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Items: 1 to 20 of 124

1.

Universal Principled Review: A Community-Driven Method to Improve Peer Review.

Krummel M, Blish C, Kuhns M, Cadwell K, Oberst A, Goldrath A, Ansel KM, Chi H, O'Connell R, Wherry EJ, Pepper M; Future Immunology Consortium.

Cell. 2019 Dec 12;179(7):1441-1445. doi: 10.1016/j.cell.2019.11.029.

PMID:
31835023
2.

T Cell Metabolism in a State of Flux.

Varanasi SK, Ma S, Kaech SM.

Immunity. 2019 Nov 19;51(5):783-785. doi: 10.1016/j.immuni.2019.10.012.

PMID:
31747577
3.

O-GlcNAcase targets pyruvate kinase M2 to regulate tumor growth.

Singh JP, Qian K, Lee JS, Zhou J, Han X, Zhang B, Ong Q, Ni W, Jiang M, Ruan HB, Li MD, Zhang K, Ding Z, Lee P, Singh K, Wu J, Herzog RI, Kaech S, Wendel HG, Yates JR 3rd, Han W, Sherwin RS, Nie Y, Yang X.

Oncogene. 2019 Sep 9. doi: 10.1038/s41388-019-0975-3. [Epub ahead of print]

PMID:
31501520
4.

Proteomics of Melanoma Response to Immunotherapy Reveals Mitochondrial Dependence.

Harel M, Ortenberg R, Varanasi SK, Mangalhara KC, Mardamshina M, Markovits E, Baruch EN, Tripple V, Arama-Chayoth M, Greenberg E, Shenoy A, Ayasun R, Knafo N, Xu S, Anafi L, Yanovich-Arad G, Barnabas GD, Ashkenazi S, Besser MJ, Schachter J, Bosenberg M, Shadel GS, Barshack I, Kaech SM, Markel G, Geiger T.

Cell. 2019 Sep 19;179(1):236-250.e18. doi: 10.1016/j.cell.2019.08.012. Epub 2019 Sep 5.

PMID:
31495571
5.

Tick-TOX, it's time for T cell exhaustion.

Mann TH, Kaech SM.

Nat Immunol. 2019 Sep;20(9):1092-1094. doi: 10.1038/s41590-019-0478-y. No abstract available.

PMID:
31427776
6.

The landscape of novel and complementary targets for immunotherapy: an analysis of gene expression in the tumor microenvironment.

Gaffney SG, Perry EB, Chen PM, Greenstein A, Kaech SM, Townsend JP.

Oncotarget. 2019 Jul 16;10(44):4532-4545. doi: 10.18632/oncotarget.27027. eCollection 2019 Jul 16.

7.

Tumor regression mediated by oncogene withdrawal or erlotinib stimulates infiltration of inflammatory immune cells in EGFR mutant lung tumors.

Ayeni D, Miller B, Kuhlmann A, Ho PC, Robles-Oteiza C, Gaefele M, Levy S, de Miguel FJ, Perry C, Guan T, Krystal G, Lockwood W, Zelterman D, Homer R, Liu Z, Kaech S, Politi K.

J Immunother Cancer. 2019 Jul 10;7(1):172. doi: 10.1186/s40425-019-0643-8.

8.

A functional subset of CD8+ T cells during chronic exhaustion is defined by SIRPα expression.

Myers LM, Tal MC, Torrez Dulgeroff LB, Carmody AB, Messer RJ, Gulati G, Yiu YY, Staron MM, Angel CL, Sinha R, Markovic M, Pham EA, Fram B, Ahmed A, Newman AM, Glenn JS, Davis MM, Kaech SM, Weissman IL, Hasenkrug KJ.

Nat Commun. 2019 Feb 15;10(1):794. doi: 10.1038/s41467-019-08637-9.

9.

Differential Roles of IL-2 Signaling in Developing versus Mature Tregs.

Fan MY, Low JS, Tanimine N, Finn KK, Priyadharshini B, Germana SK, Kaech SM, Turka LA.

Cell Rep. 2018 Oct 30;25(5):1204-1213.e4. doi: 10.1016/j.celrep.2018.10.002.

10.

T-bet in Tfh cells: Now you see me, now you don't.

Kaech SM.

J Exp Med. 2018 Nov 5;215(11):2697-2698. doi: 10.1084/jem.20181878. Epub 2018 Oct 18.

11.

