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Starvation-induced proteasome assemblies in the nucleus link amino acid supply to apoptosis.
Uriarte M, Sen Nkwe N, Tremblay R, Ahmed O, Messmer C, Mashtalir N, Barbour H, Masclef L, Voide M, Viallard C, Daou S, Abdelhadi D, Ronato D, Paydar M, Darracq A, Boulay K, Desjardins-Lecavalier N, Sapieha P, Masson JY, Sergeev M, Kwok BH, Hulea L, Mallette FA, Milot E, Larrivée B, Wurtele H, Affar EB. Uriarte M, et al. Among authors: sen nkwe n. Nat Commun. 2021 Nov 30;12(1):6984. doi: 10.1038/s41467-021-27306-4. Nat Commun. 2021. PMID: 34848715 Free PMC article.
Monoubiquitination of ASXLs controls the deubiquitinase activity of the tumor suppressor BAP1.
Daou S, Barbour H, Ahmed O, Masclef L, Baril C, Sen Nkwe N, Tchelougou D, Uriarte M, Bonneil E, Ceccarelli D, Mashtalir N, Tanji M, Masson JY, Thibault P, Sicheri F, Yang H, Carbone M, Therrien M, Affar EB. Daou S, et al. Among authors: sen nkwe n. Nat Commun. 2018 Oct 22;9(1):4385. doi: 10.1038/s41467-018-06854-2. Nat Commun. 2018. PMID: 30349006 Free PMC article.
A potent nuclear export mechanism imposes USP16 cytoplasmic localization during interphase.
Sen Nkwe N, Daou S, Uriarte M, Gagnon J, Iannantuono NV, Barbour H, Yu H, Masclef L, Fernández E, Zamorano Cuervo N, Mashtalir N, Binan L, Sergeev M, Bélanger F, Drobetsky E, Milot E, Wurtele H, Costantino S, Affar EB. Sen Nkwe N, et al. J Cell Sci. 2020 Feb 24;133(4):jcs239236. doi: 10.1242/jcs.239236. J Cell Sci. 2020. PMID: 32005696