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Items: 1 to 20 of 232

1.

Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis.

Ling SC, Dastidar SG, Tokunaga S, Ho WY, Lim K, Ilieva H, Parone PA, Tyan SH, Tse TM, Chang JC, Platoshyn O, Bui NB, Bui A, Vetto A, Sun S, McAlonis-Downes M, Han JS, Swing D, Kapeli K, Yeo GW, Tessarollo L, Marsala M, Shaw CE, Tucker-Kellogg G, La Spada AR, Lagier-Tourenne C, Da Cruz S, Cleveland DW.

Elife. 2019 Feb 12;8. pii: e40811. doi: 10.7554/eLife.40811.

2.

The Emergence and Functional Fitness of Memory CD4+ T Cells Require the Transcription Factor Thpok.

Ciucci T, Vacchio MS, Gao Y, Tomassoni Ardori F, Candia J, Mehta M, Zhao Y, Tran B, Pepper M, Tessarollo L, McGavern DB, Bosselut R.

Immunity. 2019 Jan 15;50(1):91-105.e4. doi: 10.1016/j.immuni.2018.12.019. Epub 2019 Jan 9.

PMID:
30638736
3.

Regulation of Kit Expression in Early Mouse Embryos and ES Cells.

Todaro F, Campolo F, Barrios F, Pellegrini M, Di Cesare S, Tessarollo L, Rossi P, Jannini EA, Dolci S.

Stem Cells. 2019 Mar;37(3):332-344. doi: 10.1002/stem.2960. Epub 2019 Jan 28.

PMID:
30566254
4.

ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS.

López-Erauskin J, Tadokoro T, Baughn MW, Myers B, McAlonis-Downes M, Chillon-Marinas C, Asiaban JN, Artates J, Bui AT, Vetto AP, Lee SK, Le AV, Sun Y, Jambeau M, Boubaker J, Swing D, Qiu J, Hicks GG, Ouyang Z, Fu XD, Tessarollo L, Ling SC, Parone PA, Shaw CE, Marsala M, Lagier-Tourenne C, Cleveland DW, Da Cruz S.

Neuron. 2018 Nov 21;100(4):816-830.e7. doi: 10.1016/j.neuron.2018.09.044. Epub 2018 Oct 18.

5.

Correction: Deficiency in Fpr2 results in reduced numbers of Lin- cKit+ Sca1+ myeloid progenitor cells.

Chen K, Tang P, Bao Z, He T, Xiang Y, Gong W, Yoshimura T, Le Y, Tessarollo L, Chen X, Wang JM.

J Biol Chem. 2018 Oct 19;293(42):16175. doi: 10.1074/jbc.AAC118.005966. No abstract available.

6.

Id1 Ablation Protects Hematopoietic Stem Cells from Stress-Induced Exhaustion and Aging.

Singh SK, Singh S, Gadomski S, Sun L, Pfannenstein A, Magidson V, Chen X, Kozlov S, Tessarollo L, Klarmann KD, Keller JR.

Cell Stem Cell. 2018 Aug 2;23(2):252-265.e8. doi: 10.1016/j.stem.2018.06.001. Epub 2018 Jun 28.

PMID:
30082068
7.

Deficiency in Fpr2 results in reduced numbers of Lin-cKit+Sca1+ myeloid progenitor cells.

Chen K, Tang P, Bao Z, He T, Xiang Y, Gong W, Yoshimura T, Le Y, Tessarollo L, Chen X, Wang JM.

J Biol Chem. 2018 Aug 31;293(35):13452-13463. doi: 10.1074/jbc.RA118.002683. Epub 2018 Jul 17. Erratum in: J Biol Chem. 2018 Oct 19;293(42):16175.

PMID:
30018139
8.

POGZ Is Required for Silencing Mouse Embryonic β-like Hemoglobin and Human Fetal Hemoglobin Expression.

Gudmundsdottir B, Gudmundsson KO, Klarmann KD, Singh SK, Sun L, Singh S, Du Y, Coppola V, Stockwin L, Nguyen N, Tessarollo L, Thorsteinsson L, Sigurjonsson OE, Gudmundsson S, Rafnar T, Tisdale JF, Keller JR.

Cell Rep. 2018 Jun 12;23(11):3236-3248. doi: 10.1016/j.celrep.2018.05.043.

9.

Regulation of BDNF Release by ARMS/Kidins220 through Modulation of Synaptotagmin-IV Levels.

López-Benito S, Sánchez-Sánchez J, Brito V, Calvo L, Lisa S, Torres-Valle M, Palko ME, Vicente-García C, Fernández-Fernández S, Bolaños JP, Ginés S, Tessarollo L, Arévalo JC.

J Neurosci. 2018 Jun 6;38(23):5415-5428. doi: 10.1523/JNEUROSCI.1653-17.2018. Epub 2018 May 16.

10.

Deletion of the endogenous TrkB.T1 receptor isoform restores the number of hippocampal CA1 parvalbumin-positive neurons and rescues long-term potentiation in pre-symptomatic mSOD1(G93A) ALS mice.

Quarta E, Fulgenzi G, Bravi R, Cohen EJ, Yanpallewar S, Tessarollo L, Minciacchi D.

Mol Cell Neurosci. 2018 Jun;89:33-41. doi: 10.1016/j.mcn.2018.03.010. Epub 2018 Mar 24.

PMID:
29580900
11.

The Antimicrobial Peptide CRAMP Is Essential for Colon Homeostasis by Maintaining Microbiota Balance.

