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Items: 1 to 20 of 500

1.

A phase I trial of low-dose inhaled carbon monoxide in sepsis-induced ARDS.

Fredenburgh LE, Perrella MA, Barragan-Bradford D, Hess DR, Peters E, Welty-Wolf KE, Kraft BD, Harris RS, Maurer R, Nakahira K, Oromendia C, Davies JD, Higuera A, Schiffer KT, Englert JA, Dieffenbach PB, Berlin DA, Lagambina S, Bouthot M, Sullivan AI, Nuccio PF, Kone MT, Malik MJ, Porras MAP, Finkelsztein E, Winkler T, Hurwitz S, Serhan CN, Piantadosi CA, Baron RM, Thompson BT, Choi AM.

JCI Insight. 2018 Dec 6;3(23). pii: 124039. doi: 10.1172/jci.insight.124039. [Epub ahead of print]

2.

Resolvin D1, but not resolvin E1, transactivates the epidermal growth factor receptor to increase intracellular calcium and glycoconjugate secretion in rat and human conjunctival goblet cells.

Kaye R, Botten N, Lippestad M, Li D, Hodges RR, Utheim TP, Serhan CN, Dartt DA.

Exp Eye Res. 2018 Dec 1. pii: S0014-4835(18)30697-3. doi: 10.1016/j.exer.2018.11.018. [Epub ahead of print]

PMID:
30513286
3.

Resolving Inflammation - Synthesis, Configurational Assignment and Biological Evaluations of RvD1n-3 DPA.

Hansen TV, Tungen JE, Gerstman L, De Matteis R, Colas RA, Vik A, Chiang N, Serhan CN, Kalesse M, Dalli J.

Chemistry. 2018 Dec 4. doi: 10.1002/chem.201806029. [Epub ahead of print]

PMID:
30511787
4.

Resolution of sickle cell disease associated inflammation and tissue damage with 17R-Resolvin D1.

Matte A, Recchiuti A, Federti E, Koehl B, Mintz T, El Nemer W, Tharaux PL, Brousse V, Andolfo I, Lamolinara A, Weinberg O, Siciliano A, Norris PC, Riley IR, Iolascon A, Serhan CN, Brugnara C, De Franceschi L.

Blood. 2018 Nov 7. pii: blood-2018-07-865378. doi: 10.1182/blood-2018-07-865378. [Epub ahead of print]

PMID:
30404812
5.

Cutting Edge: Human Vagus Produces Specialized Proresolving Mediators of Inflammation with Electrical Stimulation Reducing Proinflammatory Eicosanoids.

Serhan CN, de la Rosa X, Jouvene CC.

J Immunol. 2018 Dec 1;201(11):3161-3165. doi: 10.4049/jimmunol.1800806. Epub 2018 Oct 24.

PMID:
30355784
6.

Resolvin D1 treatment on goblet cell mucin and immune responses in the chronic allergic eye disease (AED) model.

Saban DR, Hodges RR, Mathew R, Reyes NJ, Yu C, Kaye R, Swift W, Botten N, Serhan CN, Dartt DA.

Mucosal Immunol. 2018 Oct 2. doi: 10.1038/s41385-018-0089-1. [Epub ahead of print]

PMID:
30279513
7.

Correction for Diaz et al., "Specialized Proresolving Mediators Rescue Infant Mice from Lethal Citrobacter rodentium Infection and Promote Immunity against Reinfection".

Diaz LA, Altman NH, Khan WN, Serhan CN, Adkins B.

Infect Immun. 2018 Sep 21;86(10). pii: e00363-18. doi: 10.1128/IAI.00363-18. Print 2018 Oct. No abstract available.

8.

Synthesis of protectin D1 analogs: novel pro-resolution and radiotracer agents.

Tungen JE, Aursnes M, Ramon S, Colas RA, Serhan CN, Olberg DE, Nuruddin S, Willoch F, Hansen TV.

Org Biomol Chem. 2018 Sep 19;16(36):6818-6823. doi: 10.1039/c8ob01232f.

PMID:
30204204
9.

Specific oxylipins enhance vertebrate hematopoiesis via the receptor GPR132.

Lahvic JL, Ammerman M, Li P, Blair MC, Stillman ER, Fast EM, Robertson AL, Christodoulou C, Perlin JR, Yang S, Chiang N, Norris PC, Daily ML, Redfield SE, Chan IT, Chatrizeh M, Chase ME, Weis O, Zhou Y, Serhan CN, Zon LI.

Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):9252-9257. doi: 10.1073/pnas.1806077115. Epub 2018 Aug 23.

PMID:
30139917
10.

Targeting lipid mediators in cancer biology.

Sulciner ML, Gartung A, Gilligan MM, Serhan CN, Panigrahy D.

Cancer Metastasis Rev. 2018 Sep;37(2-3):557-572. doi: 10.1007/s10555-018-9754-9.

PMID:
30136088
11.

Distinct Analgesic Actions of DHA and DHA-Derived Specialized Pro-Resolving Mediators on Post-operative Pain After Bone Fracture in Mice.

Zhang L, Terrando N, Xu ZZ, Bang S, Jordt SE, Maixner W, Serhan CN, Ji RR.

Front Pharmacol. 2018 May 1;9:412. doi: 10.3389/fphar.2018.00412. eCollection 2018.

12.

Resolvins in inflammation: emergence of the pro-resolving superfamily of mediators.

Serhan CN, Levy BD.

J Clin Invest. 2018 Jul 2;128(7):2657-2669. doi: 10.1172/JCI97943. Epub 2018 May 14. Review.

13.

Identification of proresolving and inflammatory lipid mediators in human psoriasis.

Sorokin AV, Norris PC, English JT, Dey AK, Chaturvedi A, Baumer Y, Silverman J, Playford MP, Serhan CN, Mehta NN.

J Clin Lipidol. 2018 Jul - Aug;12(4):1047-1060. doi: 10.1016/j.jacl.2018.03.091. Epub 2018 Apr 6.

PMID:
29730187
14.

Signaling pathways activated by resolvin E1 to stimulate mucin secretion and increase intracellular Ca2+ in cultured rat conjunctival goblet cells.

Lippestad M, Hodges RR, Utheim TP, Serhan CN, Dartt DA.

Exp Eye Res. 2018 Aug;173:64-72. doi: 10.1016/j.exer.2018.04.015. Epub 2018 Apr 25.

PMID:
29702100
15.

Identification and structure elucidation of the pro-resolving mediators provides novel leads for resolution pharmacology.

Dalli J, Serhan CN.

Br J Pharmacol. 2018 Apr 21. doi: 10.1111/bph.14336. [Epub ahead of print] Review.

PMID:
29679485
16.

Identification and Complete Stereochemical Assignments of the New Resolvin Conjugates in Tissue Regeneration in Human Tissues that Stimulate Proresolving Phagocyte Functions and Tissue Regeneration.

de la Rosa X, Norris PC, Chiang N, Rodriguez AR, Spur BW, Serhan CN.

Am J Pathol. 2018 Apr;188(4):950-966. doi: 10.1016/j.ajpath.2018.01.004.

PMID:
29571326
17.

Pro-resolving mediators promote resolution in a human skin model of UV-killed Escherichia coli-driven acute inflammation.

Motwani MP, Colas RA, George MJ, Flint JD, Dalli J, Richard-Loendt A, De Maeyer RP, Serhan CN, Gilroy DW.

JCI Insight. 2018 Mar 22;3(6). pii: 94463. doi: 10.1172/jci.insight.94463. [Epub ahead of print]

18.

Biosynthesis of D-Series Resolvins in Skin Provides Insights into their Role in Tissue Repair.

Hellmann J, Sansbury BE, Wong B, Li X, Singh M, Nuutila K, Chiang N, Eriksson E, Serhan CN, Spite M.

J Invest Dermatol. 2018 Sep;138(9):2051-2060. doi: 10.1016/j.jid.2018.03.1498. Epub 2018 Mar 17.

PMID:
29559341
19.

Metabololipidomic profiling of functional immunoresolvent clusters and eicosanoids in mammalian tissues.

Norris PC, Serhan CN.

Biochem Biophys Res Commun. 2018 Oct 7;504(3):553-561. doi: 10.1016/j.bbrc.2018.03.037. Epub 2018 Mar 15.

PMID:
29524409
20.

15-epi-Lipoxin A4, Resolvin D2, and Resolvin D3 Induce NF-κB Regulators in Bacterial Pneumonia.

Sham HP, Walker KH, Abdulnour RE, Krishnamoorthy N, Douda DN, Norris PC, Barkas I, Benito-Figueroa S, Colby JK, Serhan CN, Levy BD.

J Immunol. 2018 Apr 15;200(8):2757-2766. doi: 10.4049/jimmunol.1602090. Epub 2018 Mar 9.

PMID:
29523657

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