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Items: 1 to 20 of 99

1.

Pretangle pathology within cholinergic nucleus basalis neurons coincides with neurotrophic and neurotransmitter receptor gene dysregulation during the progression of Alzheimer's disease.

Tiernan CT, Ginsberg SD, He B, Ward SM, Guillozet-Bongaarts AL, Kanaan NM, Mufson EJ, Counts SE.

Neurobiol Dis. 2018 May 31;117:125-136. doi: 10.1016/j.nbd.2018.05.021. [Epub ahead of print]

PMID:
29859871
2.

CA1 pyramidal neuron gene expression mosaics in the Ts65Dn murine model of Down syndrome and Alzheimer's disease following maternal choline supplementation.

Alldred MJ, Chao HM, Lee SH, Beilin J, Powers BE, Petkova E, Strupp BJ, Ginsberg SD.

Hippocampus. 2018 Apr;28(4):251-268. doi: 10.1002/hipo.22832. Epub 2018 Feb 12.

PMID:
29394516
3.

Expression profiling suggests microglial impairment in human immunodeficiency virus neuropathogenesis.

Ginsberg SD, Alldred MJ, Gunnam SM, Schiroli C, Lee SH, Morgello S, Fischer T.

Ann Neurol. 2018 Feb;83(2):406-417. doi: 10.1002/ana.25160. Epub 2018 Feb 10.

PMID:
29369399
4.

Gene Profiling of Nucleus Basalis Tau Containing Neurons in Chronic Traumatic Encephalopathy: A Chronic Effects of Neurotrauma Consortium Study.

Mufson EJ, He B, Ginsberg SD, Carper BA, Bieler GS, Crawford F, Alvarez VE, Huber BR, Stein TD, McKee AC, Perez SE.

J Neurotrauma. 2018 Jun 1;35(11):1260-1271. doi: 10.1089/neu.2017.5368. Epub 2018 Apr 5.

PMID:
29338612
5.

The Stress-Induced Transcription Factor NR4A1 Adjusts Mitochondrial Function and Synapse Number in Prefrontal Cortex.

Jeanneteau F, Barrère C, Vos M, De Vries CJM, Rouillard C, Levesque D, Dromard Y, Moisan MP, Duric V, Franklin TC, Duman RS, Lewis DA, Ginsberg SD, Arango-Lievano M.

J Neurosci. 2018 Feb 7;38(6):1335-1350. doi: 10.1523/JNEUROSCI.2793-17.2017. Epub 2018 Jan 2.

PMID:
29295823
6.

Selective decline of neurotrophin and neurotrophin receptor genes within CA1 pyramidal neurons and hippocampus proper: Correlation with cognitive performance and neuropathology in mild cognitive impairment and Alzheimer's disease.

Ginsberg SD, Malek-Ahmadi MH, Alldred MJ, Che S, Elarova I, Chen Y, Jeanneteau F, Kranz TM, Chao MV, Counts SE, Mufson EJ.

Hippocampus. 2017 Sep 9. doi: 10.1002/hipo.22802. [Epub ahead of print]

PMID:
28888073
7.

Enhanced exosome secretion in Down syndrome brain - a protective mechanism to alleviate neuronal endosomal abnormalities.

Gauthier SA, Pérez-González R, Sharma A, Huang FK, Alldred MJ, Pawlik M, Kaur G, Ginsberg SD, Neubert TA, Levy E.

Acta Neuropathol Commun. 2017 Aug 29;5(1):65. doi: 10.1186/s40478-017-0466-0.

8.

Locus coeruleus cellular and molecular pathology during the progression of Alzheimer's disease.

Kelly SC, He B, Perez SE, Ginsberg SD, Mufson EJ, Counts SE.

Acta Neuropathol Commun. 2017 Jan 21;5(1):8. doi: 10.1186/s40478-017-0411-2.

9.

Deletion of Neurotrophin Signaling through the Glucocorticoid Receptor Pathway Causes Tau Neuropathology.

Arango-Lievano M, Peguet C, Catteau M, Parmentier ML, Wu S, Chao MV, Ginsberg SD, Jeanneteau F.

Sci Rep. 2016 Nov 16;6:37231. doi: 10.1038/srep37231.

10.

Maternal choline supplementation in a mouse model of Down syndrome: Effects on attention and nucleus basalis/substantia innominata neuron morphology in adult offspring.

Powers BE, Kelley CM, Velazquez R, Ash JA, Strawderman MS, Alldred MJ, Ginsberg SD, Mufson EJ, Strupp BJ.

