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Targeted pharmacological therapy restores β-cell function for diabetes remission.
Sachs S, Bastidas-Ponce A, Tritschler S, Bakhti M, Böttcher A, Sánchez-Garrido MA, Tarquis-Medina M, Kleinert M, Fischer K, Jall S, Harger A, Bader E, Roscioni S, Ussar S, Feuchtinger A, Yesildag B, Neelakandhan A, Jensen CB, Cornu M, Yang B, Finan B, DiMarchi RD, Tschöp MH, Theis FJ, Hofmann SM, Müller TD, Lickert H. Sachs S, et al. Among authors: tarquis medina m. Nat Metab. 2020 Feb;2(2):192-209. doi: 10.1038/s42255-020-0171-3. Epub 2020 Feb 20. Nat Metab. 2020. PMID: 32694693
β-Cell Maturation and Identity in Health and Disease.
Salinno C, Cota P, Bastidas-Ponce A, Tarquis-Medina M, Lickert H, Bakhti M. Salinno C, et al. Among authors: tarquis medina m. Int J Mol Sci. 2019 Oct 30;20(21):5417. doi: 10.3390/ijms20215417. Int J Mol Sci. 2019. PMID: 31671683 Free PMC article. Review.
CD81 marks immature and dedifferentiated pancreatic β-cells.
Salinno C, Büttner M, Cota P, Tritschler S, Tarquis-Medina M, Bastidas-Ponce A, Scheibner K, Burtscher I, Böttcher A, Theis FJ, Bakhti M, Lickert H. Salinno C, et al. Among authors: tarquis medina m. Mol Metab. 2021 Jul;49:101188. doi: 10.1016/j.molmet.2021.101188. Epub 2021 Feb 11. Mol Metab. 2021. PMID: 33582383 Free PMC article.
Synaptotagmin-13 orchestrates pancreatic endocrine cell egression and islet morphogenesis.
Bakhti M, Bastidas-Ponce A, Tritschler S, Czarnecki O, Tarquis-Medina M, Nedvedova E, Jaki J, Willmann SJ, Scheibner K, Cota P, Salinno C, Boldt K, Horn N, Ueffing M, Burtscher I, Theis FJ, Coskun Ü, Lickert H. Bakhti M, et al. Among authors: tarquis medina m. Nat Commun. 2022 Aug 4;13(1):4540. doi: 10.1038/s41467-022-31862-8. Nat Commun. 2022. PMID: 35927244 Free PMC article.
Synaptotagmin-13 Is a Neuroendocrine Marker in Brain, Intestine and Pancreas.
Tarquis-Medina M, Scheibner K, González-García I, Bastidas-Ponce A, Sterr M, Jaki J, Schirge S, García-Cáceres C, Lickert H, Bakhti M. Tarquis-Medina M, et al. Int J Mol Sci. 2021 Nov 20;22(22):12526. doi: 10.3390/ijms222212526. Int J Mol Sci. 2021. PMID: 34830411 Free PMC article.
Generation of a Novel Nkx6-1 Venus Fusion Reporter Mouse Line.
Burtscher I, Tarquis-Medina M, Salinno C, Schirge S, Beckenbauer J, Bakhti M, Lickert H. Burtscher I, et al. Among authors: tarquis medina m. Int J Mol Sci. 2021 Mar 26;22(7):3434. doi: 10.3390/ijms22073434. Int J Mol Sci. 2021. PMID: 33810480 Free PMC article.
Author Correction: Targeted pharmacological therapy restores β-cell function for diabetes remission.
Sachs S, Bastidas-Ponce A, Tritschler S, Bakhti M, Böttcher A, Sánchez-Garrido MA, Tarquis-Medina M, Kleinert M, Fischer K, Jall S, Harger A, Bader E, Roscioni S, Ussar S, Feuchtinger A, Yesildag B, Neelakandhan A, Jensen CB, Cornu M, Yang B, Finan B, DiMarchi RD, Tschöp MH, Theis FJ, Hofmann SM, Müller TD, Lickert H. Sachs S, et al. Among authors: tarquis medina m. Nat Metab. 2020 Apr;2(4):380. doi: 10.1038/s42255-020-0201-1. Nat Metab. 2020. PMID: 33820985 No abstract available.
A point mutation in the Pdia6 gene results in loss of pancreatic β-cell identity causing overt diabetes.
Chhabra NF, Amend AL, Bastidas-Ponce A, Sabrautzki S, Tarquis-Medina M, Sachs S, Rubey M, Lorenz-Depiereux B, Feuchtinger A, Bakhti M, Lickert H, Przemeck GKH, Hrabě de Angelis M. Chhabra NF, et al. Among authors: tarquis medina m. Mol Metab. 2021 Dec;54:101334. doi: 10.1016/j.molmet.2021.101334. Epub 2021 Sep 4. Mol Metab. 2021. PMID: 34487921 Free PMC article.