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J Clin Endocrinol Metab. 2016 Apr;101(4):1414-21. doi: 10.1210/jc.2015-4017. Epub 2016 Feb 10.

Sodium Intake and Osteoporosis. Findings From the Women's Health Initiative.

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Department of Medicine, Division of Rheumatology (L.C., M.B.), Medical College of Georgia-Augusta University and Charlie Norwood Veterans Affairs Medical Center (L.C., M.B.), Augusta, GA 30912; Department of Preventive Medicine (K.C.J., F.T.), University of Tennessee Health Science Center, Memphis, Tennessee 38163; Division of Public Health Sciences (Y.H., M.P., L.T., R.P.), Fred Hutchinson Cancer Research Center, Seattle, Washington 98109; Department of Epidemiology (J.C.), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15261; David Geffen School of Medicine (C.C.), University of California, Los Angeles, Los Angeles, California 90095; Department of Medicine (M.S.L.), Harvard University, Brigham and Women's Hospital, Boston, Massachusetts 02115; Department of Epidemiology and Environmental Health (J.W.-W.), University at Buffalo, The State University of New York, Buffalo, New York 14214; and Division of Preventive and Behavioral Medicine (W.L.), University of Massachusetts Medical School, Worcester, Massachusetts 01655.


In this large, prospective, observational cohort study of postmenopausal women in the WHI, Cox proportional hazard regression models showed that sodium intake at or near recommended levels is not likely to impact bone metabolism.

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