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Page 1
Molecular diversity through sugar scaffolds.
Drug Discov Today. 2003 Aug 1;8(15):701-9. doi: 10.1016/s1359-6446(03)02751-x.
Drug Discov Today. 2003.
PMID: 12927513
Review.
Pyrrolo[2,3-d]pyrimidines containing an extended 5-substituent as potent and selective inhibitors of lck II.
Burchat AF, Calderwood DJ, Hirst GC, Holman NJ, Johnston DN, Munschauer R, Rafferty P, Tometzki GB.
Burchat AF, et al. Among authors: tometzki gb.
Bioorg Med Chem Lett. 2000 Oct 2;10(19):2171-4. doi: 10.1016/s0960-894x(00)00442-x.
Bioorg Med Chem Lett. 2000.
PMID: 11012022
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Biological diversity from a structurally diverse library: systematically scanning conformational space using a pyranose scaffold.
Abbenante G, Becker B, Blanc S, Clark C, Condie G, Fraser G, Grathwohl M, Halliday J, Henderson S, Lam A, Liu L, Mann M, Muldoon C, Pearson A, Premraj R, Ramsdale T, Rossetti T, Schafer K, Le Thanh G, Tometzki G, Vari F, Verquin G, Waanders J, West M, Wimmer N, Yau A, Zuegg J, Meutermans W.
Abbenante G, et al. Among authors: tometzki g.
J Med Chem. 2010 Aug 12;53(15):5576-86. doi: 10.1021/jm1002777.
J Med Chem. 2010.
PMID: 20684600
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A versatile synthetic approach toward diversity libraries using monosaccharide scaffolds.
Thanh GL, Abbenante G, Adamson G, Becker B, Clark C, Condie G, Falzun T, Grathwohl M, Gupta P, Hanson M, Huynh N, Katavic P, Kuipers K, Lam A, Liu L, Mann M, Mason J, McKeveney D, Muldoon C, Pearson A, Rajaratnam P, Ryan S, Tometzki G, Verquin G, Waanders J, West M, Wilcox N, Wimmer N, Yau A, Zuegg J, Meutermans W.
Thanh GL, et al. Among authors: tometzki g.
J Org Chem. 2010 Jan 1;75(1):197-203. doi: 10.1021/jo9021919.
J Org Chem. 2010.
PMID: 19961235
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