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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 2
2006 1
2007 2
2008 10
2009 21
2010 28
2011 19
2012 22
2013 24
2014 15
2015 13
2016 15
2017 7
2018 13
2019 15
2020 17
2021 9
2022 12
2023 2
2024 3

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199 results

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Page 1
Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis.
Anastasiou D, Yu Y, Israelsen WJ, Jiang JK, Boxer MB, Hong BS, Tempel W, Dimov S, Shen M, Jha A, Yang H, Mattaini KR, Metallo CM, Fiske BP, Courtney KD, Malstrom S, Khan TM, Kung C, Skoumbourdis AP, Veith H, Southall N, Walsh MJ, Brimacombe KR, Leister W, Lunt SY, Johnson ZR, Yen KE, Kunii K, Davidson SM, Christofk HR, Austin CP, Inglese J, Harris MH, Asara JM, Stephanopoulos G, Salituro FG, Jin S, Dang L, Auld DS, Park HW, Cantley LC, Thomas CJ, Vander Heiden MG. Anastasiou D, et al. Among authors: southall n. Nat Chem Biol. 2012 Oct;8(10):839-47. doi: 10.1038/nchembio.1060. Nat Chem Biol. 2012. PMID: 22922757 Free PMC article.
Mannose receptor (CD206) activation in tumor-associated macrophages enhances adaptive and innate antitumor immune responses.
Jaynes JM, Sable R, Ronzetti M, Bautista W, Knotts Z, Abisoye-Ogunniyan A, Li D, Calvo R, Dashnyam M, Singh A, Guerin T, White J, Ravichandran S, Kumar P, Talsania K, Chen V, Ghebremedhin A, Karanam B, Bin Salam A, Amin R, Odzorig T, Aiken T, Nguyen V, Bian Y, Zarif JC, de Groot AE, Mehta M, Fan L, Hu X, Simeonov A, Pate N, Abu-Asab M, Ferrer M, Southall N, Ock CY, Zhao Y, Lopez H, Kozlov S, de Val N, Yates CC, Baljinnyam B, Marugan J, Rudloff U. Jaynes JM, et al. Among authors: southall n. Sci Transl Med. 2020 Feb 12;12(530):eaax6337. doi: 10.1126/scitranslmed.aax6337. Sci Transl Med. 2020. PMID: 32051227 Free PMC article.
Defining clinical outcome pathways.
Korn D, Thieme AJ, Alves VM, Yeakey M, Borba JVVB, Capuzzi SJ, Fecho K, Bizon C, Edwards SW, Chirkova R, Colvis CM, Southall NT, Austin CP, Muratov EN, Tropsha A. Korn D, et al. Among authors: southall nt. Drug Discov Today. 2022 Jun;27(6):1671-1678. doi: 10.1016/j.drudis.2022.02.008. Epub 2022 Feb 16. Drug Discov Today. 2022. PMID: 35182735 Review.
Deconstructing the Translational Tower of Babel.
Austin CP, Colvis CM, Southall NT. Austin CP, et al. Among authors: southall nt. Clin Transl Sci. 2019 Mar;12(2):85. doi: 10.1111/cts.12595. Epub 2018 Nov 9. Clin Transl Sci. 2019. PMID: 30412342 Free PMC article. No abstract available.
Advancing precision medicine with personalized drug screening.
Gorshkov K, Chen CZ, Marshall RE, Mihatov N, Choi Y, Nguyen DT, Southall N, Chen KG, Park JK, Zheng W. Gorshkov K, et al. Among authors: southall n. Drug Discov Today. 2019 Jan;24(1):272-278. doi: 10.1016/j.drudis.2018.08.010. Epub 2018 Aug 17. Drug Discov Today. 2019. PMID: 30125678 Free PMC article. Review.
The NCATS Pharmaceutical Collection: a 10-year update.
Huang R, Zhu H, Shinn P, Ngan D, Ye L, Thakur A, Grewal G, Zhao T, Southall N, Hall MD, Simeonov A, Austin CP. Huang R, et al. Among authors: southall n. Drug Discov Today. 2019 Dec;24(12):2341-2349. doi: 10.1016/j.drudis.2019.09.019. Epub 2019 Oct 1. Drug Discov Today. 2019. PMID: 31585169 Review.
Unexplored therapeutic opportunities in the human genome.
Oprea TI, Bologa CG, Brunak S, Campbell A, Gan GN, Gaulton A, Gomez SM, Guha R, Hersey A, Holmes J, Jadhav A, Jensen LJ, Johnson GL, Karlson A, Leach AR, Ma'ayan A, Malovannaya A, Mani S, Mathias SL, McManus MT, Meehan TF, von Mering C, Muthas D, Nguyen DT, Overington JP, Papadatos G, Qin J, Reich C, Roth BL, Schürer SC, Simeonov A, Sklar LA, Southall N, Tomita S, Tudose I, Ursu O, Vidovic D, Waller A, Westergaard D, Yang JJ, Zahoránszky-Köhalmi G. Oprea TI, et al. Among authors: southall n. Nat Rev Drug Discov. 2018 May;17(5):317-332. doi: 10.1038/nrd.2018.14. Epub 2018 Mar 23. Nat Rev Drug Discov. 2018. PMID: 29472638 Free PMC article. Review.
Progress toward a universal biomedical data translator.
Fecho K, Thessen AE, Baranzini SE, Bizon C, Hadlock JJ, Huang S, Roper RT, Southall N, Ta C, Watkins PB, Williams MD, Xu H, Byrd W, Dančík V, Duby MP, Dumontier M, Glusman G, Harris NL, Hinderer EW, Hyde G, Johs A, Su AI, Qin G, Zhu Q; Biomedical Data Translator Consortium. Fecho K, et al. Among authors: southall n. Clin Transl Sci. 2022 May 25;15(8):1838-47. doi: 10.1111/cts.13301. Online ahead of print. Clin Transl Sci. 2022. PMID: 35611543 Free PMC article. Review.
Clinical development times for innovative drugs.
Brown DG, Wobst HJ, Kapoor A, Kenna LA, Southall N. Brown DG, et al. Among authors: southall n. Nat Rev Drug Discov. 2022 Nov;21(11):793-794. doi: 10.1038/d41573-021-00190-9. Nat Rev Drug Discov. 2022. PMID: 34759309 Free PMC article.
Evaluating kratom alkaloids using PHASE.
Ellis CR, Racz R, Kruhlak NL, Kim MT, Zakharov AV, Southall N, Hawkins EG, Burkhart K, Strauss DG, Stavitskaya L. Ellis CR, et al. Among authors: southall n. PLoS One. 2020 Mar 3;15(3):e0229646. doi: 10.1371/journal.pone.0229646. eCollection 2020. PLoS One. 2020. PMID: 32126112 Free PMC article.
199 results