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Items: 1 to 20 of 485

1.

Positive effects of low LDL-C and statins on bone mineral density: an integrated epidemiological observation analysis and Mendelian randomization study.

Li GH, Cheung CL, Au PC, Tan KC, Wong IC, Sham PC.

Int J Epidemiol. 2019 Jul 13. pii: dyz145. doi: 10.1093/ije/dyz145. [Epub ahead of print]

PMID:
31302685
2.

WITER: a powerful method for estimation of cancer-driver genes using a weighted iterative regression modelling background mutation counts.

Jiang L, Zheng J, Kwan JSH, Dai S, Li C, Li MJ, Yu B, To KF, Sham PC, Zhu Y, Li M.

Nucleic Acids Res. 2019 Jul 9. pii: gkz566. doi: 10.1093/nar/gkz566. [Epub ahead of print]

PMID:
31287869
3.

Single-cell transcriptomics reveals the landscape of intra-tumoral heterogeneity and stemness-related subpopulations in liver cancer.

Ho DW, Tsui YM, Sze KM, Chan LK, Cheung TT, Lee E, Sham PC, Tsui SK, Lee TK, Ng IO.

Cancer Lett. 2019 Sep 10;459:176-185. doi: 10.1016/j.canlet.2019.06.002. Epub 2019 Jun 10.

PMID:
31195060
4.

LINE1 and Mecp2 methylation of the adult striatum and prefrontal cortex exposed to prenatal immune activation.

Basil P, Li Q, Sham PC, McAlonan GM.

Data Brief. 2019 May 23;25:104003. doi: 10.1016/j.dib.2019.104003. eCollection 2019 Aug.

5.

Commonality in dysregulated expression of gene sets in cortical brains of individuals with autism, schizophrenia, and bipolar disorder.

Guan J, Cai JJ, Ji G, Sham PC.

Transl Psychiatry. 2019 May 24;9(1):152. doi: 10.1038/s41398-019-0488-4.

6.

Publisher Correction: Gene expression imputation across multiple brain regions provides insights into schizophrenia risk.

Huckins LM, Dobbyn A, Ruderfer DM, Hoffman G, Wang W, Pardiñas AF, Rajagopal VM, Als TD, T Nguyen H, Girdhar K, Boocock J, Roussos P, Fromer M, Kramer R, Domenici E, Gamazon ER, Purcell S; CommonMind Consortium; Schizophrenia Working Group of the Psychiatric Genomics Consortium; iPSYCH-GEMS Schizophrenia Working Group, Demontis D, Børglum AD, Walters JTR, O'Donovan MC, Sullivan P, Owen MJ, Devlin B, Sieberts SK, Cox NJ, Im HK, Sklar P, Stahl EA.

Nat Genet. 2019 Jun;51(6):1068. doi: 10.1038/s41588-019-0435-6.

7.

Gene expression imputation across multiple brain regions provides insights into schizophrenia risk.

Huckins LM, Dobbyn A, Ruderfer DM, Hoffman G, Wang W, Pardiñas AF, Rajagopal VM, Als TD, T Nguyen H, Girdhar K, Boocock J, Roussos P, Fromer M, Kramer R, Domenici E, Gamazon ER, Purcell S; CommonMind Consortium; Schizophrenia Working Group of the Psychiatric Genomics Consortium; iPSYCH-GEMS Schizophrenia Working Group, Demontis D, Børglum AD, Walters JTR, O'Donovan MC, Sullivan P, Owen MJ, Devlin B, Sieberts SK, Cox NJ, Im HK, Sklar P, Stahl EA.

Nat Genet. 2019 Apr;51(4):659-674. doi: 10.1038/s41588-019-0364-4. Epub 2019 Mar 25. Erratum in: Nat Genet. 2019 Jun;51(6):1068.

PMID:
30911161
8.

The contribution of cannabis use to variation in the incidence of psychotic disorder across Europe (EU-GEI): a multicentre case-control study.

Di Forti M, Quattrone D, Freeman TP, Tripoli G, Gayer-Anderson C, Quigley H, Rodriguez V, Jongsma HE, Ferraro L, La Cascia C, La Barbera D, Tarricone I, Berardi D, Szöke A, Arango C, Tortelli A, Velthorst E, Bernardo M, Del-Ben CM, Menezes PR, Selten JP, Jones PB, Kirkbride JB, Rutten BP, de Haan L, Sham PC, van Os J, Lewis CM, Lynskey M, Morgan C, Murray RM; EU-GEI WP2 Group.

Lancet Psychiatry. 2019 May;6(5):427-436. doi: 10.1016/S2215-0366(19)30048-3. Epub 2019 Mar 19.

9.

Rational use of mesenchymal stem cells in the treatment of autism spectrum disorders.

Liu Q, Chen MX, Sun L, Wallis CU, Zhou JS, Ao LJ, Li Q, Sham PC.

World J Stem Cells. 2019 Feb 26;11(2):55-72. doi: 10.4252/wjsc.v11.i2.55. Review.

10.

Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia.

Harold D, Connolly S, Riley BP, Kendler KS, McCarthy SE, McCombie WR, Richards A, Owen MJ, O'Donovan MC, Walters J; Wellcome Trust Case Control Consortium 2; Schizophrenia Working Group of the Psychiatric Genomics Consortium, Donohoe G, Gill M, Corvin A, Morris DW.

