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See also: TP53 tumor protein p53 in the Gene database

tp53 in Homo sapiensRattus norvegicusDanio rerioAll 160 Gene records

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Items: 1 to 20 of 15375


Phase I study of the checkpoint kinase 1 inhibitor GDC-0575 in combination with gemcitabine in patients with refractory solid tumors.

Italiano A, Infante JR, Shapiro GI, Moore KN, LoRusso PM, Hamilton E, Cousin S, Toulmonde M, Postel-Vinay S, Tolaney S, Blackwood EM, Mahrus S, Peale FV, Lu X, Moein A, Epler J, DuPree K, Tagen M, Murray ER, Schutzman JL, Lauchle JO, Hollebecque A, Soria JC.

Ann Oncol. 2018 Feb 23. doi: 10.1093/annonc/mdy076. [Epub ahead of print]


TP53 gain-of-function mutation promotes inflammation in glioblastoma.

Ham SW, Jeon HY, Jin X, Kim EJ, Kim JK, Shin YJ, Lee Y, Kim SH, Lee SY, Seo S, Park MG, Kim HM, Nam DH, Kim H.

Cell Death Differ. 2018 May 21. doi: 10.1038/s41418-018-0126-3. [Epub ahead of print]


Somatic hematopoietic TP53 mosaicism in women with breast cancer exposed to ionizing radiation.

Melnov S, Murphy P, Foley T, Nadyrov E, Kipen V, Leushev B, Modugno F.

Breast J. 2018 May 21. doi: 10.1111/tbj.13056. [Epub ahead of print] No abstract available.


Valproic acid treatment response in vitro is determined by TP53 status in medulloblastoma.

Mascaro-Cordeiro B, Oliveira ID, Tesser-Gamba F, Pavon LF, Saba-Silva N, Cavalheiro S, Dastoli P, Toledo SRC.

Childs Nerv Syst. 2018 May 22. doi: 10.1007/s00381-018-3817-7. [Epub ahead of print]


Prevalence of deleterious mutations among patients with breast cancer referred for multigene panel testing in a Romanian population.

Goidescu IG, Caracostea G, Eniu DT, Stamatian FV.

Clujul Med. 2018;91(2):157-165. doi: 10.15386/cjmed-894. Epub 2018 Apr 25.


Identification of Novel Somatic <i>TP53</i> Mutations in Patients with High-Grade Serous Ovarian Cancer (HGSOC) Using Next-Generation Sequencing (NGS).

Garziera M, Cecchin E, Canzonieri V, Sorio R, Giorda G, Scalone S, De Mattia E, Roncato R, Gagno S, Poletto E, Romanato L, Sartor F, Polesel J, Toffoli G.

Int J Mol Sci. 2018 May 18;19(5). pii: E1510. doi: 10.3390/ijms19051510.


Optimization to detect TP53 mutations in circulating cell-free tumor DNA from patients with serous epithelial ovarian cancer.

Park YR, Kim YM, Lee SW, Lee HY, Lee GE, Lee JE, Kim YT.

Obstet Gynecol Sci. 2018 May;61(3):328-336. doi: 10.5468/ogs.2018.61.3.328. Epub 2018 May 8.


Estrogen receptor positive breast tumors resist chemotherapy by the overexpression of P53 in Cancer Stem Cells.

Ashour F, Awwad MH, Sharawy HEL, Kamal M.

J Egypt Natl Canc Inst. 2018 May 17. pii: S1110-0362(18)30024-4. doi: 10.1016/j.jnci.2018.04.002. [Epub ahead of print]


[Prognostic significance of CLL-IPI for Chinese patients with chronic lymphocytic leukemia].

Zhu HY, Wang L, Qiao J, Zou YX, Xia Y, Wu W, Cao L, Liang JH, Fan L, Xu W, Li JY.

Zhonghua Xue Ye Xue Za Zhi. 2018 May 14;39(5):392-397. doi: 10.3760/cma.j.issn.0253-2727.2018.05.009. Chinese.


Genetic mutation analysis of the malignant transformation of sinonasal inverted papilloma by targeted amplicon sequencing.

Yasukawa S, Kano S, Hatakeyama H, Nakamaru Y, Takagi D, Mizumachi T, Suzuki M, Suzuki T, Nakazono A, Tanaka S, Nishihara H, Homma A.

Int J Clin Oncol. 2018 May 19. doi: 10.1007/s10147-018-1296-1. [Epub ahead of print]


The TP53-Induced Glycolysis and Apoptosis Regulator mediates cooperation between HTLV-1 p30<sup>II</sup> and the retroviral oncoproteins Tax and HBZ and is highly expressed in an in vivo xenograft model of HTLV-1-induced lymphoma.

