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PLoS Comput Biol. 2005 Sep;1(4):e42.

The human connectome: A structural description of the human brain.

Author information

1
Department of Psychology, Indiana University, Bloomington, Indiana, United States of America. osporns@indiana.edu

Abstract

The connection matrix of the human brain (the human "connectome") represents an indispensable foundation for basic and applied neurobiological research. However, the network of anatomical connections linking the neuronal elements of the human brain is still largely unknown. While some databases or collations of large-scale anatomical connection patterns exist for other mammalian species, there is currently no connection matrix of the human brain, nor is there a coordinated research effort to collect, archive, and disseminate this important information. We propose a research strategy to achieve this goal, and discuss its potential impact.

PMID:
16201007
PMCID:
PMC1239902
DOI:
10.1371/journal.pcbi.0010042
[Indexed for MEDLINE]
Free PMC Article

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