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Items: 1 to 20 of 118


Intraoperative magnesium administration does not improve neurocognitive function after cardiac surgery.

Mathew JP, White WD, Schinderle DB, Podgoreanu MV, Berger M, Milano CA, Laskowitz DT, Stafford-Smith M, Blumenthal JA, Newman MF; Neurologic Outcome Research Group (NORG) of The Duke Heart Center..

Stroke. 2013 Dec;44(12):3407-13. doi: 10.1161/STROKEAHA.113.002703. Epub 2013 Oct 8.


Inhibition of protein misfolding/aggregation using polyglutamine binding peptide QBP1 as a therapy for the polyglutamine diseases.

Popiel HA, Takeuchi T, Burke JR, Strittmatter WJ, Toda T, Wada K, Nagai Y.

Neurotherapeutics. 2013 Jul;10(3):440-6. doi: 10.1007/s13311-013-0184-7. Review.


Bathing the brain.

Strittmatter WJ.

J Clin Invest. 2013 Mar;123(3):1013-5. doi: 10.1172/JCI68241. Epub 2013 Feb 22.


Predictors of cognitive recovery after cardiac surgery.

Fontes MT, Swift RC, Phillips-Bute B, Podgoreanu MV, Stafford-Smith M, Newman MF, Mathew JP; Neurologic Outcome Research Group of the Duke Heart Center..

Anesth Analg. 2013 Feb;116(2):435-42. doi: 10.1213/ANE.0b013e318273f37e. Epub 2013 Jan 9.


Alzheimer’s disease: the new promise.

Strittmatter WJ.

J Clin Invest. 2012 Apr;122(4):1191. No abstract available.


Medicine. Old drug, new hope for Alzheimer's disease.

Strittmatter WJ.

Science. 2012 Mar 23;335(6075):1447-8. doi: 10.1126/science.1220725. No abstract available.


The Aggregation Inhibitor Peptide QBP1 as a Therapeutic Molecule for the Polyglutamine Neurodegenerative Diseases.

Popiel HA, Burke JR, Strittmatter WJ, Oishi S, Fujii N, Takeuchi T, Toda T, Wada K, Nagai Y.

J Amino Acids. 2011;2011:265084. doi: 10.4061/2011/265084. Epub 2011 Jun 30.


Utility of a simple algorithm to grade diastolic dysfunction and predict outcome after coronary artery bypass graft surgery.

Swaminathan M, Nicoara A, Phillips-Bute BG, Aeschlimann N, Milano CA, Mackensen GB, Podgoreanu MV, Velazquez EJ, Stafford-Smith M, Mathew JP; Cardiothoracic Anesthesia Research Endeavors (CARE) Group..

Ann Thorac Surg. 2011 Jun;91(6):1844-50. doi: 10.1016/j.athoracsur.2011.02.008. Epub 2011 Apr 14.


Cognitive function after major noncardiac surgery, apolipoprotein E4 genotype, and biomarkers of brain injury.

McDonagh DL, Mathew JP, White WD, Phillips-Bute B, Laskowitz DT, Podgoreanu MV, Newman MF; Neurologic Outcome Research Group..

Anesthesiology. 2010 Apr;112(4):852-9. doi: 10.1097/ALN.0b013e3181d31fd7.


Genome-wide scan of copy number variation in late-onset Alzheimer's disease.

Heinzen EL, Need AC, Hayden KM, Chiba-Falek O, Roses AD, Strittmatter WJ, Burke JR, Hulette CM, Welsh-Bohmer KA, Goldstein DB.

J Alzheimers Dis. 2010;19(1):69-77. doi: 10.3233/JAD-2010-1212.


A genome-wide investigation of SNPs and CNVs in schizophrenia.