Am J Med Genet B Neuropsychiatr Genet. 2019 Apr;180(3):223-231. doi: 10.1002/ajmg.b.32716. Epub 2019 Feb 23.

PMID:
30801977
11.

A joint study of whole exome sequencing and structural MRI analysis in major depressive disorder.

Zhang Y, Li M, Wang Q, Hsu JS, Deng W, Ma X, Ni P, Zhao L, Tian Y, Sham PC, Li T.

Psychol Med. 2019 Feb 6:1-12. doi: 10.1017/S0033291719000072. [Epub ahead of print]

PMID:
30722798
12.

High risk Epstein-Barr virus variants characterized by distinct polymorphisms in the EBER locus are strongly associated with nasopharyngeal carcinoma.

Hui KF, Chan TF, Yang W, Shen JJ, Lam KP, Kwok H, Sham PC, Tsao SW, Kwong DL, Lung ML, Chiang AKS.

Int J Cancer. 2019 Jun 15;144(12):3031-3042. doi: 10.1002/ijc.32049. Epub 2019 Jan 7.

PMID:
30536939
13.

Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies.

International League Against Epilepsy Consortium on Complex Epilepsies.

Nat Commun. 2018 Dec 10;9(1):5269. doi: 10.1038/s41467-018-07524-z.

14.

Identifying the genetic causes for prenatally diagnosed structural congenital anomalies (SCAs) by whole-exome sequencing (WES).

Leung GKC, Mak CCY, Fung JLF, Wong WHS, Tsang MHY, Yu MHC, Pei SLC, Yeung KS, Mok GTK, Lee CP, Hui APW, Tang MHY, Chan KYK, Liu APY, Yang W, Sham PC, Kan ASY, Chung BHY.

BMC Med Genomics. 2018 Oct 25;11(1):93. doi: 10.1186/s12920-018-0409-z.

15.

Age-Biomarkers-Clinical Risk Factors for Prediction of Cardiovascular Events in Patients With Coronary Artery Disease.

Wong YK, Cheung CYY, Tang CS, Au KW, Hai JSH, Lee CH, Lau KK, Cheung BMY, Sham PC, Xu A, Lam KSL, Tse HF.

Arterioscler Thromb Vasc Biol. 2018 Oct;38(10):2519-2527. doi: 10.1161/ATVBAHA.118.311726.

PMID:
30354221
16.

Leveraging genome-wide association and clinical data in revealing schizophrenia subgroups.

Yin L, Cheung EF, Chen RY, Wong EH, Sham PC, So HC.

J Psychiatr Res. 2018 Nov;106:106-117. doi: 10.1016/j.jpsychires.2018.09.010. Epub 2018 Sep 22.

PMID:
30312963
17.

Genetic Regulation of Pigment Epithelium-Derived Factor (PEDF): An Exome-Chip Association Analysis in Chinese Subjects With Type 2 Diabetes.

Cheung CYY, Lee CH, Tang CS, Xu A, Au KW, Fong CHY, Ng KKK, Kwok KHM, Chow WS, Woo YC, Yuen MMA, Hai J, Tan KCB, Lam TH, Tse HF, Sham PC, Lam KSL.

Diabetes. 2019 Jan;68(1):198-206. doi: 10.2337/db18-0500. Epub 2018 Oct 10.

18.

Transdiagnostic dimensions of psychopathology at first episode psychosis: findings from the multinational EU-GEI study.

Quattrone D, Di Forti M, Gayer-Anderson C, Ferraro L, Jongsma HE, Tripoli G, La Cascia C, La Barbera D, Tarricone I, Berardi D, Szöke A, Arango C, Lasalvia A, Tortelli A, Llorca PM, de Haan L, Velthorst E, Bobes J, Bernardo M, Sanjuán J, Santos JL, Arrojo M, Del-Ben CM, Menezes PR, Selten JP; EU-GEI WP2 Group, Jones PB, Kirkbride JB, Richards AL, O'Donovan MC, Sham PC, Vassos E, Rutten BP, van Os J, Morgan C, Lewis CM, Murray RM, Reininghaus U.

Psychol Med. 2019 Jun;49(8):1378-1391. doi: 10.1017/S0033291718002131. Epub 2018 Oct 4.

19.

HIV-1 Tat and methamphetamine co-induced oxidative cellular injury is mitigated by N-acetylcysteine amide (NACA) through rectifying mTOR signaling.

Zeng XF, Li Q, Li J, Wong N, Li Z, Huang J, Yang G, Sham PC, Li SB, Lu G.

Toxicol Lett. 2018 Dec 15;299:159-171. doi: 10.1016/j.toxlet.2018.09.009. Epub 2018 Sep 24.

PMID:
30261225
20.

Identification of Genes Associated With Hirschsprung Disease, Based on Whole-Genome Sequence Analysis, and Potential Effects on Enteric Nervous System Development.

Tang CS, Li P, Lai FP, Fu AX, Lau ST, So MT, Lui KN, Li Z, Zhuang X, Yu M, Liu X, Ngo ND, Miao X, Zhang X, Yi B, Tang S, Sun X, Zhang F, Liu H, Liu Q, Zhang R, Wang H, Huang L, Dong X, Tou J, Cheah KS, Yang W, Yuan Z, Yip KY, Sham PC, Tam PK, Garcia-Barcelo MM, Ngan ES.

Gastroenterology. 2018 Dec;155(6):1908-1922.e5. doi: 10.1053/j.gastro.2018.09.012. Epub 2018 Sep 12.

PMID:
30217742

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