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SLC15A4 mediates M1-prone metabolic shifts in macrophages and guards immune cells from metabolic stress.
Proc Natl Acad Sci U S A. 2021 Aug 17;118(33):e2100295118. doi: 10.1073/pnas.2100295118.
Proc Natl Acad Sci U S A. 2021.
PMID: 34385317
Free PMC article.
Type I interferon limits mast cell-mediated anaphylaxis by controlling secretory granule homeostasis.
Kobayashi T, Shimabukuro-Demoto S, Tsutsui H, Toyama-Sorimachi N.
Kobayashi T, et al. Among authors: shimabukuro demoto s.
PLoS Biol. 2019 Nov 15;17(11):e3000530. doi: 10.1371/journal.pbio.3000530. eCollection 2019 Nov.
PLoS Biol. 2019.
PMID: 31730616
Free PMC article.
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Human SLC15A4 is crucial for TLR-mediated type I interferon production and mitochondrial integrity.
Kobayashi T, Nguyen-Tien D, Ohshima D, Karyu H, Shimabukuro-Demoto S, Yoshida-Sugitani R, Toyama-Sorimachi N.
Kobayashi T, et al. Among authors: shimabukuro demoto s.
Int Immunol. 2021 Jun 18;33(7):399-406. doi: 10.1093/intimm/dxab006.
Int Immunol. 2021.
PMID: 33560415
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Lysosome biogenesis regulated by the amino-acid transporter SLC15A4 is critical for functional integrity of mast cells.
Kobayashi T, Tsutsui H, Shimabukuro-Demoto S, Yoshida-Sugitani R, Karyu H, Furuyama-Tanaka K, Ohshima D, Kato N, Okamura T, Toyama-Sorimachi N.
Kobayashi T, et al. Among authors: shimabukuro demoto s.
Int Immunol. 2017 Dec 31;29(12):551-566. doi: 10.1093/intimm/dxx063.
Int Immunol. 2017.
PMID: 29155995
Free PMC article.
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The histidine transporter SLC15A4 coordinates mTOR-dependent inflammatory responses and pathogenic antibody production.
Kobayashi T, Shimabukuro-Demoto S, Yoshida-Sugitani R, Furuyama-Tanaka K, Karyu H, Sugiura Y, Shimizu Y, Hosaka T, Goto M, Kato N, Okamura T, Suematsu M, Yokoyama S, Toyama-Sorimachi N.
Kobayashi T, et al. Among authors: shimabukuro demoto s.
Immunity. 2014 Sep 18;41(3):375-388. doi: 10.1016/j.immuni.2014.08.011.
Immunity. 2014.
PMID: 25238095
Free article.
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