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Human adult HSCs can be discriminated from lineage-committed HPCs by the expression of endomucin.

Reckzeh K, Kizilkaya H, Helbo AS, Alrich ME, Deslauriers AG, Grover A, Rapin N, Asmar F, Grønbæk K, Porse B, Borregaard N, Vestweber D, Nerlov C, Theilgaard-Mönch K.

Blood Adv. 2018 Jul 10;2(13):1628-1632. doi: 10.1182/bloodadvances.2018015743. No abstract available.


Gut microbiota sustains hematopoiesis.

Theilgaard-Mönch K.

Blood. 2017 Feb 9;129(6):662-663. doi: 10.1182/blood-2016-12-754481. No abstract available.


The European Hematology Association Roadmap for European Hematology Research: a consensus document.

Engert A, Balduini C, Brand A, Coiffier B, Cordonnier C, Döhner H, de Wit TD, Eichinger S, Fibbe W, Green T, de Haas F, Iolascon A, Jaffredo T, Rodeghiero F, Salles G, Schuringa JJ; EHA Roadmap for European Hematology Research.

Haematologica. 2016 Feb;101(2):115-208. doi: 10.3324/haematol.2015.136739. Epub 2016 Jan 27.


ERG promotes the maintenance of hematopoietic stem cells by restricting their differentiation.

Knudsen KJ, Rehn M, Hasemann MS, Rapin N, Bagger FO, Ohlsson E, Willer A, Frank AK, Søndergaard E, Jendholm J, Thorén L, Lee J, Rak J, Theilgaard-Mönch K, Porse BT.

Genes Dev. 2015 Sep 15;29(18):1915-29. doi: 10.1101/gad.268409.115.


Cellular origin of prognostic chromosomal aberrations in AML patients.

Mora-Jensen H, Jendholm J, Rapin N, Andersen MK, Roug AS, Bagger FO, Bullinger L, Winther O, Borregaard N, Porse BT, Theilgaard-Mönch K.

Leukemia. 2015 Aug;29(8):1785-9. doi: 10.1038/leu.2015.30. Epub 2015 Feb 11. No abstract available.


Differential expression of granulopoiesis related genes in neutrophil subsets distinguished by membrane expression of CD177.

Hu N, Mora-Jensen H, Theilgaard-Mönch K, Doornbos-van der Meer B, Huitema MG, Stegeman CA, Heeringa P, Kallenberg CG, Westra J.

PLoS One. 2014 Jun 13;9(6):e99671. doi: 10.1371/journal.pone.0099671. eCollection 2014.


Comparing cancer vs normal gene expression profiles identifies new disease entities and common transcriptional programs in AML patients.

Rapin N, Bagger FO, Jendholm J, Mora-Jensen H, Krogh A, Kohlmann A, Thiede C, Borregaard N, Bullinger L, Winther O, Theilgaard-Mönch K, Porse BT.

Blood. 2014 Feb 6;123(6):894-904. doi: 10.1182/blood-2013-02-485771. Epub 2013 Dec 20.


MicroRNA profiling in human neutrophils during bone marrow granulopoiesis and in vivo exudation.

Larsen MT, Hother C, Häger M, Pedersen CC, Theilgaard-Mönch K, Borregaard N, Cowland JB.

PLoS One. 2013;8(3):e58454. doi: 10.1371/journal.pone.0058454. Epub 2013 Mar 12.


HemaExplorer: a database of mRNA expression profiles in normal and malignant haematopoiesis.

Bagger FO, Rapin N, Theilgaard-Mönch K, Kaczkowski B, Thoren LA, Jendholm J, Winther O, Porse BT.

Nucleic Acids Res. 2013 Jan;41(Database issue):D1034-9. doi: 10.1093/nar/gks1021. Epub 2012 Nov 9.


HemaExplorer: a Web server for easy and fast visualization of gene expression in normal and malignant hematopoiesis.

Bagger FO, Rapin N, Theilgaard-Mönch K, Kaczkowski B, Jendholm J, Winther O, Porse B.

Blood. 2012 Jun 28;119(26):6394-5. doi: 10.1182/blood-2012-05-427310. No abstract available.


Phosphorylation of serine 248 of C/EBPα is dispensable for myelopoiesis but its disruption leads to a low penetrant myeloid disorder with long latency.

