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Items: 1 to 20 of 77

1.

AUTACs: Cargo-Specific Degraders Using Selective Autophagy.

Takahashi D, Moriyama J, Nakamura T, Miki E, Takahashi E, Sato A, Akaike T, Itto-Nakama K, Arimoto H.

Mol Cell. 2019 Dec 5;76(5):797-810.e10. doi: 10.1016/j.molcel.2019.09.009. Epub 2019 Oct 9.

PMID:
31606272
2.

Rational Design of a Dual-Reactivity-Based Fluorescent Probe for Visualizing Intracellular HSNO.

Chen W, Matsunaga T, Neill DL, Yang CT, Akaike T, Xian M.

Angew Chem Int Ed Engl. 2019 Nov 4;58(45):16067-16070. doi: 10.1002/anie.201908950. Epub 2019 Sep 24.

PMID:
31479578
3.

Long-lasting blood pressure lowering effects of nitrite are NO-independent and mediated by hydrogen peroxide, persulfides and oxidation of protein kinase G 1α redox signaling.

Feelisch M, Akaike T, Griffiths K, Ida T, Prysyahna O, Goodwin JJ, Gollop ND, Fernandez BO, Minnion M, Cortese-Krott MM, Borgognone A, Hayes RM, Eaton P, Frenneaux MP, Madhani M.

Cardiovasc Res. 2019 Jul 31. pii: cvz202. doi: 10.1093/cvr/cvz202. [Epub ahead of print]

PMID:
31372656
4.

Mitochondrial cysteinyl-tRNA synthetase is expressed via alternative transcriptional initiation regulated by energy metabolism in yeast cells.

Nishimura A, Nasuno R, Yoshikawa Y, Jung M, Ida T, Matsunaga T, Morita M, Takagi H, Motohashi H, Akaike T.

J Biol Chem. 2019 Sep 13;294(37):13781-13788. doi: 10.1074/jbc.RA119.009203. Epub 2019 Jul 26.

PMID:
31350340
5.

Depolysulfidation of Drp1 induced by low-dose methylmercury exposure increases cardiac vulnerability to hemodynamic overload.

Nishimura A, Shimoda K, Tanaka T, Toyama T, Nishiyama K, Shinkai Y, Numaga-Tomita T, Yamazaki D, Kanda Y, Akaike T, Kumagai Y, Nishida M.

Sci Signal. 2019 Jun 25;12(587). pii: eaaw1920. doi: 10.1126/scisignal.aaw1920.

PMID:
31239323
6.

Data-Driven Identification of Hydrogen Sulfide Scavengers.

Yang CT, Wang Y, Marutani E, Ida T, Ni X, Xu S, Chen W, Zhang H, Akaike T, Ichinose F, Xian M.

Angew Chem Int Ed Engl. 2019 Aug 5;58(32):10898-10902. doi: 10.1002/anie.201905580. Epub 2019 Jul 11.

PMID:
31194894
7.

Oxidation of PKGIα mediates an endogenous adaptation to pulmonary hypertension.

Rudyk O, Rowan A, Prysyazhna O, Krasemann S, Hartmann K, Zhang M, Shah AM, Ruppert C, Weiss A, Schermuly RT, Ida T, Akaike T, Zhao L, Eaton P.

Proc Natl Acad Sci U S A. 2019 Jun 25;116(26):13016-13025. doi: 10.1073/pnas.1904064116. Epub 2019 Jun 11.

8.

Environmental Electrophile-Mediated Toxicity in Mice Lacking Nrf2, CSE, or Both.

Akiyama M, Unoki T, Shinkai Y, Ishii I, Ida T, Akaike T, Yamamoto M, Kumagai Y.

Environ Health Perspect. 2019 Jun;127(6):67002. doi: 10.1289/EHP4949. Epub 2019 Jun 5.

9.

Nitrosative stress in patients with asthma-chronic obstructive pulmonary disease overlap.

Kyogoku Y, Sugiura H, Ichikawa T, Numakura T, Koarai A, Yamada M, Fujino N, Tojo Y, Onodera K, Tanaka R, Sato K, Sano H, Yamanaka S, Itakura K, Mitsune A, Tamada T, Akaike T, Ichinose M.

J Allergy Clin Immunol. 2019 Oct;144(4):972-983.e14. doi: 10.1016/j.jaci.2019.04.023. Epub 2019 May 9.

PMID:
31077687
10.

Distribution of Polysulfide in Human Biological Fluids and Their Association with Amylase and Sperm Activities.

Ikeda M, Ishima Y, Chuang VTG, Sakai M, Osafune H, Ando H, Shimizu T, Okuhira K, Watanabe H, Maruyama T, Otagiri M, Akaike T, Ishida T.

Molecules. 2019 Apr 30;24(9). pii: E1689. doi: 10.3390/molecules24091689.

