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Antibodies targeting the fusion peptide on the HIV envelope provide protection to rhesus macaques against mucosal SHIV challenge.
Sci Transl Med. 2024 Jan 17;16(730):eadh9039. doi: 10.1126/scitranslmed.adh9039. Epub 2024 Jan 17.
Sci Transl Med. 2024.
PMID: 38232141
Structural basis of glycan276-dependent recognition by HIV-1 broadly neutralizing antibodies.
Cottrell CA, Manne K, Kong R, Wang S, Zhou T, Chuang GY, Edwards RJ, Henderson R, Janowska K, Kopp M, Lin BC, Louder MK, Olia AS, Rawi R, Shen CH, Taft JD, Torres JL, Wu NR, Zhang B, Doria-Rose NA, Cohen MS, Haynes BF, Shapiro L, Ward AB, Acharya P, Mascola JR, Kwong PD.
Cottrell CA, et al. Among authors: taft jd.
Cell Rep. 2021 Nov 2;37(5):109922. doi: 10.1016/j.celrep.2021.109922.
Cell Rep. 2021.
PMID: 34731616
Free PMC article.
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Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody.
Kong R, Xu K, Zhou T, Acharya P, Lemmin T, Liu K, Ozorowski G, Soto C, Taft JD, Bailer RT, Cale EM, Chen L, Choi CW, Chuang GY, Doria-Rose NA, Druz A, Georgiev IS, Gorman J, Huang J, Joyce MG, Louder MK, Ma X, McKee K, O'Dell S, Pancera M, Yang Y, Blanchard SC, Mothes W, Burton DR, Koff WC, Connors M, Ward AB, Kwong PD, Mascola JR.
Kong R, et al. Among authors: taft jd.
Science. 2016 May 13;352(6287):828-33. doi: 10.1126/science.aae0474.
Science. 2016.
PMID: 27174988
Free PMC article.
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A Neutralizing Antibody Recognizing Primarily N-Linked Glycan Targets the Silent Face of the HIV Envelope.
Zhou T, Zheng A, Baxa U, Chuang GY, Georgiev IS, Kong R, O'Dell S, Shahzad-Ul-Hussan S, Shen CH, Tsybovsky Y, Bailer RT, Gift SK, Louder MK, McKee K, Rawi R, Stevenson CH, Stewart-Jones GBE, Taft JD, Waltari E, Yang Y, Zhang B, Shivatare SS, Shivatare VS, Lee CD, Wu CY; NISC Comparative Sequencing Program; Mullikin JC, Bewley CA, Burton DR, Polonis VR, Shapiro L, Wong CH, Mascola JR, Kwong PD, Wu X.
Zhou T, et al. Among authors: taft jd.
Immunity. 2018 Mar 20;48(3):500-513.e6. doi: 10.1016/j.immuni.2018.02.013. Epub 2018 Mar 13.
Immunity. 2018.
PMID: 29548671
Free PMC article.
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Dioxin Exposure Alters Molecular and Morphological Responses to Thyroid Hormone in Xenopus laevis Cultured Cells and Prometamorphic Tadpoles.
Taft JD, Colonnetta MM, Schafer RE, Plick N, Powell WH.
Taft JD, et al.
Toxicol Sci. 2018 Jan 1;161(1):196-206. doi: 10.1093/toxsci/kfx213.
Toxicol Sci. 2018.
PMID: 29294139
Free PMC article.
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Improving neutralization potency and breadth by combining broadly reactive HIV-1 antibodies targeting major neutralization epitopes.
Kong R, Louder MK, Wagh K, Bailer RT, deCamp A, Greene K, Gao H, Taft JD, Gazumyan A, Liu C, Nussenzweig MC, Korber B, Montefiori DC, Mascola JR.
Kong R, et al. Among authors: taft jd.
J Virol. 2015 Mar;89(5):2659-71. doi: 10.1128/JVI.03136-14. Epub 2014 Dec 17.
J Virol. 2015.
PMID: 25520506
Free PMC article.
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Sendai virus, an RNA virus with no risk of genomic integration, delivers CRISPR/Cas9 for efficient gene editing.
Park A, Hong P, Won ST, Thibault PA, Vigant F, Oguntuyo KY, Taft JD, Lee B.
Park A, et al. Among authors: taft jd.
Mol Ther Methods Clin Dev. 2016 Aug 24;3:16057. doi: 10.1038/mtm.2016.57. eCollection 2016.
Mol Ther Methods Clin Dev. 2016.
PMID: 27606350
Free PMC article.
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