Hutchison T, Malu A, Yapindi L, Bergeson R, Peck K, Romeo M, Harrod C, Pope J, Smitherman L, Gwinn W, Ratner L, Yates C, Harrod R.

Virology. 2018 May 16;520:39-58. doi: 10.1016/j.virol.2018.05.007. [Epub ahead of print]


The clinical implications of G1-G6 transcriptomic signature and 5-gene score in Korean patients with hepatocellular carcinoma.

Ahn SM, Haq F, Park I, Nault JC, Zucman-Rossi J, Yu E.

BMC Cancer. 2018 May 18;18(1):571. doi: 10.1186/s12885-018-4192-1.


Improved, ACMG-Compliant, in silico prediction of pathogenicity for missense substitutions encoded by TP53 variants.

Fortuno C, James PA, Young EL, Feng B, Olivier M, Pesaran T, Tavtigian SV, Spurdle AB.

Hum Mutat. 2018 May 18. doi: 10.1002/humu.23553. [Epub ahead of print]


STK11/LKB1 Mutations and PD-1 Inhibitor Resistance in KRAS-Mutant Lung Adenocarcinoma.

Skoulidis F, Goldberg ME, Greenawalt DM, Hellmann MD, Awad MM, Gainor JF, Schrock AB, Hartmaier RJ, Trabucco SE, Gay L, Ali SM, Elvin JA, Singal G, Ross JS, Fabrizio D, Szabo PM, Chang H, Sasson A, Srinivasan S, Kirov S, Szustakowski J, Vitazka P, Edwards R, Bufill JA, Sharma N, Ou SI, Peled N, Spigel DR, Rizvi H, Jimenez Aguilar E, Carter BW, Erasmus J, Halpenny DF, Plodkowski AJ, Long NM, Nishino M, Denning WL, Galan-Cobo A, Hamdi H, Hirz T, Tong P, Wang J, Rodriguez-Canales J, Villalobos PA, Parra ER, Kalhor N, Sholl LM, Sauter JL, Jungbluth AA, Mino-Kenudson M, Azimi R, Elamin YY, Zhang J, Leonardi GC, Jiang F, Wong KK, Lee JJ, Papadimitrakopoulou VA, Wistuba II, Miller VA, Frampton GM, Wolchok JD, Shaw AT, Jänne PA, Stephens PJ, Rudin CM, Geese WJ, Albacker LA, Heymach JV.

Cancer Discov. 2018 May 17. pii: CD-18-0099. doi: 10.1158/2159-8290.CD-18-0099. [Epub ahead of print]


DNA Content Analysis of Colorectal Serrated Lesions Detects an Aneuploid Subset of Inflammatory Bowel Disease-Associated Serrated Epithelial Change and Traditional Serrated Adenomas.

Choi WT, Wen KW, Rabinovitch PS, Huang D, Mattis AN, Gill RM.

Histopathology. 2018 May 17. doi: 10.1111/his.13652. [Epub ahead of print]


Prevalence of germline BRCA mutations among women with carcinoma of the peritoneum or fallopian tube.

Choi MC, Bae JS, Jung SG, Park H, Joo WD, Song SH, Lee C, Kim JH, Lee KC, Lee S, Lee JH.

J Gynecol Oncol. 2018 Mar 26. doi: 10.3802/jgo.2018.29.e43. [Epub ahead of print]


NADPH ameliorates MPTP-induced dopaminergic neurodegeneration through inhibiting p38MAPK activation.

Zhou JS, Zhu Z, Wu F, Zhou Y, Sheng R, Wu JC, Qin ZH.

Acta Pharmacol Sin. 2018 May 16. doi: 10.1038/s41401-018-0003-0. [Epub ahead of print]


TIGAR knockdown enhanced the anticancer effect of aescin via regulating autophagy and apoptosis in colorectal cancer cells.

Li B, Wang Z, Xie JM, Wang G, Qian LQ, Guan XM, Shen XP, Qin ZH, Shen GH, Li XQ, Gao QG.

Acta Pharmacol Sin. 2018 May 16. doi: 10.1038/s41401-018-0001-2. [Epub ahead of print]


A new method of identifying glioblastoma subtypes and creation of corresponding animal models.

Zhou X, Li G, An S, Li WX, Yang H, Guo Y, Dai Z, Dai S, Zheng J, Huang J, Iavarone A, Zhao X.

Oncogene. 2018 May 17. doi: 10.1038/s41388-018-0305-1. [Epub ahead of print]


Germline mutation in the TP53 gene in uveal melanoma.

Hajkova N, Hojny J, Nemejcova K, Dundr P, Ulrych J, Jirsova K, Glezgova J, Ticha I.

Sci Rep. 2018 May 16;8(1):7618. doi: 10.1038/s41598-018-26040-0.

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