Hasemann MS, Schuster MB, Frank AK, Theilgaard-Mönch K, Pedersen TÅ, Nerlov C, Porse BT.

PLoS One. 2012;7(6):e38841. doi: 10.1371/journal.pone.0038841. Epub 2012 Jun 8.


Technical advance: immunophenotypical characterization of human neutrophil differentiation.

Mora-Jensen H, Jendholm J, Fossum A, Porse B, Borregaard N, Theilgaard-Mönch K.

J Leukoc Biol. 2011 Sep;90(3):629-34. doi: 10.1189/jlb.0311123. Epub 2011 Jun 7. Erratum in: J Leukoc Biol. 2012 Mar;91(3):517. J Leukoc Biol. 2012 Mar;91(3):517. Borregaad, Niels [corrected to Borregaard, Niels].


Gene expression profiling in MDS and AML: potential and future avenues.

Theilgaard-Mönch K, Boultwood J, Ferrari S, Giannopoulos K, Hernandez-Rivas JM, Kohlmann A, Morgan M, Porse B, Tagliafico E, Zwaan CM, Wainscoat J, Van den Heuvel-Eibrink MM, Mills K, Bullinger L.

Leukemia. 2011 Jun;25(6):909-20. doi: 10.1038/leu.2011.48. Epub 2011 Mar 29. Review.


A conceptual framework for the identification of candidate drugs and drug targets in acute promyelocytic leukemia.

Marstrand TT, Borup R, Willer A, Borregaard N, Sandelin A, Porse BT, Theilgaard-Mönch K.

Leukemia. 2010 Jul;24(7):1265-75. doi: 10.1038/leu.2010.95. Epub 2010 May 27.


NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements.

Weischenfeldt J, Damgaard I, Bryder D, Theilgaard-Mönch K, Thoren LA, Nielsen FC, Jacobsen SE, Nerlov C, Porse BT.

Genes Dev. 2008 May 15;22(10):1381-96. doi: 10.1101/gad.468808.


Modeling of C/EBPalpha mutant acute myeloid leukemia reveals a common expression signature of committed myeloid leukemia-initiating cells.

Kirstetter P, Schuster MB, Bereshchenko O, Moore S, Dvinge H, Kurz E, Theilgaard-Mönch K, Månsson R, Pedersen TA, Pabst T, Schrock E, Porse BT, Jacobsen SE, Bertone P, Tenen DG, Nerlov C.

Cancer Cell. 2008 Apr;13(4):299-310. doi: 10.1016/j.ccr.2008.02.008.


High-dose erythropoietin alters platelet reactivity and bleeding time in rodents in contrast to the neuroprotective variant carbamyl-erythropoietin (CEPO).

Kirkeby A, Torup L, Bochsen L, Kjalke M, Abel K, Theilgaard-Monch K, Johansson PI, Bjørn SE, Gerwien J, Leist M.

Thromb Haemost. 2008 Apr;99(4):720-8. doi: 10.1160/TH07-03-0208.


The secretory leukocyte protease inhibitor (SLPI) and the secondary granule protein lactoferrin are synthesized in myelocytes, colocalize in subcellular fractions of neutrophils, and are coreleased by activated neutrophils.

Jacobsen LC, Sørensen OE, Cowland JB, Borregaard N, Theilgaard-Mönch K.

J Leukoc Biol. 2008 May;83(5):1155-64. doi: 10.1189/jlb.0706442. Epub 2008 Feb 19.


Mutation of C/EBPalpha predisposes to the development of myeloid leukemia in a retroviral insertional mutagenesis screen.

Hasemann MS, Damgaard I, Schuster MB, Theilgaard-Mönch K, Sørensen AB, Mrsic A, Krugers T, Ylstra B, Pedersen FS, Nerlov C, Porse BT.

Blood. 2008 Apr 15;111(8):4309-21. doi: 10.1182/blood-2007-06-097790. Epub 2008 Jan 22.


Neutrophil granules: a library of innate immunity proteins.

Borregaard N, Sørensen OE, Theilgaard-Mönch K.

Trends Immunol. 2007 Aug;28(8):340-5. Epub 2007 Jul 12. Review.


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