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Items: 1 to 20 of 55

1.

Bioorthogonal Metabolic Labeling of Nascent RNA in Neurons Improves the Sensitivity of Transcriptome-Wide Profiling.

Zajaczkowski EL, Zhao QY, Zhang ZH, Li X, Wei W, Marshall PR, Leighton LJ, Nainar S, Feng C, Spitale RC, Bredy TW.

ACS Chem Neurosci. 2018 Jul 18;9(7):1858-1865. doi: 10.1021/acschemneuro.8b00197. Epub 2018 Jun 15.

PMID:
29874042
2.

Spatially Restricting Bioorthogonal Nucleoside Biosynthesis Enables Selective Metabolic Labeling of the Mitochondrial Transcriptome.

Nguyen K, Aggarwal MB, Feng C, Balderrama G, Fazio M, Mortazavi A, Spitale RC.

ACS Chem Biol. 2018 Jun 15;13(6):1474-1479. doi: 10.1021/acschembio.8b00262. Epub 2018 May 17.

PMID:
29756767
3.

Improved Analysis of RNA Localization by Spatially Restricted Oxidation of RNA-Protein Complexes.

Li Y, Aggarwal MB, Ke K, Nguyen K, Spitale RC.

Biochemistry. 2018 Mar 13;57(10):1577-1581. doi: 10.1021/acs.biochem.8b00053. Epub 2018 Feb 27.

PMID:
29474061
4.

Light-activated chemical probing of nucleobase solvent accessibility inside cells.

Feng C, Chan D, Joseph J, Muuronen M, Coldren WH, Dai N, Corrêa IR Jr, Furche F, Hadad CM, Spitale RC.

Nat Chem Biol. 2018 Feb 14;14(3):325. doi: 10.1038/nchembio0318-325.

PMID:
29443971
5.

Facile synthesis and evaluation of a dual-functioning furoyl probe for in-cell SHAPE.

Chan D, Beasley S, Zhen Y, Spitale RC.

Bioorg Med Chem Lett. 2018 Feb 15;28(4):601-605. doi: 10.1016/j.bmcl.2018.01.042. Epub 2018 Feb 1.

PMID:
29398542
6.

Light-activated chemical probing of nucleobase solvent accessibility inside cells.

Feng C, Chan D, Joseph J, Muuronen M, Coldren WH, Dai N, Corrêa IR Jr, Furche F, Hadad CM, Spitale RC.

Nat Chem Biol. 2018 Mar;14(3):276-283. doi: 10.1038/nchembio.2548. Epub 2018 Jan 15. Erratum in: Nat Chem Biol. 2018 Feb 14;14 (3):325.

PMID:
29334380
7.

Defining Functional Structured RNA inside Living Cells.

Chan D, Spitale RC.

Biochemistry. 2017 Nov 7;56(44):5847-5848. doi: 10.1021/acs.biochem.7b00816. No abstract available.

PMID:
29064690
8.

Assaying RNA Localization in Situ with Spatially Restricted Nucleobase Oxidation.

Li Y, Aggarwal MB, Nguyen K, Ke K, Spitale RC.

ACS Chem Biol. 2017 Nov 17;12(11):2709-2714. doi: 10.1021/acschembio.7b00519. Epub 2017 Oct 9.

PMID:
28952711
9.

Experience-dependent neural plasticity, learning, and memory in the era of epitranscriptomics.

Leighton LJ, Ke K, Zajaczkowski EL, Edmunds J, Spitale RC, Bredy TW.

Genes Brain Behav. 2018 Mar;17(3):e12426. doi: 10.1111/gbb.12426. Epub 2017 Oct 20. Review.

PMID:
28926184
10.

Assaying RNA Structure Inside Living Cells with SHAPE.

Feng C, Chan D, Spitale RC.

Methods Mol Biol. 2017;1648:247-256. doi: 10.1007/978-1-4939-7204-3_18.

PMID:
28766302
11.

Multiplex Aptamer Discovery through Apta-Seq and Its Application to ATP Aptamers Derived from Human-Genomic SELEX.

Abdelsayed MM, Ho BT, Vu MMK, Polanco J, Spitale RC, Lupták A.

ACS Chem Biol. 2017 Aug 18;12(8):2149-2156. doi: 10.1021/acschembio.7b00001. Epub 2017 Jul 11.

12.

EC-tagging allows cell type-specific RNA analysis.

Hida N, Aboukilila MY, Burow DA, Paul R, Greenberg MM, Fazio M, Beasley S, Spitale RC, Cleary MD.

Nucleic Acids Res. 2017 Sep 6;45(15):e138. doi: 10.1093/nar/gkx551.

13.

Photo-controlled cell-specific metabolic labeling of RNA.

Feng C, Li Y, Spitale RC.

Org Biomol Chem. 2017 Jun 21;15(24):5117-5120. doi: 10.1039/c7ob01009e.

PMID:
28569333
14.

Temporal Labeling of Nascent RNA Using Photoclick Chemistry in Live Cells.

Nainar S, Kubota M, McNitt C, Tran C, Popik VV, Spitale RC.

J Am Chem Soc. 2017 Jun 21;139(24):8090-8093. doi: 10.1021/jacs.7b03121. Epub 2017 Jun 8.

PMID:
28562039
15.

Initial in vitro functional characterization of serum exosomal microRNAs from patients with metastatic basal cell carcinoma.

Chang J, Tran DC, Zhu GA, Li R, Whitson R, Kim YH, Gupta A, Afshari A, Antes T, Spitale RC, Chang ALS.

Br J Dermatol. 2017 Nov;177(5):e187-e190. doi: 10.1111/bjd.15508. Epub 2017 Sep 26. No abstract available.

PMID:
28369780
16.

Measuring RNA structure transcriptome-wide with icSHAPE.

Chan D, Feng C, Spitale RC.

Methods. 2017 May 1;120:85-90. doi: 10.1016/j.ymeth.2017.02.010. Epub 2017 Mar 20. Review.

PMID:
28336307
17.

MotifMap-RNA: a genome-wide map of RBP binding sites.

Liu Y, Sun S, Bredy T, Wood M, Spitale RC, Baldi P.

Bioinformatics. 2017 Jul 1;33(13):2029-2031. doi: 10.1093/bioinformatics/btx087.

PMID:
28334276
18.

Comparative Analysis Reveals Furoyl in Vivo Selective Hydroxyl Acylation Analyzed by Primer Extension Reagents Form Stable Ribosyl Ester Adducts.

Chan D, Feng C, Zhen Y, Flynn RA, Spitale RC.

Biochemistry. 2017 Apr 4;56(13):1811-1814. doi: 10.1021/acs.biochem.7b00128. Epub 2017 Mar 21.

PMID:
28319368
19.

Cell-Selective Bioorthogonal Metabolic Labeling of RNA.

Nguyen K, Fazio M, Kubota M, Nainar S, Feng C, Li X, Atwood SX, Bredy TW, Spitale RC.

J Am Chem Soc. 2017 Feb 15;139(6):2148-2151. doi: 10.1021/jacs.6b11401. Epub 2017 Feb 7.

PMID:
28139910
20.

Novel Gene Expression Profile of Women with Intrinsic Skin Youthfulness by Whole Transcriptome Sequencing.

Xu J, Spitale RC, Guan L, Flynn RA, Torre EA, Li R, Raber I, Qu K, Kern D, Knaggs HE, Chang HY, Chang AL.

PLoS One. 2016 Nov 9;11(11):e0165913. doi: 10.1371/journal.pone.0165913. eCollection 2016.

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