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Year Number of Results
2010 5
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2017 1
2018 2
2023 1
2024 1

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Page 1
Chemical genetics of Plasmodium falciparum.
Guiguemde WA, Shelat AA, Bouck D, Duffy S, Crowther GJ, Davis PH, Smithson DC, Connelly M, Clark J, Zhu F, Jiménez-Díaz MB, Martinez MS, Wilson EB, Tripathi AK, Gut J, Sharlow ER, Bathurst I, El Mazouni F, Fowble JW, Forquer I, McGinley PL, Castro S, Angulo-Barturen I, Ferrer S, Rosenthal PJ, Derisi JL, Sullivan DJ, Lazo JS, Roos DS, Riscoe MK, Phillips MA, Rathod PK, Van Voorhis WC, Avery VM, Guy RK. Guiguemde WA, et al. Among authors: smithson dc. Nature. 2010 May 20;465(7296):311-5. doi: 10.1038/nature09099. Nature. 2010. PMID: 20485428 Free PMC article.
Cysteine modifiers suggest an allosteric inhibitory site on the CAL PDZ domain.
Zhao Y, Cushing PR, Smithson DC, Pellegrini M, Pletnev AA, Al-Ayyoubi S, Grassetti AV, Gerber SA, Guy RK, Madden DR. Zhao Y, et al. Among authors: smithson dc. Biosci Rep. 2018 Jul 6;38(4):BSR20180231. doi: 10.1042/BSR20180231. Print 2018 Aug 31. Biosci Rep. 2018. PMID: 29472314 Free PMC article.
Discovery of novel, orally bioavailable, antileishmanial compounds using phenotypic screening.
Ortiz D, Guiguemde WA, Hammill JT, Carrillo AK, Chen Y, Connelly M, Stalheim K, Elya C, Johnson A, Min J, Shelat A, Smithson DC, Yang L, Zhu F, Guy RK, Landfear SM. Ortiz D, et al. Among authors: smithson dc. PLoS Negl Trop Dis. 2017 Dec 29;11(12):e0006157. doi: 10.1371/journal.pntd.0006157. eCollection 2017 Dec. PLoS Negl Trop Dis. 2017. PMID: 29287089 Free PMC article.
Podophyllotoxin analogues active versus Trypanosoma brucei.
Uddin MJ, Smithson DC, Brown KM, Crews BC, Connelly M, Zhu F, Marnett LJ, Guy RK. Uddin MJ, et al. Among authors: smithson dc. Bioorg Med Chem Lett. 2010 Mar 1;20(5):1787-91. doi: 10.1016/j.bmcl.2010.01.009. Epub 2010 Jan 11. Bioorg Med Chem Lett. 2010. PMID: 20129783 Free PMC article.
13 results