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Relationship of Circulating Growth/Differentiation Factors 8 and 11 and Their Antagonists as Measured Using Liquid Chromatography-Tandem Mass Spectrometry with Age and Skeletal Muscle Strength in Healthy Adults.

Semba RD, Zhang P, Zhu M, Fabbri E, Gonzalez-Freire M, Carlson OD, Moaddel R, Tanaka T, Egan JM, Ferrucci L.

J Gerontol A Biol Sci Med Sci. 2018 Oct 31. doi: 10.1093/gerona/gly255. [Epub ahead of print]


The Association of Fibroblast Growth Factor-23 (FGF-23) with Incident Frailty in HIV-Infected and -Uninfected Individuals.

Wang R, Shlipak MG, Ix JH, Brown TT, Jacobson LP, Palella FJ Jr, Lake JE, Koletar SL, Semba RD, Estrella MM.

J Acquir Immune Defic Syndr. 2018 Oct 1. doi: 10.1097/QAI.0000000000001868. [Epub ahead of print]


Inflammation and micronutrient biomarkers predict clinical HIV treatment failure and incident active TB in HIV-infected adults: a case-control study.

Shivakoti R, Gupte N, Tripathy S, Poongulali S, Kanyama C, Berendes S, Cardoso SW, Santos BR, La Rosa A, Mwelase N, Pillay S, Samaneka W, Riviere C, Sugandhavesa P, Bollinger RC, Balagopal A, Semba RD, Christian P, Campbell TB, Gupta A; NWCS 319 and PEARLS Study Team.

BMC Med. 2018 Sep 24;16(1):161. doi: 10.1186/s12916-018-1150-3.


Plasma proteomic signature of age in healthy humans.

Tanaka T, Biancotto A, Moaddel R, Moore AZ, Gonzalez-Freire M, Aon MA, Candia J, Zhang P, Cheung F, Fantoni G; CHI consortium, Semba RD, Ferrucci L.

Aging Cell. 2018 Oct;17(5):e12799. doi: 10.1111/acel.12799. Epub 2018 Jul 11.


Altered Plasma Amino Acids and Lipids Associated With Abnormal Glucose Metabolism and Insulin Resistance in Older Adults.

Semba RD, Gonzalez-Freire M, Moaddel R, Sun K, Fabbri E, Zhang P, Carlson OD, Khadeer M, Chia CW, Salem N Jr, Ferrucci L.

J Clin Endocrinol Metab. 2018 Sep 1;103(9):3331-3339. doi: 10.1210/jc.2018-00480.


Effect of baseline micronutrient and inflammation status on CD4 recovery post-cART initiation in the multinational PEARLS trial.

Shivakoti R, Ewald ER, Gupte N, Yang WT, Kanyama C, Cardoso SW, Santos B, Supparatpinyo K, Badal-Faesen S, Lama JR, Lalloo U, Zulu F, Pawar JS, Riviere C, Kumarasamy N, Hakim J, Pollard R, Detrick B, Balagopal A, Asmuth DM, Semba RD, Campbell TB, Golub J, Gupta A; NWCS 319 and ACTG PEARLS Study Team.

Clin Nutr. 2018 May 29. pii: S0261-5614(18)30199-7. doi: 10.1016/j.clnu.2018.05.014. [Epub ahead of print]


Targeted Metabolomics Shows Low Plasma Lysophosphatidylcholine 18:2 Predicts Greater Decline of Gait Speed in Older Adults: The Baltimore Longitudinal Study of Aging.

Gonzalez-Freire M, Moaddel R, Sun K, Fabbri E, Zhang P, Khadeer M, Salem N Jr, Ferrucci L, Semba RD.

J Gerontol A Biol Sci Med Sci. 2018 May 17. doi: 10.1093/gerona/gly100. [Epub ahead of print]


Kenneth John Carpenter, Ph.D. (1923-2016).

Semba RD.

J Nutr. 2018 Feb 1;148(2):167-169. doi: 10.1093/jn/nxx014. No abstract available.


The Human Eye Proteome Project: Updates on an Emerging Proteome.

Ahmad MT, Zhang P, Dufresne C, Ferrucci L, Semba RD.

Proteomics. 2018 Mar;18(5-6):e1700394. doi: 10.1002/pmic.201700394. Review.


A proteomic approach to understanding the pathogenesis of idiopathic macular hole formation.

Zhang P, Zhu M, Zhao Y, Qian J, Dufresne C, Turner R, Semba RD, Solomon SD.

Clin Proteomics. 2017 Nov 15;14:37. doi: 10.1186/s12014-017-9172-y. eCollection 2017.


