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Pan Afr Med J. 2018 Jun 13;30:125. doi: 10.11604/pamj.2018.30.125.14802. eCollection 2018.

Prevalence and risk factors of HTLV-1/2 and other blood borne infectious diseases among blood donors in Yaounde Central Hospital, Cameroon.

Author information

1
Department of Medical Microbiology and Immunology, School of Health Sciences-Catholic University of Central Africa, Yaoundé Cameroon.
2
Assistant Laboratory Technicians School, Yaoundé, Cameroon.
3
Military Health Research Center (CRESAR), Yaounde, Cameroon.

Abstract

Introduction:

Transfusion-transmissible infectious microorganisms including bacteria and viruses are among the greatest threats to blood safety for the recipient. The prevalence and risk factors of HTLV-1/2 and other blood borne infectious diseases were determined among blood donors in Yaounde Central Hospital, Cameroon.

Methods:

Design: cross sectional study. Setting: The blood bank unit of Yaounde Central Hospital, Cameroon. Subjects: a consecutive sample of 265 apparently healthy adult blood donors. Investigations: Search for the presence of hepatitis B surface antigen (AgHBs) and antibodies to human T-lymphotropic virus type 1 (anti-HTLV-1/2), human immunodeficiency virus (anti-HIV), hepatitis C virus (anti-HCV) and syphilis and to determine the epidemiological correlates, if any, in the occurrence of HTLV infection.

Results:

77 (29.05%) of the blood donors had serological evidence of infection with at least one pathogen and 4 (5.2%) had dual infections with HTLV-1/2. The overall prevalence of HTLV-1/2, HIV, HCV, HBV and syphilis were 5.7%, 5.3%, 2.6%, 11.7%, 3.8% respectively. Surgical history (Chi2=4.785; P=0.029), scarification (Chi2=6.359; P = 0.012), piercing (Chi2 = 16.353; P = 0.000) and intravenous drug use (Chi2 = 15.660; P = 0.000) were identified as risk factors for HTLV-1/2 infection.

Conclusion:

A relative high prevalence of viral infections and syphilis was recorded among the study participants especially for HTLV-1/2 for which none blood donation is routine screened in our set up. Therefore, a routine screen of blood prior to transfusion should include anti-HTLV-1/2 tests.

KEYWORDS:

HBV; HCV; HIV; HTLV-1/2; Prevalence; blood donors; risk factors; syphilis

PMID:
30374371
PMCID:
PMC6201601
DOI:
10.11604/pamj.2018.30.125.14802
[Indexed for MEDLINE]
Free PMC Article

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