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  • Showing results for Ticking[Title] AND right[Title] AND boxes[Title] AND classification[Title] AND patients[Title] AND suspected[Title] AND Lyme[Title] AND borreliosis[Title] AND academic[Title] AND center[Title] AND Netherlands[Title]. Your search for Ticking the right boxes: classification of patients suspected of Lyme borreliosis at an academic refrral center in the Netherlands retrieved no results.
Clin Microbiol Infect. 2015 Apr;21(4):368.e11-20. doi: 10.1016/j.cmi.2014.11.014. Epub 2014 Nov 22.

Ticking the right boxes: classification of patients suspected of Lyme borreliosis at an academic referral center in the Netherlands.

Author information

1
Center for Experimental and Molecular Medicine, Amsterdam, The Netherlands.
2
Amsterdam Multidisciplinary Lyme Borreliosis Center, Amsterdam, The Netherlands; Department of Neurology, Amsterdam, The Netherlands.
3
Amsterdam Multidisciplinary Lyme Borreliosis Center, Amsterdam, The Netherlands; Department of Rheumatology, Amsterdam, The Netherlands.
4
Amsterdam Multidisciplinary Lyme Borreliosis Center, Amsterdam, The Netherlands; Department of Psychiatry, Amsterdam, The Netherlands.
5
Amsterdam Multidisciplinary Lyme Borreliosis Center, Amsterdam, The Netherlands; Department of Infectious Diseases, Amsterdam, The Netherlands.
6
Amsterdam Multidisciplinary Lyme Borreliosis Center, Amsterdam, The Netherlands; Department of Dermatology, Amsterdam, The Netherlands.
7
Amsterdam Multidisciplinary Lyme Borreliosis Center, Amsterdam, The Netherlands; Department of Dermatology, Amsterdam, The Netherlands; Center for Infection and Immunity Amsterdam, Amsterdam, The Netherlands.
8
Amsterdam Multidisciplinary Lyme Borreliosis Center, Amsterdam, The Netherlands; Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
9
Center for Experimental and Molecular Medicine, Amsterdam, The Netherlands; Amsterdam Multidisciplinary Lyme Borreliosis Center, Amsterdam, The Netherlands; Department of Psychiatry, Amsterdam, The Netherlands. Electronic address: lyme@amc.uva.nl.

Abstract

To provide better care for patients suspected of having Lyme borreliosis (LB) we founded the Amsterdam Multidisciplinary Lyme borreliosis Center (AMLC). The AMLC reflects a collaborative effort of the departments of internal medicine/infectious diseases, rheumatology, neurology, dermatology, medical microbiology and psychiatry. In a retrospective case series, characteristics of 200 adult patients referred to the AMLC were recorded, and patients were classified as having LB, post-treatment LB syndrome (PTLBS), persistent Borrelia burgdorferi sensu lato (s.l.) infection despite antibiotic treatment or no LB. In addition, LB, PTLBS and persistent B. burgdorferi s.l. infection cases were classified as 'definite,' 'probable' or 'questionable.' Of the 200 patients, 120 (60%) did not have LB and 31 (16%) had a form of localized or disseminated LB, of which 12 were classified as definite, six as probable and 13 as questionable. In addition, 34 patients (17%) were diagnosed with PTLBS, of which 22 (11%) were probable and 12 (6%) questionable. A total of 15 patients (8%) were diagnosed with persistent B. burgdorferi s.l. infection, of which none was classified as definite, three as probable and 12 as questionable. In conclusion, in line with previous studies, the number of definite and probable (persisting) LB cases was low. The overall high number of questionable cases illustrates the fact that it can sometimes be challenging to either rule out or demonstrate an association with a B. burgdorferi s.l. infection, even in an academic setting. Finally, we were able to establish alternative diagnoses in a large proportion of patients.

KEYWORDS:

Chronic disease; Lyme disease; multidisciplinary communications; retrospective studies; tertiary care centers

PMID:
25658524
DOI:
10.1016/j.cmi.2014.11.014
[Indexed for MEDLINE]
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