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Items: 1 to 20 of 42


JC polyomavirus (JCV) and monoclonal antibodies: friends or potential foes?

Diotti RA, Nakanishi A, Clementi N, Mancini N, Criscuolo E, Solforosi L, Clementi M.

Clin Dev Immunol. 2013;2013:967581. doi: 10.1155/2013/967581. Epub 2013 Jun 25. Review.


Lack of prion infectivity in fixed heart tissue from patients with Creutzfeldt-Jakob disease or amyloid heart disease.

Priola SA, Ward AE, McCall SA, Trifilo M, Choi YP, Solforosi L, Williamson RA, Cruite JT, Oldstone MB.

J Virol. 2013 Sep;87(17):9501-10. doi: 10.1128/JVI.00692-13. Epub 2013 Jun 19.


A closer look at prion strains: characterization and important implications.

Solforosi L, Milani M, Mancini N, Clementi M, Burioni R.

Prion. 2013 Mar-Apr;7(2):99-108. doi: 10.4161/pri.23490. Epub 2013 Jan 28. Review.


Neutralization interfering antibodies: a "novel" example of humoral immune dysfunction facilitating viral escape?

Nicasio M, Sautto G, Clementi N, Diotti RA, Criscuolo E, Castelli M, Solforosi L, Clementi M, Burioni R.

Viruses. 2012 Sep;4(9):1731-52. doi: 10.3390/v4091731. Epub 2012 Sep 24. Review.


Neutralization activity and kinetics of two broad-range human monoclonal IgG1 derived from recombinant Fab fragments and directed against Hepatitis C virus E2 glycoprotein.

Diotti RA, Sautto GA, Solforosi L, Mancini N, Clementi M, Burioni R.

New Microbiol. 2012 Oct;35(4):475-9. Epub 2012 Oct 1.


Phage display-based strategies for cloning and optimization of monoclonal antibodies directed against human pathogens.

Clementi N, Mancini N, Solforosi L, Castelli M, Clementi M, Burioni R.

Int J Mol Sci. 2012;13(7):8273-92. doi: 10.3390/ijms13078273. Epub 2012 Jul 4. Review.


Anti-hepatitis C virus E2 (HCV/E2) glycoprotein monoclonal antibodies and neutralization interference.

Sautto G, Mancini N, Diotti RA, Solforosi L, Clementi M, Burioni R.

Antiviral Res. 2012 Oct;96(1):82-9. doi: 10.1016/j.antiviral.2012.07.013. Epub 2012 Aug 7.


A phage display vector optimized for the generation of human antibody combinatorial libraries and the molecular cloning of monoclonal antibody fragments.

Solforosi L, Mancini N, Canducci F, Clementi N, Sautto GA, Diotti RA, Clementi M, Burioni R.

New Microbiol. 2012 Jul;35(3):289-94. Epub 2012 Jun 30.


HCV proteins and immunoglobulin variable gene (IgV) subfamilies in HCV-induced type II mixed cryoglobulinemia: a concurrent pathogenetic role.

Sautto G, Mancini N, Solforosi L, Diotti RA, Clementi M, Burioni R.

Clin Dev Immunol. 2012;2012:705013. doi: 10.1155/2012/705013. Epub 2012 May 29. Review.


A non-VH1-69 heterosubtypic neutralizing human monoclonal antibody protects mice against H1N1 and H5N1 viruses.

De Marco D, Clementi N, Mancini N, Solforosi L, Moreno GJ, Sun X, Tumpey TM, Gubareva LV, Mishin V, Clementi M, Burioni R.

PLoS One. 2012;7(4):e34415. doi: 10.1371/journal.pone.0034415. Epub 2012 Apr 4.


A human monoclonal antibody with neutralizing activity against highly divergent influenza subtypes.

Clementi N, De Marco D, Mancini N, Solforosi L, Moreno GJ, Gubareva LV, Mishin V, Di Pietro A, Vicenzi E, Siccardi AG, Clementi M, Burioni R.

PLoS One. 2011;6(12):e28001. doi: 10.1371/journal.pone.0028001. Epub 2011 Dec 5.


A potential role for monoclonal antibodies in prophylactic and therapeutic treatment of influenza.

Mancini N, Solforosi L, Clementi N, De Marco D, Clementi M, Burioni R.

Antiviral Res. 2011 Oct;92(1):15-26. doi: 10.1016/j.antiviral.2011.07.013. Epub 2011 Jul 21. Review.


Histidines in the octapeptide repeat of PrPC react with PrPSc at an acidic pH.

Cruite JT, Abalos GC, Bellon A, Solforosi L.

Biochemistry. 2011 Mar 15;50(10):1618-23. doi: 10.1021/bi1017683. Epub 2011 Feb 16.


Identifying key components of the PrPC-PrPSc replicative interface.

Abalos GC, Cruite JT, Bellon A, Hemmers S, Akagi J, Mastrianni JA, Williamson RA, Solforosi L.

J Biol Chem. 2008 Dec 5;283(49):34021-8. doi: 10.1074/jbc.M804475200. Epub 2008 Sep 30.


Scrapie-induced defects in learning and memory of transgenic mice expressing anchorless prion protein are associated with alterations in the gamma aminobutyric acid-ergic pathway.

Trifilo MJ, Sanchez-Alavez M, Solforosi L, Bernard-Trifilo J, Kunz S, McGavern D, Oldstone MB.

J Virol. 2008 Oct;82(20):9890-9. doi: 10.1128/JVI.00486-08. Epub 2008 Jul 30.


Non-infectious aggregates of the prion protein react with several PrPSc-directed antibodies.

Biasini E, Seegulam ME, Patti BN, Solforosi L, Medrano AZ, Christensen HM, Senatore A, Chiesa R, Williamson RA, Harris DA.

J Neurochem. 2008 Jun 1;105(6):2190-204. doi: 10.1111/j.1471-4159.2008.05306.x.


Toward molecular dissection of PrPC-PrPSc interactions.

Solforosi L, Bellon A, Schaller M, Cruite JT, Abalos GC, Williamson RA.

J Biol Chem. 2007 Mar 9;282(10):7465-71. Epub 2007 Jan 10.


Motif-grafted antibodies containing the replicative interface of cellular PrP are specific for PrPSc.

Moroncini G, Kanu N, Solforosi L, Abalos G, Telling GC, Head M, Ironside J, Brockes JP, Burton DR, Williamson RA.

Proc Natl Acad Sci U S A. 2004 Jul 13;101(28):10404-9. Epub 2004 Jul 6.


Cross-linking cellular prion protein triggers neuronal apoptosis in vivo.

Solforosi L, Criado JR, McGavern DB, Wirz S, Sánchez-Alavez M, Sugama S, DeGiorgio LA, Volpe BT, Wiseman E, Abalos G, Masliah E, Gilden D, Oldstone MB, Conti B, Williamson RA.

Science. 2004 Mar 5;303(5663):1514-6. Epub 2004 Jan 29.


Conformation of PrP(C) on the cell surface as probed by antibodies.

Leclerc E, Peretz D, Ball H, Solforosi L, Legname G, Safar J, Serban A, Prusiner SB, Burton DR, Williamson RA.

J Mol Biol. 2003 Feb 14;326(2):475-83.


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