Neuroscience. 2017 Jan 6;340:501-514. doi: 10.1016/j.neuroscience.2016.11.001. Epub 2016 Nov 10.

11.

Autophagy flux in CA1 neurons of Alzheimer hippocampus: Increased induction overburdens failing lysosomes to propel neuritic dystrophy.

Bordi M, Berg MJ, Mohan PS, Peterhoff CM, Alldred MJ, Che S, Ginsberg SD, Nixon RA.

Autophagy. 2016 Dec;12(12):2467-2483. Epub 2016 Nov 4.

12.

Tau downregulates BDNF expression in animal and cellular models of Alzheimer's disease.

Rosa E, Mahendram S, Ke YD, Ittner LM, Ginsberg SD, Fahnestock M.

Neurobiol Aging. 2016 Dec;48:135-142. doi: 10.1016/j.neurobiolaging.2016.08.020. Epub 2016 Aug 31.

13.

Increased Expression of Readthrough Acetylcholinesterase Variants in the Brains of Alzheimer's Disease Patients.

Campanari ML, Navarrete F, Ginsberg SD, Manzanares J, Sáez-Valero J, García-Ayllón MS.

J Alzheimers Dis. 2016 May 30;53(3):831-41. doi: 10.3233/JAD-160220.

14.

Molecular and cellular pathophysiology of preclinical Alzheimer's disease.

Mufson EJ, Ikonomovic MD, Counts SE, Perez SE, Malek-Ahmadi M, Scheff SW, Ginsberg SD.

Behav Brain Res. 2016 Sep 15;311:54-69. doi: 10.1016/j.bbr.2016.05.030. Epub 2016 May 13. Review.

15.

Protein homeostasis gene dysregulation in pretangle-bearing nucleus basalis neurons during the progression of Alzheimer's disease.

Tiernan CT, Ginsberg SD, Guillozet-Bongaarts AL, Ward SM, He B, Kanaan NM, Mufson EJ, Binder LI, Counts SE.

Neurobiol Aging. 2016 Jun;42:80-90. doi: 10.1016/j.neurobiolaging.2016.02.031. Epub 2016 Mar 8.

16.

Brain-Wide Insulin Resistance, Tau Phosphorylation Changes, and Hippocampal Neprilysin and Amyloid-β Alterations in a Monkey Model of Type 1 Diabetes.

Morales-Corraliza J, Wong H, Mazzella MJ, Che S, Lee SH, Petkova E, Wagner JD, Hemby SE, Ginsberg SD, Mathews PM.

J Neurosci. 2016 Apr 13;36(15):4248-58. doi: 10.1523/JNEUROSCI.4640-14.2016.

17.

Partial BACE1 reduction in a Down syndrome mouse model blocks Alzheimer-related endosomal anomalies and cholinergic neurodegeneration: role of APP-CTF.

Jiang Y, Rigoglioso A, Peterhoff CM, Pawlik M, Sato Y, Bleiwas C, Stavrides P, Smiley JF, Ginsberg SD, Mathews PM, Levy E, Nixon RA.

Neurobiol Aging. 2016 Mar;39:90-8. doi: 10.1016/j.neurobiolaging.2015.11.013. Epub 2015 Dec 2.

18.

Attentional function and basal forebrain cholinergic neuron morphology during aging in the Ts65Dn mouse model of Down syndrome.

Powers BE, Velazquez R, Kelley CM, Ash JA, Strawderman MS, Alldred MJ, Ginsberg SD, Mufson EJ, Strupp BJ.

Brain Struct Funct. 2016 Dec;221(9):4337-4352. Epub 2015 Dec 30.

19.

Neuronal ceroid lipofuscinosis with DNAJC5/CSPα mutation has PPT1 pathology and exhibit aberrant protein palmitoylation.

Henderson MX, Wirak GS, Zhang YQ, Dai F, Ginsberg SD, Dolzhanskaya N, Staropoli JF, Nijssen PC, Lam TT, Roth AF, Davis NG, Dawson G, Velinov M, Chandra SS.

Acta Neuropathol. 2016 Apr;131(4):621-37. doi: 10.1007/s00401-015-1512-2. Epub 2015 Dec 10.

20.

Maternal Choline Supplementation: A Potential Prenatal Treatment for Down Syndrome and Alzheimer's Disease.

Strupp BJ, Powers BE, Velazquez R, Ash JA, Kelley CM, Alldred MJ, Strawderman M, Caudill MA, Mufson EJ, Ginsberg SD.

Curr Alzheimer Res. 2016;13(1):97-106.

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