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Items: 1 to 20 of 226

1.

Extracellular Phosphorylation of TIMP-2 by Secreted c-Src Tyrosine Kinase Controls MMP-2 Activity.

Sánchez-Pozo J, Baker-Williams AJ, Woodford MR, Bullard R, Wei B, Mollapour M, Stetler-Stevenson WG, Bratslavsky G, Bourboulia D.

iScience. 2018 Mar 23;1:87-96. doi: 10.1016/j.isci.2018.02.004. Epub 2018 Mar 23.

2.

Macromolecule-Network Electrostatics Controlling Delivery of the Biotherapeutic Cell Modulator TIMP-2.

Yamada Y, Chowdhury A, Schneider JP, Stetler-Stevenson WG.

Biomacromolecules. 2018 Apr 9;19(4):1285-1293. doi: 10.1021/acs.biomac.8b00107. Epub 2018 Mar 19.

3.

Tissue Inhibitor of Metalloprotease-2 (TIMP-2): Bioprocess Development, Physicochemical, Biochemical, and Biological Characterization of Highly Expressed Recombinant Protein.

Chowdhury A, Brinson R, Wei B, Stetler-Stevenson WG.

Biochemistry. 2017 Dec 12;56(49):6423-6433. doi: 10.1021/acs.biochem.7b00700. Epub 2017 Nov 28.

4.

Mps1 Mediated Phosphorylation of Hsp90 Confers Renal Cell Carcinoma Sensitivity and Selectivity to Hsp90 Inhibitors.

Woodford MR, Truman AW, Dunn DM, Jensen SM, Cotran R, Bullard R, Abouelleil M, Beebe K, Wolfgeher D, Wierzbicki S, Post DE, Caza T, Tsutsumi S, Panaretou B, Kron SJ, Trepel JB, Landas S, Prodromou C, Shapiro O, Stetler-Stevenson WG, Bourboulia D, Neckers L, Bratslavsky G, Mollapour M.

Cell Rep. 2016 Feb 2;14(4):872-884. doi: 10.1016/j.celrep.2015.12.084. Epub 2016 Jan 21.

5.

The tumor microenvironment: the connective tissue/tumor cell/host organ system that modulates tumor progression.

Stetler-Stevenson WG.

Connect Tissue Res. 2015;56(5):343-4. doi: 10.3109/03008207.2015.1086622. No abstract available.

6.

c-Abl Mediated Tyrosine Phosphorylation of Aha1 Activates Its Co-chaperone Function in Cancer Cells.

Dunn DM, Woodford MR, Truman AW, Jensen SM, Schulman J, Caza T, Remillard TC, Loiselle D, Wolfgeher D, Blagg BS, Franco L, Haystead TA, Daturpalli S, Mayer MP, Trepel JB, Morgan RM, Prodromou C, Kron SJ, Panaretou B, Stetler-Stevenson WG, Landas SK, Neckers L, Bratslavsky G, Bourboulia D, Mollapour M.

Cell Rep. 2015 Aug 11;12(6):1006-18. doi: 10.1016/j.celrep.2015.07.004. Epub 2015 Jul 30.

7.

Anti-inflammatory and antioxidant properties of Piper species: a perspective from screening to molecular mechanisms.

Kumar S, Malhotra S, Prasad AK, Van der Eycken EV, Bracke ME, Stetler-Stevenson WG, Parmar VS, Ghosh B.

Curr Top Med Chem. 2015;15(9):886-93. Review.

8.

Human cardiac fibroblast extracellular matrix remodeling: dual effects of tissue inhibitor of metalloproteinase-2.

Ngu JM, Teng G, Meijndert HC, Mewhort HE, Turnbull JD, Stetler-Stevenson WG, Fedak PW.

Cardiovasc Pathol. 2014 Nov-Dec;23(6):335-43. doi: 10.1016/j.carpath.2014.06.003. Epub 2014 Jun 21.

9.

Dietary intake of a plant phospholipid/lipid conjugate reduces lung cancer growth and tumor angiogenesis.

Shuman Moss LA, Jensen-Taubman S, Rubinstein D, Viole G, Stetler-Stevenson WG.

Carcinogenesis. 2014 Jul;35(7):1556-63. doi: 10.1093/carcin/bgu039. Epub 2014 Feb 7.

10.

Asymmetric Hsp90 N domain SUMOylation recruits Aha1 and ATP-competitive inhibitors.

