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Items: 9

1.

The effect of APOE, CETP, and PCSK9 polymorphisms on simvastatin response in Thai hypercholesterolemic patients.

Wanmasae S, Sirintronsopon W, Porntadavity S, Jeenduang N.

Cardiovasc Ther. 2017 Dec;35(6). doi: 10.1111/1755-5922.12302. Epub 2017 Sep 25.

PMID:
28851085
2.

The effect of genetic variation in PCSK9 on the LDL-cholesterol response to statin therapy.

Feng Q, Wei WQ, Chung CP, Levinson RT, Bastarache L, Denny JC, Stein CM.

Pharmacogenomics J. 2017 Mar;17(2):204-208. doi: 10.1038/tpj.2016.3. Epub 2016 Feb 23.

3.

Targeting the proprotein convertase subtilisin/kexin type 9 for the treatment of dyslipidemia and atherosclerosis.

Urban D, Pöss J, Böhm M, Laufs U.

J Am Coll Cardiol. 2013 Oct 15;62(16):1401-8. doi: 10.1016/j.jacc.2013.07.056. Epub 2013 Aug 21. Review.

5.

Leucine 10 allelic variant in signal peptide of PCSK9 increases the LDL cholesterol-lowering effect of statins in patients with familial hypercholesterolaemia.

Pisciotta L, Sallo R, Rabacchi C, Wunsch A, Calandra S, Bertolini S.

Nutr Metab Cardiovasc Dis. 2012 Oct;22(10):831-5. doi: 10.1016/j.numecd.2011.04.003. Epub 2011 Sep 14.

PMID:
21920719
6.

Genetic variation at the PCSK9 locus moderately lowers low-density lipoprotein cholesterol levels, but does not significantly lower vascular disease risk in an elderly population.

Polisecki E, Peter I, Robertson M, McMahon AD, Ford I, Packard C, Shepherd J, Jukema JW, Blauw GJ, Westendorp RG, de Craen AJ, Trompet S, Buckley BM, Murphy MB, Ordovas JM, Schaefer EJ; PROSPER Study Group.

Atherosclerosis. 2008 Sep;200(1):95-101. doi: 10.1016/j.atherosclerosis.2007.12.005. Epub 2008 Feb 8.

7.

Effect of ezetimibe coadministered with statins in genotype-confirmed heterozygous FH patients.

Pisciotta L, Fasano T, Bellocchio A, Bocchi L, Sallo R, Fresa R, Colangeli I, Cantafora A, Calandra S, Bertolini S.

Atherosclerosis. 2007 Oct;194(2):e116-22. Epub 2006 Nov 30.

PMID:
17140581
8.

Missense mutations in the PCSK9 gene are associated with hypocholesterolemia and possibly increased response to statin therapy.

Berge KE, Ose L, Leren TP.

Arterioscler Thromb Vasc Biol. 2006 May;26(5):1094-100. Epub 2006 Jan 19.

PMID:
16424354
9.

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