11.

Enhanced Cellular Polysulfides Negatively Regulate TLR4 Signaling and Mitigate Lethal Endotoxin Shock.

Zhang T, Ono K, Tsutsuki H, Ihara H, Islam W, Akaike T, Sawa T.

Cell Chem Biol. 2019 May 16;26(5):686-698.e4. doi: 10.1016/j.chembiol.2019.02.003. Epub 2019 Mar 7.

PMID:
30853417
12.

The active-site cysteine residue of Ca2+/calmodulin-dependent protein kinase I is protected from irreversible modification via generation of polysulfidation.

Takata T, Tsukuda A, Tsuchiya Y, Akaike T, Watanabe Y.

Nitric Oxide. 2019 May 1;86:68-75. doi: 10.1016/j.niox.2019.02.008. Epub 2019 Mar 4.

PMID:
30844494
13.

8-Nitro-cGMP attenuates context-dependent fear memory in mice.

Kishimoto Y, Kasamatsu S, Yanai S, Endo S, Akaike T, Ihara H.

Biochem Biophys Res Commun. 2019 Mar 26;511(1):141-147. doi: 10.1016/j.bbrc.2019.01.138. Epub 2019 Feb 14.

PMID:
30773263
14.

The Uptake and Release of Polysulfur Cysteine Species by Cells: Physiological and Toxicological Implications.

Lin J, Akiyama M, Bica I, Long FT, Henderson CF, Goddu RN, Suarez V, Baker B, Ida T, Shinkai Y, Nagy P, Akaike T, Fukuto JM, Kumagai Y.

Chem Res Toxicol. 2019 Mar 18;32(3):447-455. doi: 10.1021/acs.chemrestox.8b00340. Epub 2019 Feb 7.

PMID:
30681327
15.

Polysulfide stabilization by tyrosine and hydroxyphenyl-containing derivatives that is important for a reactive sulfur metabolomics analysis.

Hamid HA, Tanaka A, Ida T, Nishimura A, Matsunaga T, Fujii S, Morita M, Sawa T, Fukuto JM, Nagy P, Tsutsumi R, Motohashi H, Ihara H, Akaike T.

Redox Biol. 2019 Feb;21:101096. doi: 10.1016/j.redox.2019.101096. Epub 2019 Jan 2.

16.

Hypoxia-induced interaction of filamin with Drp1 causes mitochondrial hyperfission-associated myocardial senescence.

Nishimura A, Shimauchi T, Tanaka T, Shimoda K, Toyama T, Kitajima N, Ishikawa T, Shindo N, Numaga-Tomita T, Yasuda S, Sato Y, Kuwahara K, Kumagai Y, Akaike T, Ide T, Ojida A, Mori Y, Nishida M.

Sci Signal. 2018 Nov 13;11(556). pii: eaat5185. doi: 10.1126/scisignal.aat5185.

PMID:
30425165
17.

Production of 8-nitro-cGMP in osteocytic cells and its upregulation by parathyroid hormone and prostaglandin E2.

Nagayama K, Miyamoto Y, Kaneko K, Yoshimura K, Sasa K, Akaike T, Fujii S, Izumida E, Uyama R, Chikazu D, Maki K, Kamijo R.

In Vitro Cell Dev Biol Anim. 2019 Jan;55(1):45-51. doi: 10.1007/s11626-018-0304-0. Epub 2018 Nov 5.

PMID:
30397855
18.

SNAP-25 S-Guanylation and SNARE Complex Formation.

Kishimoto Y, Akaike T, Ihara H.

Methods Mol Biol. 2019;1860:163-173. doi: 10.1007/978-1-4939-8760-3_9.

PMID:
30317503
19.

Reactive Persulfides from Salmonella Typhimurium Downregulate Autophagy-Mediated Innate Immunity in Macrophages by Inhibiting Electrophilic Signaling.

Khan S, Fujii S, Matsunaga T, Nishimura A, Ono K, Ida T, Ahmed KA, Okamoto T, Tsutsuki H, Sawa T, Akaike T.

Cell Chem Biol. 2018 Nov 15;25(11):1403-1413.e4. doi: 10.1016/j.chembiol.2018.08.007. Epub 2018 Sep 6.

20.

Speciation of reactive sulfur species and their reactions with alkylating agents: do we have any clue about what is present inside the cell?

Bogdándi V, Ida T, Sutton TR, Bianco C, Ditrói T, Koster G, Henthorn HA, Minnion M, Toscano JP, van der Vliet A, Pluth MD, Feelisch M, Fukuto JM, Akaike T, Nagy P.

Br J Pharmacol. 2019 Feb;176(4):646-670. doi: 10.1111/bph.14394. Epub 2018 Aug 23.

PMID:
29909607

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