Yoshimura T, McLean MH, Dzutsev AK, Yao X, Chen K, Huang J, Gong W, Zhou J, Xiang Y, H Badger J, O'hUigin C, Thovarai V, Tessarollo L, Durum SK, Trinchieri G, Bian XW, Wang JM.

J Immunol. 2018 Mar 15;200(6):2174-2185. doi: 10.4049/jimmunol.1602073. Epub 2018 Feb 12.

12.

Robust kinase- and age-dependent dopaminergic and norepinephrine neurodegeneration in LRRK2 G2019S transgenic mice.

Xiong Y, Neifert S, Karuppagounder SS, Liu Q, Stankowski JN, Lee BD, Ko HS, Lee Y, Grima JC, Mao X, Jiang H, Kang SU, Swing DA, Iacovitti L, Tessarollo L, Dawson TM, Dawson VL.

Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):1635-1640. doi: 10.1073/pnas.1712648115. Epub 2018 Jan 31.

13.

Zfp423/ZNF423 regulates cell cycle progression, the mode of cell division and the DNA-damage response in Purkinje neuron progenitors.

Casoni F, Croci L, Bosone C, D'Ambrosio R, Badaloni A, Gaudesi D, Barili V, Sarna JR, Tessarollo L, Cremona O, Hawkes R, Warming S, Consalez GG.

Development. 2017 Oct 15;144(20):3686-3697. doi: 10.1242/dev.155077. Epub 2017 Sep 11.

14.

CDK10 Mutations in Humans and Mice Cause Severe Growth Retardation, Spine Malformations, and Developmental Delays.

Windpassinger C, Piard J, Bonnard C, Alfadhel M, Lim S, Bisteau X, Blouin S, Ali NB, Ng AYJ, Lu H, Tohari S, Talib SZA, van Hul N, Caldez MJ, Van Maldergem L, Yigit G, Kayserili H, Youssef SA, Coppola V, de Bruin A, Tessarollo L, Choi H, Rupp V, Roetzer K, Roschger P, Klaushofer K, Altmüller J, Roy S, Venkatesh B, Ganger R, Grill F, Ben Chehida F, Wollnik B, Altunoglu U, Al Kaissi A, Reversade B, Kaldis P.

Am J Hum Genet. 2017 Sep 7;101(3):391-403. doi: 10.1016/j.ajhg.2017.08.003.

15.

Myc Regulates Chromatin Decompaction and Nuclear Architecture during B Cell Activation.

Kieffer-Kwon KR, Nimura K, Rao SSP, Xu J, Jung S, Pekowska A, Dose M, Stevens E, Mathe E, Dong P, Huang SC, Ricci MA, Baranello L, Zheng Y, Tomassoni Ardori F, Resch W, Stavreva D, Nelson S, McAndrew M, Casellas A, Finn E, Gregory C, St Hilaire BG, Johnson SM, Dubois W, Cosma MP, Batchelor E, Levens D, Phair RD, Misteli T, Tessarollo L, Hager G, Lakadamyali M, Liu Z, Floer M, Shroff H, Aiden EL, Casellas R.

Mol Cell. 2017 Aug 17;67(4):566-578.e10. doi: 10.1016/j.molcel.2017.07.013. Epub 2017 Aug 10.

16.

Emi2 Is Essential for Mouse Spermatogenesis.

Gopinathan L, Szmyd R, Low D, Diril MK, Chang HY, Coppola V, Liu K, Tessarollo L, Guccione E, van Pelt AMM, Kaldis P.

Cell Rep. 2017 Jul 18;20(3):697-708. doi: 10.1016/j.celrep.2017.06.033.

17.

Deubiquitinating enzyme VCIP135 dictates the duration of botulinum neurotoxin type A intoxication.

Tsai YC, Kotiya A, Kiris E, Yang M, Bavari S, Tessarollo L, Oyler GA, Weissman AM.

Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):E5158-E5166. doi: 10.1073/pnas.1621076114. Epub 2017 Jun 5.

18.

SorCS2-mediated NR2A trafficking regulates motor deficits in Huntington's disease.

Ma Q, Yang J, Milner TA, Vonsattel JG, Palko ME, Tessarollo L, Hempstead BL.

JCI Insight. 2017 May 4;2(9). pii: 88995. doi: 10.1172/jci.insight.88995. eCollection 2017 May 4.

19.

Eradication of Tumors through Simultaneous Ablation of CD276/B7-H3-Positive Tumor Cells and Tumor Vasculature.

Seaman S, Zhu Z, Saha S, Zhang XM, Yang MY, Hilton MB, Morris K, Szot C, Morris H, Swing DA, Tessarollo L, Smith SW, Degrado S, Borkin D, Jain N, Scheiermann J, Feng Y, Wang Y, Li J, Welsch D, DeCrescenzo G, Chaudhary A, Zudaire E, Klarmann KD, Keller JR, Dimitrov DS, St Croix B.

Cancer Cell. 2017 Apr 10;31(4):501-515.e8. doi: 10.1016/j.ccell.2017.03.005.

20.

Overexpression of Parkinson's Disease-Associated Mutation LRRK2 G2019S in Mouse Forebrain Induces Behavioral Deficits and α-Synuclein Pathology.

Xiong Y, Neifert S, Karuppagounder SS, Stankowski JN, Lee BD, Grima JC, Chen G, Ko HS, Lee Y, Swing D, Tessarollo L, Dawson TM, Dawson VL.

eNeuro. 2017 Mar 17;4(2). pii: ENEURO.0004-17.2017. doi: 10.1523/ENEURO.0004-17.2017. eCollection 2017 Mar-Apr.

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