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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 1
1981 2
1990 1
1994 3
1995 1
1996 2
1997 1
1998 5
1999 3
2000 1
2001 4
2002 3
2003 1
2004 2
2005 2
2010 2
2012 1
2016 1
2017 1
2018 2
2021 1
2023 1
2024 0

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40 results

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Page 1
The structure and function of lipoxygenase.
Nelson MJ, Seitz SP. Nelson MJ, et al. Among authors: seitz sp. Curr Opin Struct Biol. 1994 Dec;4(6):878-84. doi: 10.1016/0959-440x(94)90270-4. Curr Opin Struct Biol. 1994. PMID: 7712291 Review.
Discovery and Preclinical Evaluation of BMS-986242, a Potent, Selective Inhibitor of Indoleamine-2,3-dioxygenase 1.
Cherney EC, Zhang L, Nara S, Zhu X, Gullo-Brown J, Maley D, Lin TA, Hunt JT, Huang C, Yang Z, Darienzo C, Discenza L, Ranasinghe A, Grubb M, Ziemba T, Traeger SC, Li X, Johnston K, Kopcho L, Fereshteh M, Foster K, Stefanski K, Fargnoli J, Swanson J, Brown J, Delpy D, Seitz SP, Borzilleri R, Vite G, Balog A. Cherney EC, et al. Among authors: seitz sp. ACS Med Chem Lett. 2021 Jan 28;12(2):288-294. doi: 10.1021/acsmedchemlett.0c00668. eCollection 2021 Feb 11. ACS Med Chem Lett. 2021. PMID: 33603977 Free PMC article.
Synthesis and biological evaluation of biaryl alkyl ethers as inhibitors of IDO1.
Markwalder JA, Balog AJ, Williams DK, Nara SJ, Reddy R, Roy S, Kanyaboina Y, Li X, Johnston K, Fan Y, Lewis H, Marsilio F, Yan C, Critton D, Newitt JA, Traeger SC, Wu DR, Jure-Kunkel MN, Jayaraman L, Lin TA, Sinz MW, Hunt JT, Seitz SP. Markwalder JA, et al. Among authors: seitz sp. Bioorg Med Chem Lett. 2023 May 15;88:129280. doi: 10.1016/j.bmcl.2023.129280. Epub 2023 Apr 11. Bioorg Med Chem Lett. 2023. PMID: 37054759
Quinazolines as cyclin dependent kinase inhibitors.
Sielecki TM, Johnson TL, Liu J, Muckelbauer JK, Grafstrom RH, Cox S, Boylan J, Burton CR, Chen H, Smallwood A, Chang CH, Boisclair M, Benfield PA, Trainor GL, Seitz SP. Sielecki TM, et al. Among authors: seitz sp. Bioorg Med Chem Lett. 2001 May 7;11(9):1157-60. doi: 10.1016/s0960-894x(01)00185-8. Bioorg Med Chem Lett. 2001. PMID: 11354366
Immune-modulating enzyme indoleamine 2,3-dioxygenase is effectively inhibited by targeting its apo-form.
Nelp MT, Kates PA, Hunt JT, Newitt JA, Balog A, Maley D, Zhu X, Abell L, Allentoff A, Borzilleri R, Lewis HA, Lin Z, Seitz SP, Yan C, Groves JT. Nelp MT, et al. Among authors: seitz sp. Proc Natl Acad Sci U S A. 2018 Mar 27;115(13):3249-3254. doi: 10.1073/pnas.1719190115. Epub 2018 Mar 12. Proc Natl Acad Sci U S A. 2018. PMID: 29531094 Free PMC article.
Development of a series of novel o-phenylenediamine-based indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors.
Williams DK, Markwalder JA, Balog AJ, Chen B, Chen L, Donnell J, Haque L, Hart AC, Mandal SK, Nation A, Shan W, Vite GD, Covello K, Hunt JT, Jure-Kunkel MN, Seitz SP. Williams DK, et al. Among authors: seitz sp. Bioorg Med Chem Lett. 2018 Feb 15;28(4):732-736. doi: 10.1016/j.bmcl.2018.01.010. Epub 2018 Jan 11. Bioorg Med Chem Lett. 2018. PMID: 29398543
SAR of PXR transactivation in benzimidazole-based IGF-1R kinase inhibitors.
Zimmermann K, Wittman MD, Saulnier MG, Velaparthi U, Sang X, Frennesson DB, Struzynski C, Seitz SP, He L, Carboni JM, Li A, Greer AF, Gottardis M, Attar RM, Yang Z, Balimane P, Discenza LN, Lee FY, Sinz M, Kim S, Vyas D. Zimmermann K, et al. Among authors: seitz sp. Bioorg Med Chem Lett. 2010 Mar 1;20(5):1744-8. doi: 10.1016/j.bmcl.2010.01.087. Epub 2010 Jan 21. Bioorg Med Chem Lett. 2010. PMID: 20153189
40 results