Need AC, Ge D, Weale ME, Maia J, Feng S, Heinzen EL, Shianna KV, Yoon W, Kasperaviciūte D, Gennarelli M, Strittmatter WJ, Bonvicini C, Rossi G, Jayathilake K, Cola PA, McEvoy JP, Keefe RS, Fisher EM, St Jean PL, Giegling I, Hartmann AM, Möller HJ, Ruppert A, Fraser G, Crombie C, Middleton LT, St Clair D, Roses AD, Muglia P, Francks C, Rujescu D, Meltzer HY, Goldstein DB.

PLoS Genet. 2009 Feb;5(2):e1000373. doi: 10.1371/journal.pgen.1000373. Epub 2009 Feb 6. Erratum in: PLoS Genet. 2009 Mar;5(3). doi: 10.1371/annotation/e0196ebb-de40-453f-8f8c-791b126618da.


Randomized, double-blinded, placebo controlled study of neuroprotection with lidocaine in cardiac surgery.

Mathew JP, Mackensen GB, Phillips-Bute B, Grocott HP, Glower DD, Laskowitz DT, Blumenthal JA, Newman MF; Neurologic Outcome Research Group (NORG) of the Duke Heart Center..

Stroke. 2009 Mar;40(3):880-7. doi: 10.1161/STROKEAHA.108.531236. Epub 2009 Jan 22.


Identification of chemical inhibitors to human tissue transglutaminase by screening existing drug libraries.

Lai TS, Liu Y, Tucker T, Daniel KR, Sane DC, Toone E, Burke JR, Strittmatter WJ, Greenberg CS.

Chem Biol. 2008 Sep 22;15(9):969-78. doi: 10.1016/j.chembiol.2008.07.015.


Apolipoprotein E genotype as a determinant of survival in chronic lymphocytic leukemia.

Weinberg JB, Volkheimer AD, Mihovilovic M, Jiang N, Chen Y, Bond K, Moore JO, Gockerman JP, Diehl LF, de Castro CM, Rizzieri DA, Levesque MC, Dekroon R, Strittmatter WJ.

Leukemia. 2008 Dec;22(12):2184-92. doi: 10.1038/leu.2008.241. Epub 2008 Sep 11.


Optimization of a polyglutamine aggregation inhibitor peptide (QBP1) using a thioflavin T fluorescence assay.

Hamuro L, Zhang G, Tucker TJ, Self C, Strittmatter WJ, Burke JR.

Assay Drug Dev Technol. 2007 Oct;5(5):629-36.


High-fat/high-cholesterol diet promotes a S1P receptor-mediated antiapoptotic activity for VLDL.

Mihovilovic M, Robinette JB, DeKroon RM, Sullivan PM, Strittmatter WJ.

J Lipid Res. 2007 Apr;48(4):806-15. Epub 2007 Jan 30.


Mortalin is regulated by APOE in hippocampus of AD patients and by human APOE in TR mice.

Osorio C, Sullivan PM, He DN, Mace BE, Ervin JF, Strittmatter WJ, Alzate O.

Neurobiol Aging. 2007 Dec;28(12):1853-62. Epub 2006 Oct 16.


Phage display screening for peptides that inhibit polyglutamine aggregation.

Kenan DJ, Strittmatter WJ, Burke JR.

Methods Enzymol. 2006;413:253-73.


APOE4-VLDL inhibits the HDL-activated phosphatidylinositol 3-kinase/Akt Pathway via the phosphoinositol phosphatase SHIP2.

DeKroon R, Robinette JB, Hjelmeland AB, Wiggins E, Blackwell M, Mihovilovic M, Fujii M, York J, Hart J, Kontos C, Rich J, Strittmatter WJ.

Circ Res. 2006 Oct 13;99(8):829-36. Epub 2006 Sep 14.


Polyglutamine expansion inhibits respiration by increasing reactive oxygen species in isolated mitochondria.

Puranam KL, Wu G, Strittmatter WJ, Burke JR.

Biochem Biophys Res Commun. 2006 Mar 10;341(2):607-13. Epub 2006 Jan 13.


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