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Items: 17

1.

Cathepsin S inhibition combines control of systemic and peripheral pathomechanisms of autoimmune tissue injury.

Tato M, Kumar SV, Liu Y, Mulay SR, Moll S, Popper B, Eberhard JN, Thomasova D, Rufer AC, Gruner S, Haap W, Hartmann G, Anders HJ.

Sci Rep. 2017 Jun 5;7(1):2775. doi: 10.1038/s41598-017-01894-y.

2.

MDM2 prevents spontaneous tubular epithelial cell death and acute kidney injury.

Thomasova D, Ebrahim M, Fleckinger K, Li M, Molnar J, Popper B, Liapis H, Kotb AM, Siegerist F, Endlich N, Anders HJ.

Cell Death Dis. 2016 Nov 24;7(11):e2482. doi: 10.1038/cddis.2016.390.

3.

Systems biology analysis reveals role of MDM2 in diabetic nephropathy.

Saito R, Rocanin-Arjo A, You YH, Darshi M, Van Espen B, Miyamoto S, Pham J, Pu M, Romoli S, Natarajan L, Ju W, Kretzler M, Nelson R, Ono K, Thomasova D, Mulay SR, Ideker T, D'Agati V, Beyret E, Belmonte JC, Anders HJ, Sharma K.

JCI Insight. 2016 Oct 20;1(17):e87877.

4.

Murine Double Minute-2 Inhibition Ameliorates Established Crescentic Glomerulonephritis.

Mulay SR, Romoli S, Desai J, Honarpisheh MM, Kumar SV, Anders HJ, Thomasova D.

Am J Pathol. 2016 Jun;186(6):1442-53. doi: 10.1016/j.ajpath.2016.01.017. Epub 2016 Apr 18.

PMID:
27102769
5.

Cytotoxicity of crystals involves RIPK3-MLKL-mediated necroptosis.

Mulay SR, Desai J, Kumar SV, Eberhard JN, Thomasova D, Romoli S, Grigorescu M, Kulkarni OP, Popper B, Vielhauer V, Zuchtriegel G, Reichel C, Bräsen JH, Romagnani P, Bilyy R, Munoz LE, Herrmann M, Liapis H, Krautwald S, Linkermann A, Anders HJ.

Nat Commun. 2016 Jan 28;7:10274. doi: 10.1038/ncomms10274.

6.

Cathepsin S Cleavage of Protease-Activated Receptor-2 on Endothelial Cells Promotes Microvascular Diabetes Complications.

Kumar Vr S, Darisipudi MN, Steiger S, Devarapu SK, Tato M, Kukarni OP, Mulay SR, Thomasova D, Popper B, Demleitner J, Zuchtriegel G, Reichel C, Cohen CD, Lindenmeyer MT, Liapis H, Moll S, Reid E, Stitt AW, Schott B, Gruner S, Haap W, Ebeling M, Hartmann G, Anders HJ.

J Am Soc Nephrol. 2016 Jun;27(6):1635-49. doi: 10.1681/ASN.2015020208. Epub 2015 Nov 13.

7.

PMA and crystal-induced neutrophil extracellular trap formation involves RIPK1-RIPK3-MLKL signaling.

Desai J, Kumar SV, Mulay SR, Konrad L, Romoli S, Schauer C, Herrmann M, Bilyy R, Müller S, Popper B, Nakazawa D, Weidenbusch M, Thomasova D, Krautwald S, Linkermann A, Anders HJ.

Eur J Immunol. 2016 Jan;46(1):223-9. doi: 10.1002/eji.201545605. Epub 2015 Nov 30.

8.

MDM2 beyond cancer: podoptosis, development, inflammation, and tissue regeneration.

Ebrahim M, Mulay SR, Anders HJ, Thomasova D.

Histol Histopathol. 2015 Nov;30(11):1271-82. doi: 10.14670/HH-11-636. Epub 2015 Jun 11. Review.

PMID:
26062755
9.

Neutrophil Extracellular Trap-Related Extracellular Histones Cause Vascular Necrosis in Severe GN.

Kumar SV, Kulkarni OP, Mulay SR, Darisipudi MN, Romoli S, Thomasova D, Scherbaum CR, Hohenstein B, Hugo C, Müller S, Liapis H, Anders HJ.

J Am Soc Nephrol. 2015 Oct;26(10):2399-413. doi: 10.1681/ASN.2014070673. Epub 2015 Feb 2.

10.

Cell cycle control in the kidney.

Thomasova D, Anders HJ.

Nephrol Dial Transplant. 2015 Oct;30(10):1622-30. doi: 10.1093/ndt/gfu395. Epub 2014 Dec 23. Review.

PMID:
25538161
11.

Murine Double Minute-2 Prevents p53-Overactivation-Related Cell Death (Podoptosis) of Podocytes.

Thomasova D, Bruns HA, Kretschmer V, Ebrahim M, Romoli S, Liapis H, Kotb AM, Endlich N, Anders HJ.

J Am Soc Nephrol. 2015 Jul;26(7):1513-23. doi: 10.1681/ASN.2014040345. Epub 2014 Oct 27.

12.

Toll-like receptor 4-induced IL-22 accelerates kidney regeneration.

Kulkarni OP, Hartter I, Mulay SR, Hagemann J, Darisipudi MN, Kumar Vr S, Romoli S, Thomasova D, Ryu M, Kobold S, Anders HJ.

J Am Soc Nephrol. 2014 May;25(5):978-89. doi: 10.1681/ASN.2013050528. Epub 2014 Jan 23.

13.

Podocyte loss involves MDM2-driven mitotic catastrophe.

Mulay SR, Thomasova D, Ryu M, Kulkarni OP, Migliorini A, Bruns H, Gröbmayr R, Lazzeri E, Lasagni L, Liapis H, Romagnani P, Anders HJ.

J Pathol. 2013 Jul;230(3):322-35. doi: 10.1002/path.4193.

PMID:
23749457
14.

Nrf2 signalling promotes ex vivo tubular epithelial cell survival and regeneration via murine double minute (MDM)-2.

Hagemann JH, Thomasova D, Mulay SR, Anders HJ.

Nephrol Dial Transplant. 2013 Aug;28(8):2028-37. doi: 10.1093/ndt/gft037. Epub 2013 Mar 8.

PMID:
23476038
15.
16.

Uromodulin triggers IL-1β-dependent innate immunity via the NLRP3 inflammasome.

Darisipudi MN, Thomasova D, Mulay SR, Brech D, Noessner E, Liapis H, Anders HJ.

J Am Soc Nephrol. 2012 Nov;23(11):1783-9. doi: 10.1681/ASN.2012040338. Epub 2012 Sep 20.

17.

MDM2 (murine double minute-2) links inflammation and tubular cell healing during acute kidney injury in mice.

Mulay SR, Thomasova D, Ryu M, Anders HJ.

Kidney Int. 2012 Jun;81(12):1199-211. doi: 10.1038/ki.2011.482. Epub 2012 Feb 1.

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