Mollapour M, Bourboulia D, Beebe K, Woodford MR, Polier S, Hoang A, Chelluri R, Li Y, Guo A, Lee MJ, Fotooh-Abadi E, Khan S, Prince T, Miyajima N, Yoshida S, Tsutsumi S, Xu W, Panaretou B, Stetler-Stevenson WG, Bratslavsky G, Trepel JB, Prodromou C, Neckers L.

Mol Cell. 2014 Jan 23;53(2):317-29. doi: 10.1016/j.molcel.2013.12.007.

11.

Normalization of the tumor microenvironment: evidence for tissue inhibitor of metalloproteinase-2 as a cancer therapeutic.

Stetler-Stevenson WG, Gavil NV.

Connect Tissue Res. 2014 Jan-Feb;55(1):13-9. doi: 10.3109/03008207.2013.867339. Review.

12.

Molecular mechanisms of tissue inhibitor of metalloproteinase 2 in the tumor microenvironment.

Remillard TC, Bratslavsky G, Jensen-Taubman S, Stetler-Stevenson WG, Bourboulia D.

Mol Cell Ther. 2014 Jun 3;2:17. doi: 10.1186/2052-8426-2-17. eCollection 2014. Review.

13.

Influence of Stromal Components on Lung Cancer Carcinogenesis.

Shuman Moss LA, Stetler-Stevenson WG.

J Carcinog Mutagen. 2013 Jun 25;13(8). doi: 10.4172/2157-2518.S13-008.

14.

SCNH2 is a novel apelinergic family member acting as a potent mitogenic and chemotactic factor for both endothelial and epithelial cells.

Fang C, Avis I, Bianco C, Held N, Morris J, Ylaya K, Hewitt SM, Aplin AC, Nicosia RF, Fung LA, Lewis JD, Stetler-Stevenson WG, Salomon DS, Cuttitta F.

Open J Clin Diagn. 2013 Jun;3(2):37-51.

15.

Tissue inhibitor of metalloproteinase 1 is preferentially expressed in Th1 and Th17 T-helper cell subsets and is a direct STAT target gene.

Adamson A, Ghoreschi K, Rittler M, Chen Q, Sun HW, Vahedi G, Kanno Y, Stetler-Stevenson WG, O'Shea JJ, Laurence A.

PLoS One. 2013;8(3):e59367. doi: 10.1371/journal.pone.0059367. Epub 2013 Mar 26.

16.

An endogenous inhibitor of angiogenesis inversely correlates with side population phenotype and function in human lung cancer cells.

Han H, Bourboulia D, Jensen-Taubman S, Isaac B, Wei B, Stetler-Stevenson WG.

Oncogene. 2014 Feb 27;33(9):1198-206. doi: 10.1038/onc.2013.61. Epub 2013 Mar 11.

17.

TIMP-2 modulates cancer cell transcriptional profile and enhances E-cadherin/beta-catenin complex expression in A549 lung cancer cells.

Bourboulia D, Han H, Jensen-Taubman S, Gavil N, Isaac B, Wei B, Neckers L, Stetler-Stevenson WG.

Oncotarget. 2013 Jan;4(1):166-76.

18.

Antagonism of VEGF-A-induced increase in vascular permeability by an integrin α3β1-Shp-1-cAMP/PKA pathway.

Kim SH, Cho YR, Kim HJ, Oh JS, Ahn EK, Ko HJ, Hwang BJ, Lee SJ, Cho Y, Kim YK, Stetler-Stevenson WG, Seo DW.

Blood. 2012 Dec 6;120(24):4892-902. doi: 10.1182/blood-2012-05-428243. Epub 2012 Oct 16.

19.

Matrix metalloproteinases: changing roles in tumor progression and metastasis.

Shuman Moss LA, Jensen-Taubman S, Stetler-Stevenson WG.

Am J Pathol. 2012 Dec;181(6):1895-9. doi: 10.1016/j.ajpath.2012.08.044. Epub 2012 Oct 12. Review.

20.

Combined inhibition of Wee1 and Hsp90 activates intrinsic apoptosis in cancer cells.

Iwai A, Bourboulia D, Mollapour M, Jensen-Taubman S, Lee S, Donnelly AC, Yoshida S, Miyajima N, Tsutsumi S, Smith AK, Sun D, Wu X, Blagg BS, Trepel JB, Stetler-Stevenson WG, Neckers L.

Cell Cycle. 2012 Oct 1;11(19):3649-55. doi: 10.4161/cc.21926. Epub 2012 Aug 30.

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