Low serum ω-3 and ω-6 polyunsaturated fatty acids and other metabolites are associated with poor linear growth in young children from rural Malawi.

Semba RD, Trehan I, Li X, Salem N Jr, Moaddel R, Ordiz MI, Maleta KM, Kraemer K, Manary MJ.

Am J Clin Nutr. 2017 Dec;106(6):1490-1499. doi: 10.3945/ajcn.117.164384. Epub 2017 Oct 25.


Plasma klotho and frailty in older adults: Findings from the InCHIANTI Study.

Shardell M, Semba RD, Kalyani RR, Bandinelli S, Prather AA, Chia CW, Ferrucci L.

J Gerontol A Biol Sci Med Sci. 2017 Oct 19. doi: 10.1093/gerona/glx202. [Epub ahead of print]


A targeted proteomic assay for the measurement of plasma proteoforms related to human aging phenotypes.

Semba RD, Zhang P, Zhu M, Fabbri E, Gonzalez-Freire M, Moaddel R, Geng-Spyropoulos M, Ferrucci L.

Proteomics. 2017 Aug;17(15-16). doi: 10.1002/pmic.201600232.


Vitamin A and D Deficiencies Associated With Incident Tuberculosis in HIV-Infected Patients Initiating Antiretroviral Therapy in Multinational Case-Cohort Study.

Tenforde MW, Yadav A, Dowdy DW, Gupte N, Shivakoti R, Yang WT, Mwelase N, Kanyama C, Pillay S, Samaneka W, Santos B, Poongulali S, Tripathy S, Riviere C, Berendes S, Lama JR, Cardoso SW, Sugandhavesa P, Christian P, Semba RD, Campbell TB, Gupta A; NWCS319 and ACTG 5175 study team.

J Acquir Immune Defic Syndr. 2017 Jul 1;75(3):e71-e79. doi: 10.1097/QAI.0000000000001308.


Environmental Enteric Dysfunction is Associated with Carnitine Deficiency and Altered Fatty Acid Oxidation.

Semba RD, Trehan I, Li X, Moaddel R, Ordiz MI, Maleta KM, Kraemer K, Shardell M, Ferrucci L, Manary M.

EBioMedicine. 2017 Mar;17:57-66. doi: 10.1016/j.ebiom.2017.01.026. Epub 2017 Jan 18.


Association between Soluble Klotho and Change in Kidney Function: The Health Aging and Body Composition Study.

Drew DA, Katz R, Kritchevsky S, Ix J, Shlipak M, Gutiérrez OM, Newman A, Hoofnagle A, Fried L, Semba RD, Sarnak M.

J Am Soc Nephrol. 2017 Jun;28(6):1859-1866. doi: 10.1681/ASN.2016080828. Epub 2017 Jan 19.


The Association of Vitamin D Deficiency and Incident Frailty in Older Women: The Role of Cardiometabolic Diseases.

Buta B, Choudhury PP, Xue QL, Chaves P, Bandeen-Roche K, Shardell M, Semba RD, Walston J, Michos ED, Appel LJ, McAdams-DeMarco M, Gross A, Yasar S, Ferrucci L, Fried LP, Kalyani RR.

J Am Geriatr Soc. 2017 Mar;65(3):619-624. doi: 10.1111/jgs.14677. Epub 2016 Dec 23.


The CAPN2/CAPN8 Locus on Chromosome 1q Is Associated with Variation in Serum Alpha-Carotene Concentrations.

D'Adamo CR, Dawson VJ, Ryan KA, Yerges-Armstrong LM, Semba RD, Steinle NI, Mitchell BD, Shuldiner AR, McArdle PF.

J Nutrigenet Nutrigenomics. 2016;9(5-6):254-264. doi: 10.1159/000452890. Epub 2016 Dec 22.


Association of Serum Klotho with Loss of Bone Mineral Density and Fracture Risk in Older Adults.

Chalhoub D, Marques E, Meirelles O, Semba RD, Ferrucci L, Satterfield S, Nevitt M, Cauley JA, Harris T; Health ABC Study.

J Am Geriatr Soc. 2016 Dec;64(12):e304-e308. doi: 10.1111/jgs.14661. Epub 2016 Dec 2.


The Human Skeletal Muscle Proteome Project: a reappraisal of the current literature.

Gonzalez-Freire M, Semba RD, Ubaida-Mohien C, Fabbri E, Scalzo P, Højlund K, Dufresne C, Lyashkov A, Ferrucci L.

J Cachexia Sarcopenia Muscle. 2017 Feb;8(1):5-18. doi: 10.1002/jcsm.12121. Epub 2016 Aug 3. Review.

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