor Anagliptin Prevents Intracranial Aneurysm Growth by Suppressing Macrophage Infiltration and Activation.

Ikedo T, Minami M, Kataoka H, Hayashi K, Nagata M, Fujikawa R, Higuchi S, Yasui M, Aoki T, Fukuda M, Yokode M, Miyamoto S.

J Am Heart Assoc. 2017 Jun 19;6(6). pii: e004777. doi: 10.1161/JAHA.116.004777.

7.

Prostaglandin E2 stimulates adaptive IL-22 production and promotes allergic contact dermatitis.

Robb CT, McSorley HJ, Lee J, Aoki T, Yu C, Crittenden S, Astier A, Felton JM, Parkinson N, Ayele A, Breyer RM, Anderton SM, Narumiya S, Rossi AG, Howie SE, Guttman-Yassky E, Weller RB, Yao C.

J Allergy Clin Immunol. 2018 Jan;141(1):152-162. doi: 10.1016/j.jaci.2017.04.045. Epub 2017 Jun 3.

8.

T cell function is dispensable for intracranial aneurysm formation and progression.

Miyata H, Koseki H, Takizawa K, Kasuya H, Nozaki K, Narumiya S, Aoki T.

PLoS One. 2017 Apr 24;12(4):e0175421. doi: 10.1371/journal.pone.0175421. eCollection 2017.

9.

A sphingosine-1-phosphate receptor type 1 agonist, ASP4058, suppresses intracranial aneurysm through promoting endothelial integrity and blocking macrophage transmigration.

Yamamoto R, Aoki T, Koseki H, Fukuda M, Hirose J, Tsuji K, Takizawa K, Nakamura S, Miyata H, Hamakawa N, Kasuya H, Nozaki K, Hirayama Y, Aramori I, Narumiya S.

Br J Pharmacol. 2017 Jul;174(13):2085-2101. doi: 10.1111/bph.13820. Epub 2017 May 27.

10.

Gut Microbiota Promotes Obesity-Associated Liver Cancer through PGE2-Mediated Suppression of Antitumor Immunity.

Loo TM, Kamachi F, Watanabe Y, Yoshimoto S, Kanda H, Arai Y, Nakajima-Takagi Y, Iwama A, Koga T, Sugimoto Y, Ozawa T, Nakamura M, Kumagai M, Watashi K, Taketo MM, Aoki T, Narumiya S, Oshima M, Arita M, Hara E, Ohtani N.

Cancer Discov. 2017 May;7(5):522-538. doi: 10.1158/2159-8290.CD-16-0932. Epub 2017 Feb 15.

11.

Prostaglandin E2-EP2-NF-κB signaling in macrophages as a potential therapeutic target for intracranial aneurysms.

Aoki T, Frȍsen J, Fukuda M, Bando K, Shioi G, Tsuji K, Ollikainen E, Nozaki K, Laakkonen J, Narumiya S.

Sci Signal. 2017 Feb 7;10(465). pii: eaah6037. doi: 10.1126/scisignal.aah6037.

PMID:
28174280
12.

Emetine elicits apoptosis of intractable B-cell lymphoma cells with MYC rearrangement through inhibition of glycolytic metabolism.

Aoki T, Shimada K, Sakamoto A, Sugimoto K, Morishita T, Kojima Y, Shimada S, Kato S, Iriyama C, Kuno S, Harada Y, Tomita A, Hayakawa F, Kiyoi H.

Oncotarget. 2017 Feb 21;8(8):13085-13098. doi: 10.18632/oncotarget.14393.

13.

Outcome differences between children and adolescents and young adults with non-Hodgkin lymphoma following stem cell transplantation.

Kobayashi R, Mitsui T, Fujita N, Osumi T, Aoki T, Aoki K, Suzuki R, Fukuda T, Miyamoto T, Kato K, Nakamae H, Goto H, Eto T, Inoue M, Mori T, Terui K, Onizuka M, Koh K, Koga Y, Ichinohe T, Sawada A, Atsuta Y, Suzumiya J.

Int J Hematol. 2017 Mar;105(3):369-376. doi: 10.1007/s12185-016-2120-1. Epub 2016 Oct 27.

PMID:
27787746
14.

Sustained expression of MCP-1 by low wall shear stress loading concomitant with turbulent flow on endothelial cells of intracranial aneurysm.

Aoki T, Yamamoto K, Fukuda M, Shimogonya Y, Fukuda S, Narumiya S.

Acta Neuropathol Commun. 2016 May 9;4(1):48. doi: 10.1186/s40478-016-0318-3.

15.

Preemptive Medicine for Cerebral Aneurysms.

Aoki T, Nozaki K.

Neurol Med Chir (Tokyo). 2016 Sep 15;56(9):552-68. doi: 10.2176/nmc.st.2016-0063. Epub 2016 Apr 6. Review.

16.

Lenalidomide in relapsed adult T-cell leukaemia-lymphoma or peripheral T-cell lymphoma (ATLL-001): a phase 1, multicentre, dose-escalation study.

Ogura M, Imaizumi Y, Uike N, Asou N, Utsunomiya A, Uchida T, Aoki T, Tsukasaki K, Taguchi J, Choi I, Maruyama D, Nosaka K, Chen N, Midorikawa S, Ohtsu T, Tobinai K.

Lancet Haematol. 2016 Mar;3(3):e107-18. doi: 10.1016/S2352-3026(15)00284-7. Epub 2016 Feb 12.

PMID:
26947199
17.

Safety and tolerability of ibrutinib monotherapy in Japanese patients with relapsed/refractory B cell malignancies.

Tobinai K, Ogura M, Ishizawa K, Suzuki T, Munakata W, Uchida T, Aoki T, Morishita T, Ushijima Y, Takahara S.

Int J Hematol. 2016 Jan;103(1):86-94. doi: 10.1007/s12185-015-1900-3. Epub 2015 Nov 20.

PMID:
26588924
18.

A case of MYH9 disorders caused by a novel mutation (p.K74E).

Kanematsu T, Suzuki N, Yoshida T, Kishimoto M, Aoki T, Ogawa M, Kagami Y, Kiyoi H, Matsushita T, Kunishima S.

Ann Hematol. 2016 Jan;95(1):161-3. doi: 10.1007/s00277-015-2506-9. Epub 2015 Sep 17. No abstract available.

PMID:
26382273
19.

Prostaglandin E2-EP4 signaling persistently amplifies CD40-mediated induction of IL-23 p19 expression through canonical and non-canonical NF-κB pathways.

Ma X, Aoki T, Narumiya S.

Cell Mol Immunol. 2016 Mar;13(2):240-50. doi: 10.1038/cmi.2015.70. Epub 2015 Jul 20.

20.

Definition of Prostaglandin E2-EP2 Signals in the Colon Tumor Microenvironment That Amplify Inflammation and Tumor Growth.

Ma X, Aoki T, Tsuruyama T, Narumiya S.

Cancer Res. 2015 Jul 15;75(14):2822-32. doi: 10.1158/0008-5472.CAN-15-0125. Epub 2015 May 27.

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