Active mTORC2 Signaling in Naive T Cells Suppresses Bone Marrow Homing by Inhibiting CXCR4 Expression.

Arojo OA, Ouyang X, Liu D, Meng T, Kaech SM, Pereira JP, Su B.

J Immunol. 2018 Aug 1;201(3):908-915. doi: 10.4049/jimmunol.1800529. Epub 2018 Jun 22.

12.

Metformin exerts antitumor activity via induction of multiple death pathways in tumor cells and activation of a protective immune response.

Pereira FV, Melo ACL, Low JS, de Castro ÍA, Braga TT, Almeida DC, Batista de Lima AGU, Hiyane MI, Correa-Costa M, Andrade-Oliveira V, Origassa CST, Pereira RM, Kaech SM, Rodrigues EG, Câmara NOS.

Oncotarget. 2018 May 25;9(40):25808-25825. doi: 10.18632/oncotarget.25380. eCollection 2018 May 25.

13.

KLRG1+ Effector CD8+ T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity.

Herndler-Brandstetter D, Ishigame H, Shinnakasu R, Plajer V, Stecher C, Zhao J, Lietzenmayer M, Kroehling L, Takumi A, Kometani K, Inoue T, Kluger Y, Kaech SM, Kurosaki T, Okada T, Flavell RA.

Immunity. 2018 Apr 17;48(4):716-729.e8. doi: 10.1016/j.immuni.2018.03.015. Epub 2018 Apr 3.

14.

Clinical Features and Management of Acquired Resistance to PD-1 Axis Inhibitors in 26 Patients With Advanced Non-Small Cell Lung Cancer.

Gettinger SN, Wurtz A, Goldberg SB, Rimm D, Schalper K, Kaech S, Kavathas P, Chiang A, Lilenbaum R, Zelterman D, Politi K, Herbst RS.

J Thorac Oncol. 2018 Jun;13(6):831-839. doi: 10.1016/j.jtho.2018.03.008. Epub 2018 Mar 22.

15.

ZEB1, ZEB2, and the miR-200 family form a counterregulatory network to regulate CD8+ T cell fates.

Guan T, Dominguez CX, Amezquita RA, Laidlaw BJ, Cheng J, Henao-Mejia J, Williams A, Flavell RA, Lu J, Kaech SM.

J Exp Med. 2018 Apr 2;215(4):1153-1168. doi: 10.1084/jem.20171352. Epub 2018 Feb 15.

16.

Correction: STAT4 and T-bet control follicular helper T cell development in viral infections.

Weinstein JS, Laidlaw BJ, Lu Y, Wang JK, Schulz VP, Li N, Herman EI, Kaech SM, Gallagher PG, Craft J.

J Exp Med. 2018 Mar 5;215(3):999. doi: 10.1084/jem.2017045702062018c. Epub 2018 Feb 13. No abstract available.

17.

Myeloid-targeted immunotherapies act in synergy to induce inflammation and antitumor immunity.

Perry CJ, Muñoz-Rojas AR, Meeth KM, Kellman LN, Amezquita RA, Thakral D, Du VY, Wang JX, Damsky W, Kuhlmann AL, Sher JW, Bosenberg M, Miller-Jensen K, Kaech SM.

J Exp Med. 2018 Mar 5;215(3):877-893. doi: 10.1084/jem.20171435. Epub 2018 Feb 7.

18.

Trials and Tribble-ations of tissue TRM cells.

Low JS, Kaech SM.

Nat Immunol. 2018 Feb;19(2):102-103. doi: 10.1038/s41590-017-0031-9. No abstract available.

19.

STAT4 and T-bet control follicular helper T cell development in viral infections.

Weinstein JS, Laidlaw BJ, Lu Y, Wang JK, Schulz VP, Li N, Herman EI, Kaech SM, Gallagher PG, Craft J.

J Exp Med. 2018 Jan 2;215(1):337-355. doi: 10.1084/jem.20170457. Epub 2017 Dec 6. Erratum in: J Exp Med. 2018 Feb 13;:.

20.

Interleukin-10 from CD4+ follicular regulatory T cells promotes the germinal center response.

Laidlaw BJ, Lu Y, Amezquita RA, Weinstein JS, Vander Heiden JA, Gupta NT, Kleinstein SH, Kaech SM, Craft J.

Sci Immunol. 2017 Oct 20;2(16). pii: eaan4767. doi: 10.1126/sciimmunol.aan4767.

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